Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q21125179)
Watch
English
Sestrin 3
mammalian protein found in Homo sapiens
SESN3
sestrin-3
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P58005
part of
AhpD-like
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P58005
sestrin
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P58005
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P58005
encoded by
SESN3
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P58005
molecular function
oxidoreductase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P58005
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IEA
protein binding
determination method
IPI
2 references
retrieved
8 April 2019
stated in
Sestrin2 is a leucine sensor for the mTORC1 pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IPI
retrieved
8 April 2019
stated in
The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IPI
oxidoreductase activity, acting on peroxide as acceptor
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IBA
leucine binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IBA
cell component
nucleus
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IEA
cytoplasm
determination method
IEA
IDA
2 references
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P58005
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P58005&geneProductId=UniProtKB:P58005
determination method
IEA
retrieved
24 April 2018
stated in
The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1
GOA
curator
UniProt
UniProt protein ID
P58005
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P58005&geneProductId=UniProtKB:P58005
determination method
IDA
GATOR2 complex
determination method
IDA
2 references
retrieved
24 April 2018
stated in
Sestrin2 is a leucine sensor for the mTORC1 pathway
GOA
curator
UniProt
UniProt protein ID
P58005
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P58005&geneProductId=UniProtKB:P58005
determination method
IDA
retrieved
24 April 2018
stated in
The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1
GOA
curator
UniProt
UniProt protein ID
P58005
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P58005&geneProductId=UniProtKB:P58005
determination method
IDA
TORC2 complex
determination method
IEA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P58005&geneProductId=UniProtKB:P58005
determination method
IEA
cytoplasm
determination method
IBA
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P58005
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IEA
retrieved
8 April 2019
stated in
The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1
GOA
curator
UniProt
UniProt protein ID
P58005
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IBA
TORC2 complex
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IBA
GATOR2 complex
determination method
IBA
IDA
3 references
retrieved
8 April 2019
stated in
Sestrin2 is a leucine sensor for the mTORC1 pathway
GOA
curator
UniProt
UniProt protein ID
P58005
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IDA
retrieved
8 April 2019
stated in
The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1
GOA
curator
UniProt
UniProt protein ID
P58005
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IBA
biological process
regulation of response to reactive oxygen species
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IEA
negative regulation of TORC1 signaling
determination method
IEA
IMP
2 references
retrieved
24 April 2018
stated in
The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1
GOA
curator
UniProt
UniProt protein ID
P58005
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P58005&geneProductId=UniProtKB:P58005
determination method
IMP
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P58005&geneProductId=UniProtKB:P58005
determination method
IEA
response to insulin
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IEA
glucose homeostasis
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IEA
regulation of protein kinase B signaling
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IEA
TORC2 signaling
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IEA
regulation of insulin receptor signaling pathway
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IEA
cellular response to amino acid starvation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1
GOA
curator
UniProt
UniProt protein ID
P58005
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IMP
cellular response to glucose starvation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1
GOA
curator
UniProt
UniProt protein ID
P58005
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IMP
cellular response to amino acid stimulus
determination method
IEA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P58005&geneProductId=UniProtKB:P58005
determination method
IEA
positive regulation of macroautophagy
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IBA
cellular response to amino acid stimulus
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IBA
cellular response to leucine
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IBA
negative regulation of TORC1 signaling
determination method
IBA
IEA
IMP
3 references
retrieved
8 April 2019
stated in
The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1
GOA
curator
UniProt
UniProt protein ID
P58005
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IBA
cellular response to leucine starvation
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58005
determination method
IBA
Identifiers
RefSeq protein ID
NP_001258523
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
143686
NP_653266
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
143686
XP_011540916
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
143686
XP_024304123
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
143686
UniProt protein ID
P58005
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P58005
Ensembl protein ID
ENSP00000278499
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000278499
ENSP00000407008
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000407008
ENSP00000441927
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000441927
ENSP00000439580
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000439580
ENSP00000489281
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000489281
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
