(Q24298486)

L3MBTL1, histone methyl-lysine binding protein

GOA release 2020-03-11

1 reference

methylated histone binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Leena Ackermann

3

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Nico P. Dantuma

object named as

Nico P Dantuma

6

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Thorsten Hoppe

object named as

Thorsten Hoppe

5

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author name string

Klara Acs

1

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Martijn S Luijsterburg

2

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Florian A Salomons

Nature Structural & Molecular Biology

4

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language of work or name

English

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publication date

December 2011

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published in

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volume

18

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issue

12

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page(s)

1345-50

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cites work

The DNA-damage response in human biology and disease

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Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

21 January 2018

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MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

21 January 2018

1 reference

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

21 January 2018

1 reference

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

21 January 2018

1 reference

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

21 January 2018

1 reference

The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage

21 January 2018

1 reference

DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A

21 January 2018

1 reference

The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks

21 January 2018

1 reference

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

21 January 2018

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RAD18 transmits DNA damage signalling to elicit homologous recombination repair

21 January 2018

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Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage

21 January 2018

1 reference

Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

21 January 2018

1 reference

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

21 January 2018

1 reference

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

21 January 2018

1 reference

How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers

21 January 2018

1 reference

MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites

21 January 2018

1 reference

The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair

21 January 2018

1 reference

Cdc48 (p97): a "molecular gearbox" in the ubiquitin pathway?

21 January 2018

1 reference

Sculpting the proteome with AAA(+) proteases and disassembly machines.

21 January 2018

1 reference

Cdc48: a power machine in protein degradation

21 January 2018

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CDC-48/p97 coordinates CDT-1 degradation with GINS chromatin dissociation to ensure faithful DNA replication

21 January 2018

1 reference

A genome-wide screen identifies p97 as an essential regulator of DNA damage-dependent CDT1 destruction.

21 January 2018

1 reference

Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage

21 January 2018

1 reference

A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways

21 January 2018

1 reference

The ubiquitin-selective chaperone CDC-48/p97 links myosin assembly to human myopathy

21 January 2018

1 reference

Cell cycle progression requires the CDC-48UFD-1/NPL-4 complex for efficient DNA replication

21 January 2018

1 reference

Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation

21 January 2018

1 reference

BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair

21 January 2018

1 reference

BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair

21 January 2018

1 reference

The DNA damage response pathways: at the crossroad of protein modifications

21 January 2018

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Activation of the cellular DNA damage response in the absence of DNA lesions

21 January 2018

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A dynamic ubiquitin equilibrium couples proteasomal activity to chromatin remodeling

21 January 2018

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RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling

21 January 2018

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Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

21 January 2018

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VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD

21 January 2018

1 reference

Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains

21 January 2018

1 reference

Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger

21 January 2018

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L3MBTL1 recognition of mono- and dimethylated histones

21 January 2018

1 reference

Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor

21 January 2018

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L3MBTL1, a histone-methylation-dependent chromatin lock

21 January 2018

1 reference

Chromatin and the DNA damage response: the cancer connection.

21 January 2018

1 reference

Monoubiquitination of H2AX protein regulates DNA damage response signaling

21 January 2018

1 reference

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

21 January 2018

1 reference

The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene Repression

21 January 2018

1 reference

Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans

21 January 2018

1 reference

Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin

21 January 2018

1 reference

The genetics of Caenorhabditis elegans

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22120668