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Exosome component 1
mammalian protein found in Homo sapiens
exosome complex component CSL4
EXOSC1
3'-5' exoribonuclease CSL4 homolog
homolog of yeast exosomal core protein CSL4
exosomal core protein CSL4
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9Y3B2
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9Y3B2
encoded by
EXOSC1
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9Y3B2
molecular function
exoribonuclease activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Reconstitution, activities, and structure of the eukaryotic RNA exosome
GOA
curator
UniProt
UniProt protein ID
Q9Y3B2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IDA
protein binding
determination method
IPI
12 references
retrieved
8 April 2019
stated in
Protein-protein interactions of hCsl4p with other human exosome subunits
GOA
curator
UniProt
UniProt protein ID
Q9Y3B2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IPI
retrieved
8 April 2019
stated in
DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling
GOA
curator
UniProt
UniProt protein ID
Q9Y3B2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IPI
retrieved
8 April 2019
stated in
The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IPI
retrieved
8 April 2019
stated in
Protein-protein interactions of hCsl4p with other human exosome subunits
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IPI
retrieved
8 April 2019
stated in
Structure of an Rrp6–RNA exosome complex bound to poly(A) RNA
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IPI
retrieved
8 April 2019
stated in
Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IPI
retrieved
8 April 2019
stated in
The association of the human PM/Scl-75 autoantigen with the exosome is dependent on a newly identified N terminus
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IPI
retrieved
8 April 2019
stated in
A protein interaction framework for human mRNA degradation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IPI
retrieved
8 April 2019
stated in
An empirical framework for binary interactome mapping
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IPI
retrieved
8 April 2019
stated in
Pooled-matrix protein interaction screens using Barcode Fusion Genetics
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IPI
RNA binding
determination method
NAS
IEA
3 references
retrieved
8 April 2019
stated in
Protein-protein interactions of hCsl4p with other human exosome subunits
GOA
curator
UniProt
UniProt protein ID
Q9Y3B2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
NAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y3B2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IEA
cell component
cytoplasm
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y3B2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IBA
cytosol
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
TAS
nuclear exosome (RNase complex)
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IBA
nucleolus
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y3B2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IEA
retrieved
8 April 2019
stated in
Protein-protein interactions of hCsl4p with other human exosome subunits
GOA
curator
UniProt
UniProt protein ID
Q9Y3B2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IDA
exosome (RNase complex)
determination method
NAS
IDA
IEA
4 references
retrieved
8 April 2019
stated in
Protein-protein interactions of hCsl4p with other human exosome subunits
GOA
curator
UniProt
UniProt protein ID
Q9Y3B2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
NAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y3B2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IEA
retrieved
8 April 2019
stated in
Dis3-like 1: a novel exoribonuclease associated with the human exosome
GOA
curator
UniProt
UniProt protein ID
Q9Y3B2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IDA
nucleoplasm
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
TAS
nucleus
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y3B2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IEA
biological process
regulation of mRNA stability
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
TAS
exonucleolytic catabolism of deadenylated mRNA
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
TAS
rRNA processing
determination method
IEA
TAS
2 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9Y3B2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IEA
RNA phosphodiester bond hydrolysis, exonucleolytic
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IEA
RNA processing
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y3B2
determination method
IEA
Identifiers
RefSeq protein ID
NP_001305291
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
51013
NP_001305292
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
51013
NP_001305293
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
51013
NP_001305294
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
51013
NP_001305295
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
51013
NP_057130
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
51013
XP_011538149
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
51013
XP_016871793
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
51013
XP_024303801
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
51013
UniProt protein ID
Q9Y3B2
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9Y3B2
Ensembl protein ID
ENSP00000359939
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000359939
ENSP00000359921
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000359921
ENSP00000359922
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000359922
ENSP00000359923
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000359923
ENSP00000473303
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000473303
ENSP00000473660
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000473660
PDB structure ID
2NN6
1 reference
stated in
UniProt
UniProt protein ID
Q9Y3B2
retrieved
9 August 2016
language of work or name
English
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