(Q21173277)

English

Interferon gamma

mammalian protein found in Homo sapiens

interferon gamma
IFNG
immune interferon
IFN-gamma

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

1 December 2016

UniProt protein ID

interferon gamma

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01579

four-helical cytokine-like, core

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01579

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

3 references

9 May 2019

Structure and mechanism of IFN- antagonism by an orthopoxvirus IFN- -binding protein

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

9 May 2019

Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

9 May 2019

The structure and activity of a monomeric interferon-gamma:alpha-chain receptor signaling complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

extracellular region

determination method

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

9 May 2019

Missense mutations in the MEFV gene are associated with fibromyalgia syndrome and correlate with elevated IL-1beta plasma levels

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

external side of plasma membrane

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

neuron projection

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

biological process

apoptotic process

determination method

1 reference

9 May 2019

Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of MHC class II biosynthetic process

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

negative regulation of smooth muscle cell proliferation

determination method

1 reference

9 May 2019

Differential effects of insulin-like growth factor-1 and atheroma-associated cytokines on cell proliferation and apoptosis in plaque smooth muscle cells of symptomatic and asymptomatic patients with carotid stenosis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

cellular response to interleukin-18

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

antigen processing and presentation

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity

determination method

1 reference

9 May 2019

HIV-1 p17 and IFN-gamma both induce fructose 1,6-bisphosphatase

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

regulation of transcription, DNA-templated

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

determination method

1 reference

9 May 2019

IFN-gamma-producing human T cells directly induce osteoclastogenesis from human monocytes via the expression of RANKL

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of interleukin-12 production

determination method

3 references

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

17 October 2017

Regulation of bioactive IL-12 production in lipopolysaccharide-stimulated human monocytes is determined by the expression of the p35 subunit

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

17 October 2017

Regulation of interleukin-12 expression in human monocytes: selective priming by interferon-gamma of lipopolysaccharide-inducible p35 and p40 genes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

positive regulation of smooth muscle cell apoptotic process

determination method

1 reference

9 May 2019

Differential effects of insulin-like growth factor-1 and atheroma-associated cytokines on cell proliferation and apoptosis in plaque smooth muscle cells of symptomatic and asymptomatic patients with carotid stenosis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

regulation of insulin secretion

determination method

1 reference

9 May 2019

Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

extrinsic apoptotic signaling pathway

determination method

1 reference

9 May 2019

Differential effects of insulin-like growth factor-1 and atheroma-associated cytokines on cell proliferation and apoptosis in plaque smooth muscle cells of symptomatic and asymptomatic patients with carotid stenosis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

regulation of the force of heart contraction

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

regulation of neuronal action potential

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

positive regulation of synaptic transmission, cholinergic

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

response to virus

determination method

1 reference

9 May 2019

The heat shock protein 90-CDC37 chaperone complex is required for signaling by types I and II interferons

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of membrane protein ectodomain proteolysis

determination method

1 reference

9 May 2019

The role of CXCL16 and its processing metalloproteinases ADAM10 and ADAM17 in the proliferation and migration of human mesangial cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of epithelial cell migration

determination method

1 reference

9 May 2019

Lung epithelial barrier function and wound healing are decreased by IL-4 and IL-13 and enhanced by IFN-gamma

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of osteoclast differentiation

determination method

1 reference

9 May 2019

IFN-gamma-producing human T cells directly induce osteoclastogenesis from human monocytes via the expression of RANKL

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of killing of cells of other organism

determination method

1 reference

9 May 2019

The killing of Leishmania major by human macrophages is mediated by nitric oxide induced after ligation of the Fc epsilon RII/CD23 surface antigen

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of calcidiol 1-monooxygenase activity

determination method

1 reference

9 May 2019

HIV-1 p17 and IFN-gamma both induce fructose 1,6-bisphosphatase

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of peptidyl-serine phosphorylation of STAT protein

determination method

3 references

17 October 2017

Molecular mechanisms underlying the inhibition of IFN-γ-induced, STAT1-mediated gene transcription in human macrophages by simvastatin and agonists of PPARs and LXRs

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

17 October 2017

The heat shock protein 90-CDC37 chaperone complex is required for signaling by types I and II interferons

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

positive regulation of vitamin D biosynthetic process

determination method

1 reference

9 May 2019

HIV-1 p17 and IFN-gamma both induce fructose 1,6-bisphosphatase

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

neutrophil chemotaxis

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

negative regulation of gene expression

determination method

1 reference

8 April 2019

Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of fructose 1,6-bisphosphate metabolic process

determination method

1 reference

9 May 2019

HIV-1 p17 and IFN-gamma both induce fructose 1,6-bisphosphatase

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of transcription, DNA-templated

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

endoplasmic reticulum unfolded protein response

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

cell surface receptor signaling pathway

determination method

1 reference

9 May 2019

Selective diapedesis of Th1 cells induced by endothelial cell RANTES

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of gene expression

determination method

4 references

17 October 2017

Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

17 October 2017

Intestinal epithelial cells secrete exosome-like vesicles

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

17 October 2017

A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

17 October 2017

Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

regulation of interferon-gamma-mediated signaling pathway

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

defense response to bacterium

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

defense response to virus

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of neuron differentiation

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

positive regulation of T cell proliferation

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

regulation of hepatocyte proliferation

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

immune response

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

regulation of immune response

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

positive regulation of tumor necrosis factor production

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

CD8-positive, alpha-beta T cell differentiation involved in immune response

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

neutrophil apoptotic process

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

sensory perception of mechanical stimulus

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

regulation of growth

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of isotype switching to IgG isotypes

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

positive regulation of exosomal secretion

determination method

1 reference

17 October 2017

Intestinal epithelial cells secrete exosome-like vesicles

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response

determination method

1 reference

9 May 2019

A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

negative regulation of interleukin-17 production

determination method

1 reference

9 May 2019

Negative regulation of IL-17 production by OX40/OX40L interaction

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

cellular response to lipopolysaccharide

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

T cell receptor signaling pathway

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

negative regulation of myelination

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

inflammatory cell apoptotic process

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

positive regulation of interleukin-23 production

determination method

1 reference

9 May 2019

Salmonella induced IL-23 and IL-1beta allow for IL-12 production by monocytes and Mphi1 through induction of IFN-gamma in CD56 NK/NK-like T cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of transcription by RNA polymerase II

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

negative regulation of cell population proliferation

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

defense response to protozoan

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

positive regulation of cell adhesion

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

negative regulation of glomerular mesangial cell proliferation

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

negative regulation of fibroblast proliferation

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

regulation of glial cell proliferation

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

positive regulation of apoptotic process

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

positive regulation of protein phosphorylation

determination method

1 reference

9 May 2019

Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

regulation of protein ADP-ribosylation

determination method

1 reference

9 May 2019

Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of protein-containing complex assembly

determination method

1 reference

9 May 2019

Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of tyrosine phosphorylation of STAT protein

determination method

3 references

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

17 October 2017

The heat shock protein 90-CDC37 chaperone complex is required for signaling by types I and II interferons

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

17 October 2017

Cytokine-stimulated GTP cyclohydrolase I expression in endothelial cells requires coordinated activation of nuclear factor-kappaB and Stat1/Stat3

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

regulation of defense response to virus by host

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

interferon-gamma-mediated signaling pathway

determination method

4 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

17 October 2017

Deacetylation of p53 induces autophagy by suppressing Bmf expression

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

17 October 2017

Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

positive regulation of protein serine/threonine kinase activity

determination method

1 reference

9 May 2019

Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of core promoter binding

determination method

1 reference

9 May 2019

Deacetylation of p53 induces autophagy by suppressing Bmf expression

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

interleukin-12-mediated signaling pathway

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

regulation of regulatory T cell differentiation

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of protein localization to plasma membrane

determination method

1 reference

17 October 2017

Intestinal epithelial cells secrete exosome-like vesicles

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579

determination method

regulation of signaling receptor activity

determination method

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

negative regulation of transcription by RNA polymerase II

determination method

1 reference

9 May 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

adaptive immune response

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

humoral immune response

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of cell population proliferation

determination method

1 reference

9 May 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of gene expression

determination method

4 references

8 April 2019

A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

8 April 2019

Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

8 April 2019

Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

8 April 2019

Intestinal epithelial cells secrete exosome-like vesicles

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

negative regulation of epithelial cell differentiation

determination method

1 reference

9 May 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of interleukin-12 production

determination method

positive regulation of peptidyl-serine phosphorylation of STAT protein

determination method

positive regulation of tyrosine phosphorylation of STAT protein

determination method

positive regulation of nitric oxide biosynthetic process

determination method

1 reference

9 May 2019

Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

negative regulation of transcription, DNA-templated

determination method

1 reference

9 May 2019

Deacetylation of p53 induces autophagy by suppressing Bmf expression

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

interferon-gamma-mediated signaling pathway

determination method

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

9 May 2019

Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

9 May 2019

Deacetylation of p53 induces autophagy by suppressing Bmf expression

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of protein deacetylation

determination method

1 reference

9 May 2019

Deacetylation of p53 induces autophagy by suppressing Bmf expression

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of protein localization to plasma membrane

determination method

1 reference

9 May 2019

Intestinal epithelial cells secrete exosome-like vesicles

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of exosomal secretion

determination method

1 reference

9 May 2019

Intestinal epithelial cells secrete exosome-like vesicles

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of protein import into nucleus

determination method

1 reference

9 May 2019

Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

microglial cell activation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of NMDA glutamate receptor activity

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

microglial cell activation

determination method

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

9 May 2019

Interferon-{gamma} differentially affects Alzheimer's disease pathologies and induces neurogenesis in triple transgenic-AD mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

9 May 2019

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

receptor signaling pathway via JAK-STAT

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of gene expression

determination method

7 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

9 May 2019

Insulin-like growth factor 2 receptor is an IFNgamma-inducible microglial protein that facilitates intracellular HIV replication: implications for HIV-induced neurocognitive disorders

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

9 May 2019

Interferon-{gamma} differentially affects Alzheimer's disease pathologies and induces neurogenesis in triple transgenic-AD mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

9 May 2019

A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

9 May 2019

Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

9 May 2019

Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

9 May 2019

Intestinal epithelial cells secrete exosome-like vesicles

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of MHC class II biosynthetic process

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of glycolytic process

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of phagocytosis

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of neurogenesis

determination method

1 reference

9 May 2019

Interferon-{gamma} differentially affects Alzheimer's disease pathologies and induces neurogenesis in triple transgenic-AD mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of nitrogen compound metabolic process

determination method

1 reference

9 May 2019

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of nitric-oxide synthase biosynthetic process

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

neuroinflammatory response

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

negative regulation of amyloid-beta clearance

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of neuron death

determination method

1 reference

9 May 2019

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of cellular respiration

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

negative regulation of tau-protein kinase activity

determination method

1 reference

9 May 2019

Interferon-{gamma} differentially affects Alzheimer's disease pathologies and induces neurogenesis in triple transgenic-AD mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

positive regulation of iron ion import across plasma membrane

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000229135

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000229135

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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