Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q21130487)
Watch
English
Exosome component 8
mammalian protein found in Homo sapiens
exosome complex component RRP43
CBP-interacting protein 3
OIP-2
EXOSC8
p9
ribosomal RNA-processing protein 43
Opa-interacting protein 2
exosome complex exonuclease RRP43
Opa interacting protein 2
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q96B26
part of
Exosome complex component Rrp43
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q96B26
Exoribonuclease, PH domain 2 superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q96B26
Ribosomal protein S5 domain 2-type fold
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q96B26
PNPase/RNase PH domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q96B26
Exoribonuclease, phosphorolytic domain 2, protein family
1 reference
based on heuristic
inferred from protein domain or family
Exoribonuclease, phosphorolytic domain 1, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q96B26
encoded by
EXOSC8
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q96B26
molecular function
exoribonuclease activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Reconstitution, activities, and structure of the eukaryotic RNA exosome
GOA
curator
UniProt
UniProt protein ID
Q96B26
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IDA
protein binding
determination method
IPI
9 references
retrieved
8 April 2019
stated in
Dis3-like 1: a novel exoribonuclease associated with the human exosome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IPI
retrieved
8 April 2019
stated in
The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IPI
retrieved
8 April 2019
stated in
Structure of an Rrp6–RNA exosome complex bound to poly(A) RNA
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IPI
retrieved
8 April 2019
stated in
Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IPI
retrieved
8 April 2019
stated in
A protein interaction framework for human mRNA degradation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IPI
retrieved
8 April 2019
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IPI
retrieved
8 April 2019
stated in
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IPI
RNA binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96B26
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IEA
identical protein binding
determination method
IPI
2 references
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IPI
retrieved
8 April 2019
stated in
A protein interaction framework for human mRNA degradation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IPI
mRNA 3'-UTR AU-rich region binding
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Sequence-specific RNA binding mediated by the RNase PH domain of components of the exosome
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IDA
cell component
cytoplasm
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96B26
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IEA
retrieved
8 April 2019
stated in
Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways
GOA
curator
UniProt
UniProt protein ID
Q96B26
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IDA
cytosol
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
TAS
exosome (RNase complex)
determination method
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96B26
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IEA
retrieved
8 April 2019
stated in
Dis3-like 1: a novel exoribonuclease associated with the human exosome
GOA
curator
UniProt
UniProt protein ID
Q96B26
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IDA
nucleolus
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96B26
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IEA
nucleus
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96B26
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IEA
retrieved
8 April 2019
stated in
Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways
GOA
curator
UniProt
UniProt protein ID
Q96B26
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IDA
nucleoplasm
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
TAS
nuclear exosome (RNase complex)
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IBA
cytoplasmic exosome (RNase complex)
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IBA
biological process
regulation of mRNA stability
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
TAS
RNA processing
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IEA
RNA catabolic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IEA
rRNA processing
determination method
IEA
TAS
2 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96B26
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IEA
exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IBA
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IBA
U1 snRNA 3'-end processing
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IBA
U4 snRNA 3'-end processing
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IBA
U5 snRNA 3'-end processing
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IBA
exonucleolytic catabolism of deadenylated mRNA
determination method
IBA
TAS
2 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
TAS
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IBA
nuclear mRNA surveillance
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IBA
nuclear polyadenylation-dependent rRNA catabolic process
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IBA
nuclear polyadenylation-dependent tRNA catabolic process
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IBA
nuclear polyadenylation-dependent mRNA catabolic process
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IBA
biological process
determination method
ND
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96B26
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
ND
rRNA catabolic process
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96B26
determination method
IBA
physically interacts with
Viroporin 3a
determination method
Affinity Capture-MS
1 reference
reference URL
https://thebiogrid.org/news/227
retrieved
19 April 2020
stated in
BioGRID
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing
has part(s)
Exoribonuclease, phosphorolytic domain 2
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q96B26
Exoribonuclease, phosphorolytic domain 1
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q96B26
Identifiers
RefSeq protein ID
NP_852480
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
11340
XP_006719826
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
11340
UniProt protein ID
Q96B26
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q96B26
Ensembl protein ID
ENSP00000374354
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000374354
ENSP00000239893
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000239893
ENSP00000419203
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000419203
PDB structure ID
2NN6
1 reference
stated in
UniProt
UniProt protein ID
Q96B26
retrieved
9 August 2016
language of work or name
English
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
