Wikidata

(Q21118710)

English

Retinoid X receptor alpha

mammalian protein found in Homo sapiens

  • retinoid X nuclear receptor alpha
  • RXRA
  • nuclear receptor subfamily 2 group B member 1
  • retinoic acid receptor RXR-alpha
In more languages

Statements

molecular function
protein binding
determination method
IPI
31 references
retrieved
8 April 2019
stated in
Loss of CAK phosphorylation of RAR{alpha} mediates transcriptional control of retinoid-induced cancer cell differentiation
GOA
curator
UniProt
UniProt protein ID
P19793
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
The basic helix-loop-helix proteins differentiated embryo chondrocyte (DEC) 1 and DEC2 function as corepressors of retinoid X receptors
GOA
curator
UniProt
UniProt protein ID
P19793
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Interaction of hepatitis C virus core protein with retinoid X receptor alpha modulates its transcriptional activity
GOA
curator
UniProt
UniProt protein ID
P19793
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Retinoid-dependent recruitment of a histone H1 displacement activity by retinoic acid receptor
GOA
curator
UniProt
UniProt protein ID
P19793
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Transcription factors and nuclear receptors interact with the SWI/SNF complex through the BAF60c subunit
GOA
curator
UniProt
UniProt protein ID
P19793
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion
GOA
curator
UniProt
UniProt protein ID
P19793
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolism
GOA
curator
UniProt
UniProt protein ID
P19793
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Activation of LXR increases acyl-CoA synthetase activity through direct regulation of ACSL3 in human placental trophoblast cells
GOA
curator
UniProt
UniProt protein ID
P19793
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Interleukin-6 Induces DEC1, Promotes DEC1 Interaction with RXRα and Suppresses the Expression of PXR, CAR and Their Target Genes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis for negative cooperativity within agonist-bound TR:RXR heterodimers
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Structure of the full human RXR/VDR nuclear receptor heterodimer complex with its DR3 target DNA
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Helix 11 dynamics is critical for constitutive androstane receptor activity.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Structural and Functional Analysis of the Human Nuclear Xenobiotic Receptor PXR in Complex with RXRα
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Structural and functional characterization of a novel type of ligand-independent RXR-USP receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Molecular determinants of the interactions between SRC-1 and LXR/RXR heterodimers
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Interaction of hepatitis C virus core protein with retinoid X receptor alpha modulates its transcriptional activity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Structure of the retinoid X receptor α-liver X receptor β (RXRα-LXRβ) heterodimer on DNA
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
NSAID sulindac and its analog bind RXRalpha and inhibit RXRalpha-dependent AKT signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Enhancer activation requires trans-recruitment of a mega transcription factor complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
A new family of nuclear receptor coregulators that integrate nuclear receptor signaling through CREB-binding protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Phosphorylation by PKA potentiates retinoic acid receptor alpha activity by means of increasing interaction with and phosphorylation by cyclin H/cdk7.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
Selective use of multiple vitamin D response elements underlies the 1 alpha,25-dihydroxyvitamin D3-mediated negative regulation of the human CYP27B1 gene
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
retrieved
8 April 2019
stated in
The core component of the mammalian SWI/SNF complex SMARCD3/BAF60c is a coactivator for the nuclear retinoic acid receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19793
determination method
IPI
cell component
biological process

Identifiers

PDB structure ID
 
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