Wikidata

(Q21127053)

English

Ring finger protein 168

mammalian protein found in Homo sapiens

  • RNF168
  • ring finger protein 168, E3 ubiquitin protein ligase
  • E3 ubiquitin-protein ligase RNF168
  • RING-type E3 ubiquitin transferase RNF168
  • RING finger protein 168
In more languages
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No label defined

No description defined

Statements

molecular function
ubiquitin-protein transferase activity
determination method or standard
IDA
IEA
IMP
8 references
retrieved
8 April 2019
stated in
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark
GOA
curator
UniProt
UniProt protein ID
Q8IYW5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
determination method or standard
IMP
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8IYW5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
determination method or standard
IEA
retrieved
8 April 2019
stated in
RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX
GOA
curator
UniProt
UniProt protein ID
Q8IYW5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
determination method or standard
IDA
retrieved
8 April 2019
stated in
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
GOA
curator
UniProt
UniProt protein ID
Q8IYW5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
determination method or standard
IDA
retrieved
8 April 2019
stated in
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
GOA
curator
UniProt
UniProt protein ID
Q8IYW5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
determination method or standard
IDA
retrieved
8 April 2019
stated in
RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites
GOA
curator
UniProt
UniProt protein ID
Q8IYW5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
determination method or standard
IDA
retrieved
8 April 2019
stated in
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
GOA
curator
UniProt
UniProt protein ID
Q8IYW5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
determination method or standard
IDA
cell component
biological process
cellular response to DNA damage stimulus
determination method or standard
IDA
IEA
6 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8IYW5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
determination method or standard
IEA
retrieved
8 April 2019
stated in
RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX
GOA
curator
UniProt
UniProt protein ID
Q8IYW5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
determination method or standard
IDA
retrieved
8 April 2019
stated in
DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger
GOA
curator
UniProt
UniProt protein ID
Q8IYW5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
determination method or standard
IDA
retrieved
8 April 2019
stated in
RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites
GOA
curator
UniProt
UniProt protein ID
Q8IYW5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
determination method or standard
IDA
retrieved
8 April 2019
stated in
ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks
GOA
curator
UniProt
UniProt protein ID
Q8IYW5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
determination method or standard
IDA
retrieved
8 April 2019
stated in
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
GOA
curator
UniProt
UniProt protein ID
Q8IYW5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYW5
determination method or standard
IDA

Identifiers

 
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