(Q21172182)

http://www.ebi.ac.uk/interpro/protein/P20618

Nucleophile aminohydrolases, N-terminal

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20618

Proteasome beta-type subunit, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

16 March 2017

1 reference

16 March 2017

endopeptidase activity

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20618&geneProductId=UniProtKB:P20618

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

4 references

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

8 April 2019

Protein-protein interactions among human 20S proteasome subunits and proteassemblin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

8 April 2019

The proteasome maturation protein POMP facilitates major steps of 20S proteasome formation at the endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

8 April 2019

Immunoproteasomes preserve protein homeostasis upon interferon-induced oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20618&geneProductId=UniProtKB:P20618

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

3 references

8 April 2019

Structure and functions of the 20S and 26S proteasomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

8 April 2019

Mass spectrometric characterization of the affinity-purified human 26S proteasome complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

IDA

extracellular exosome

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20618&geneProductId=UniProtKB:P20618

26 September 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20618&geneProductId=UniProtKB:P20618

26 September 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20618&geneProductId=UniProtKB:P20618

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20618&geneProductId=UniProtKB:P20618

26 September 2017

Proteomic characterization of the human sperm nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20618&geneProductId=UniProtKB:P20618

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20618&geneProductId=UniProtKB:P20618

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

IDA

proteasome core complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

secretory granule lumen

1 reference

8 April 2019

ficolin-1-rich granule lumen

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

proteasome core complex, beta-subunit complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

8 April 2019

Proteomic characterization of the human sperm nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

HDA

proteasome core complex

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

regulation of cellular amino acid metabolic process

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

regulation of mRNA stability

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

positive regulation of canonical Wnt signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

protein polyubiquitination

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

stimulatory C-type lectin receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

tumor necrosis factor-mediated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

Fc-epsilon receptor signaling pathway

IEA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

NIK/NF-kappaB signaling

1 reference

8 April 2019

anaphase-promoting complex-dependent catabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

proteolysis involved in cellular protein catabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

T cell receptor signaling pathway

IEA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

negative regulation of canonical Wnt signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

proteasome-mediated ubiquitin-dependent protein catabolic process

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20618&geneProductId=UniProtKB:P20618

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

Wnt signaling pathway, planar cell polarity pathway

IEA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

negative regulation of G2/M transition of mitotic cell cycle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

protein deubiquitination

1 reference

8 April 2019

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

neutrophil degranulation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

transmembrane transport

1 reference

8 April 2019

regulation of transcription from RNA polymerase II promoter in response to hypoxia

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

post-translational protein modification

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

regulation of hematopoietic stem cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

proteasomal protein catabolic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

proteasomal ubiquitin-independent protein catabolic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

proteasome-mediated ubiquitin-dependent protein catabolic process

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20618&geneProductId=UniProtKB:P20618

interleukin-1-mediated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

regulation of mitotic cell cycle phase transition

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20618

physically interacts with

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL451887

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2141296

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2103884

has part(s)

Proteasome beta-type subunit, conserved site

1 reference

stated in

InterPro Release 71.0