(Q21173281)

http://www.ebi.ac.uk/interpro/protein/Q15185

CS domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

unfolded protein binding

1 reference

8 April 2019

Disassembly of transcriptional regulatory complexes by molecular chaperones

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

1 reference

8 April 2019

Differential regulation of telomerase activity by six telomerase subunits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

7 references

8 April 2019

The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

Hsp90 cochaperones p23 and FKBP4 physically interact with hAgo2 and activate RNA interference-mediated silencing in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

Toward an understanding of the protein interaction network of the human liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

N-terminal domain of human Hsp90 triggers binding to the cochaperone p23.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

prostaglandin-E synthase activity

IPI

3 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

17 October 2017

Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

An unstructured C-terminal region of the Hsp90 co-chaperone p23 is important for its chaperone function

Hsp90 protein binding

3 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

17 October 2017

Crystal structure and activity of human p23, a heat shock protein 90 co-chaperone

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

17 October 2017

A truncated form of p23 down-regulates telomerase activity via disruption of Hsp90 function

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

prostaglandin-E synthase activity

IPI

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

1 January 2018

Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

Crystal structure and activity of human p23, a heat shock protein 90 co-chaperone

Hsp90 protein binding

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

An unstructured C-terminal region of the Hsp90 co-chaperone p23 is important for its chaperone function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

A truncated form of p23 down-regulates telomerase activity via disruption of Hsp90 function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

prostaglandin-E synthase activity

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

1 reference

8 April 2019

Differential regulation of telomerase activity by six telomerase subunits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

telomerase holoenzyme complex

IC

1 reference

8 April 2019

Differential regulation of telomerase activity by six telomerase subunits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

extracellular exosome

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

1 reference

17 October 2017

Proteomic characterization of the human sperm nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

2 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

1 reference

8 April 2019

Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

prostaglandin metabolic process

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

IEA

cyclooxygenase pathway

1 reference

8 April 2019

fatty acid metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

fatty acid biosynthetic process

IEA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

regulation of cellular response to heat

IEA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

prostaglandin biosynthetic process

1 reference

8 April 2019

Differential regulation of telomerase activity by six telomerase subunits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

1 reference

8 April 2019

Characterization of a novel 23-kilodalton protein of unactive progesterone receptor complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

xenobiotic metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

telomere maintenance via telomerase

3 references

17 October 2017

A truncated form of p23 down-regulates telomerase activity via disruption of Hsp90 function

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

17 October 2017

Functional requirement of p23 and Hsp90 in telomerase complexes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

17 October 2017

A truncated form of p23 down-regulates telomerase activity via disruption of Hsp90 function

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

positive regulation of phosphorylation

1 reference

8 April 2019

A truncated form of p23 down-regulates telomerase activity via disruption of Hsp90 function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

positive regulation of telomerase activity

3 references

8 April 2019

A truncated form of p23 down-regulates telomerase activity via disruption of Hsp90 function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

Functional requirement of p23 and Hsp90 in telomerase complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

A truncated form of p23 down-regulates telomerase activity via disruption of Hsp90 function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

telomerase holoenzyme complex assembly

1 reference

17 October 2017

Functional requirement of p23 and Hsp90 in telomerase complexes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

chaperone-mediated protein complex assembly

1 reference

17 October 2017

Crystal structure and activity of human p23, a heat shock protein 90 co-chaperone

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15185&geneProductId=UniProtKB:Q15185

prostaglandin biosynthetic process

IMP

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

telomere maintenance via telomerase

4 references

8 April 2019

A truncated form of p23 down-regulates telomerase activity via disruption of Hsp90 function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

Functional requirement of p23 and Hsp90 in telomerase complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

A truncated form of p23 down-regulates telomerase activity via disruption of Hsp90 function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

chaperone cofactor-dependent protein refolding

1 reference

8 April 2019

Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15185

1 reference

InterPro Release 71.0