(Q21122712)

WD40/YVTN repeat-like-containing domain superfamily

1 reference

WD40-repeat-containing domain superfamily

1 reference

Vacuolar protein sorting-associated protein 41

1 reference

Zinc finger, RING-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

Clathrin, heavy chain/VPS, 7-fold repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

1 reference

8 April 2019

protein self-association

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

protein binding

5 references

8 April 2019

Vps33b pathogenic mutations preferentially affect VIPAS39/SPE-39-positive endosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

8 April 2019

Structural basis of Vps33A recruitment to the human HOPS complex by Vps16

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

8 April 2019

RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

8 April 2019

SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

identical protein binding

1 reference

8 April 2019

Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

GTPase binding

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49754&geneProductId=UniProtKB:P49754

1 reference

26 September 2017

cell component

HOPS complex

cytosol

1 reference

26 September 2017

hVPS41 is expressed in multiple isoforms and can associate with vesicles through a RING-H2 finger motif

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49754&geneProductId=UniProtKB:P49754

endosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

1 reference

8 April 2019

Golgi apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

1 reference

8 April 2019

late endosome membrane

1 reference

8 April 2019

The HOPS proteins hVps41 and hVps39 are required for homotypic and heterotypic late endosome fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

microtubule cytoskeleton

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

clathrin complex

1 reference

8 April 2019

Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

lysosomal membrane

CORVET complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49754&geneProductId=UniProtKB:P49754

1 reference

26 September 2017

lysosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

1 reference

8 April 2019

cytoplasmic vesicle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

1 reference

8 April 2019

late endosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

Golgi-associated vesicle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

1 reference

8 April 2019

HOPS complex

Structural basis of Vps33A recruitment to the human HOPS complex by Vps16

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

8 April 2019

SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

biological process

endosomal vesicle fusion

1 reference

8 April 2019

The HOPS proteins hVps41 and hVps39 are required for homotypic and heterotypic late endosome fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

endosome to lysosome transport

1 reference

8 April 2019

Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

late endosome to lysosome transport

1 reference

8 April 2019

The HOPS proteins hVps41 and hVps39 are required for homotypic and heterotypic late endosome fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

1 reference

8 April 2019

Golgi vesicle transport

1 reference

26 September 2017

hVPS41 is expressed in multiple isoforms and can associate with vesicles through a RING-H2 finger motif

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49754&geneProductId=UniProtKB:P49754

vacuole fusion, non-autophagic

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

protein transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

1 reference

8 April 2019

regulated exocytosis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

protein targeting to vacuole

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49754&geneProductId=UniProtKB:P49754

1 reference

26 September 2017

intracellular protein transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

1 reference

8 April 2019

regulation of SNARE complex assembly

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

vesicle-mediated transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

1 reference

8 April 2019

intracellular transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49754

1 reference

8 April 2019

transport

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49754&geneProductId=UniProtKB:P49754

1 reference

26 September 2017

Clathrin, heavy chain/VPS, 7-fold repeat

has part(s)

1 reference

Zinc finger, RING-type

1 reference