(Q24317341)

English

The nuclear receptor Rev-erbalpha is a liver X receptor (LXR) target gene driving a negative feedback loop on select LXR-induced pathways in human macrophages

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scholarly article

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The nuclear receptor Rev-erbalpha is a liver X receptor (LXR) target gene driving a negative feedback loop on select LXR-induced pathways in human macrophages (English)

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Nuclear receptor subfamily 1 group D member 1

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GOA release 2020-03-11

Retinoid X receptor alpha

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GOA release 2020-03-11

Nuclear receptor subfamily 1 group H member 3

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GOA release 2020-03-11

8

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Jean-Charles Fruchart

6

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Christian Duhem

object named as

Christian Duhem

5

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object named as

Benoit Pourcet

3

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Coralie Fontaine

object named as

Coralie Fontaine

1

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4

object named as

Hélène Duez

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Giulia Chinetti-Gbaguidi

7

object named as

Giulia Chinetti-Gbaguidi

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author name string

Elena Rigamonti

2

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language of work or name

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publication date

August 2008

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Molecular Endocrinology

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22

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8

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1797-811

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Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

26 May 2017

Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

26 May 2017

Pathogen recognition and innate immunity

1 reference

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26 May 2017

Differential control of Bmal1 circadian transcription by REV-ERB and ROR nuclear receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

26 May 2017

Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages

1 reference

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26 May 2017

Obesity and metabolic syndrome in circadian Clock mutant mice

1 reference

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26 May 2017

ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins

1 reference

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26 May 2017

Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

1 reference

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26 May 2017

A transcription factor response element for gene expression during circadian night

1 reference

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26 May 2017

The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

26 May 2017

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

26 May 2017

The nuclear receptors peroxisome proliferator-activated receptor alpha and Rev-erbalpha mediate the species-specific regulation of apolipoprotein A-I expression by fibrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

26 May 2017

A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

26 May 2017

Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

26 May 2017

The orphan nuclear receptor Rev-erbalpha: a transcriptional link between circadian rhythmicity and cardiometabolic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

27 September 2017

Toll-like receptor 4 siRNA attenuates LPS-induced secretion of inflammatory cytokines and chemokines by macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

27 September 2017

Liver X receptors as integrators of metabolic and inflammatory signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

27 September 2017

The innate immune response under the control of the LXR pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

27 September 2017

Genomic structure, promoter analysis and expression of the porcine (Sus scrofa) TLR4 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

27 September 2017

The role of the orphan nuclear receptor Rev-Erb alpha in adipocyte differentiation and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

27 September 2017

Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

27 September 2017

The orphan receptor Rev-erbalpha gene is a target of the circadian clock pacemaker

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

27 September 2017

LXR-dependent gene expression is important for macrophage survival and the innate immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

27 September 2017

Rev-erbalpha upregulates NF-kappaB-responsive genes in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

27 September 2017

The orphan nuclear receptor Rev-Erbalpha is a peroxisome proliferator-activated receptor (PPAR) gamma target gene and promotes PPARgamma-induced adipocyte differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

27 September 2017

Identification of Rev-erbalpha as a physiological repressor of apoC-III gene transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

27 September 2017

Transcriptional regulation of human Rev-erbalpha gene expression by the orphan nuclear receptor retinoic acid-related orphan receptor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

27 September 2017

Orphan nuclear hormone receptor Rev-erbalpha regulates the human apolipoprotein CIII promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

27 September 2017

Phosphorylation of histone H3 is functionally linked to retinoic acid receptor beta promoter activation

1 reference

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27 September 2017

The human ABCG4 gene is regulated by oxysterols and retinoids in monocyte-derived macrophages

1 reference

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27 September 2017

Modulation of the far-upstream enhancer of the rat alpha-fetoprotein gene by members of the ROR alpha, Rev-erb alpha, and Rev-erb beta groups of monomeric orphan nuclear receptors

1 reference

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27 September 2017

Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor

1 reference

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27 September 2017

Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction

1 reference

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27 September 2017

Transcriptional regulation of apolipoprotein A-I gene expression by the nuclear receptor RORalpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

27 September 2017

Induction of Rev-ErbA alpha, an orphan receptor encoded on the opposite strand of the alpha-thyroid hormone receptor gene, during adipocyte differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

27 September 2017

The monomer-binding orphan receptor Rev-Erb represses transcription as a dimer on a novel direct repeat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

27 September 2017

A novel member of the thyroid/steroid hormone receptor family is encoded by the opposite strand of the rat c-erbA alpha transcriptional unit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

27 September 2017

Adverse effects of modest sleep restriction on sleepiness, performance, and inflammatory cytokines

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30 May 2018

Transcriptional cross-talk, the second mode of steroid hormone receptor action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

30 May 2018

Liver X Receptor Activation Potentiates the Lipopolysaccharide Response in Human Macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

29 November 2018

Dioscorin isolated from Dioscorea alata activates TLR4-signaling pathways and induces cytokine expression in macrophages

1 reference

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29 November 2018

Atypical patterns of circadian clock gene expression in human peripheral blood mononuclear cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

29 November 2018

A Nuclear Receptor Atlas: macrophage activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

29 November 2018

Aberrant expression of myosin isoforms in skeletal muscles from mice lacking the rev-erbAalpha orphan receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

29 November 2018

Orphan nuclear receptors, molecular clockwork, and the entrainment of peripheral oscillators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

29 November 2018

Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419447

29 November 2018

A carboxyl-terminal extension of the zinc finger domain contributes to the specificity and polarity of peroxisome proliferator-activated receptor DNA binding

1 reference

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LXR activation reduces proinflammatory cytokine expression in human CD4-positive lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18511497

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circadian and glucocorticoid regulation of Rev-erbalpha expression in liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/18511497

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibrates increase human REV-ERBalpha expression in liver via a novel peroxisome proliferator-activated receptor response element

1 reference

https://pubmed.ncbi.nlm.nih.gov/18511497

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orphan nuclear hormone receptor RevErbalpha modulates expression from the promoter of the hydratase-dehydrogenase gene by inhibiting peroxisome proliferator-activated receptor alpha-dependent transactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18511497

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma : a molecular basis for priming and synergism with bacterial lipopolysaccharide

1 reference

https://pubmed.ncbi.nlm.nih.gov/18511497

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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