(Q24298746)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0036351

histone H2A-K15 ubiquitination

2 references

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0036352

GOA release 2020-03-11

Ring finger protein 168

1 reference

GOA release 2020-03-11

Ring finger protein 8

1 reference

GOA release 2020-03-11

protein ubiquitination

1 reference

6

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Titia Sixma

8

object named as

Titia K Sixma

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author name string

Francesca Mattiroli

1

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Joseph H A Vissers

2

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Willem J van Dijk

3

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Pauline Ikpa

4

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Elisabetta Citterio

5

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Jurgen A Marteijn

Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin

7

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language of work or name

English

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publication date

14 September 2012

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published in

Cell

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volume

150

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page(s)

1182-95

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issue

6

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cites work

1 reference

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7 January 2021

Amino-terminal sequence identity of ubiquitin and the nonhistone component of nuclear protein A24

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7 January 2021

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

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7 January 2021

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

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7 January 2021

Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies

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7 January 2021

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

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https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage

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7 January 2021

ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks

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https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes

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7 January 2021

Regulatory ubiquitylation in response to DNA double-strand breaks

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7 January 2021

Structural aspects of multi-domain RING/Ubox E3 ligases in DNA repair.

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7 January 2021

The ubiquitous role of ubiquitin in the DNA damage response

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7 January 2021

Beyond ATM: the protein kinase landscape of the DNA damage response

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7 January 2021

The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks

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7 January 2021

RNF20-RNF40: A ubiquitin-driven link between gene expression and the DNA damage response.

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7 January 2021

Symmetry and asymmetry of the RING-RING dimer of Rad18

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7 January 2021

Structural characterization of proteins and complexes using small-angle X-ray solution scattering.

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7 January 2021

Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases

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https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7

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https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing

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https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination

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7 January 2021

Regulation of homologous recombination by RNF20-dependent H2B ubiquitination.

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7 January 2021

Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks

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https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Determination of domain structure of proteins from X-ray solution scattering

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https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Solvent mediated interactions in the structure of the nucleosome core particle at 1.9 a resolution

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Crystal structure of the nucleosome core particle at 2.8 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Role of histone H2A ubiquitination in Polycomb silencing

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Direct activation of protein kinases by unanchored polyubiquitin chains

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

RAD18 transmits DNA damage signalling to elicit homologous recombination repair

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Structure of a BRCA1-BARD1 heterodimeric RING-RING complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

The E3 ligase RNF8 regulates KU80 removal and NHEJ repair

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

An anticlastogenic function for the Polycomb Group gene Bmi1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Isopeptide linkage between nonhistone and histone 2A polypeptides of chromosomal conjugate-protein A24

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Monoubiquitination of H2AX protein regulates DNA damage response signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Critical role of monoubiquitination of histone H2AX protein in histone H2AX phosphorylation and DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Structure of a Bmi-1-Ring1B polycomb group ubiquitin ligase complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Automatic rebuilding and optimization of crystallographic structures in the Protein Data Bank

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Asymmetric nature of two subunits of RAD18, a RING-type ubiquitin ligase E3, in the human RAD6A-RAD18 ternary complex.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Refinement of severely incomplete structures with maximum likelihood in BUSTER-TNT

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Coot: model-building tools for molecular graphics

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Developments in the CCP4 molecular-graphics project

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Scaling and assessment of data quality

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Solving structures of protein complexes by molecular replacement with Phaser

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

A multivariate likelihood SIRAS function for phasing and model refinement

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Experimental phasing with SHELXC/D/E: combining chain tracing with density modification

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

1 reference

7 January 2021

The CCP4 suite: programs for protein crystallography

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Genomic instability in mice lacking histone H2AX

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

53BP1, a mediator of the DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

UMI, a novel RNF168 ubiquitin binding domain involved in the DNA damage signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

Expression and purification of recombinant histones and nucleosome reconstitution

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

p97/VCP- and Lys48-linked polyubiquitination form a new signaling pathway in DNA damage response.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021

PCNA is ubiquitinated by RNF8

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.08.005

7 January 2021