(Q21173823)

phospholipase A2

1 reference

Phospholipase A2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Phospholipase A2, histidine active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Phospholipase A2, aspartic acid active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15496&geneProductId=UniProtKB:O15496

1 reference

27 March 2018

phospholipase A2 activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15496&geneProductId=UniProtKB:O15496

4 references

27 March 2018

27 March 2018

Cloning, chromosomal mapping, and expression of a novel human secretory phospholipase A2

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15496&geneProductId=UniProtKB:O15496

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15496&geneProductId=UniProtKB:O15496

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15496&geneProductId=UniProtKB:O15496

27 March 2018

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

1 reference

8 April 2019

hydrolase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

1 reference

8 April 2019

phospholipase A2 activity

Cloning, chromosomal mapping, and expression of a novel human secretory phospholipase A2

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

phospholipid binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

calcium-dependent phospholipase A2 activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

cell component

extracellular region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

3 references

8 April 2019

8 April 2019

Cloning, chromosomal mapping, and expression of a novel human secretory phospholipase A2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

8 April 2019

extracellular space

1 reference

8 April 2019

Innate immunity proteins and a new truncated form of SPLUNC1 in nasopharyngeal aspirates from infants with respiratory syncytial virus infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

extracellular space

phosphatidic acid biosynthetic process

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

1 reference

8 April 2019

positive regulation of protein metabolic process

1 reference

8 April 2019

Macrophage secretory phospholipase A2 group X enhances anti-inflammatory responses, promotes lipid accumulation, and contributes to aberrant lung pathology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

phosphatidylserine acyl-chain remodeling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

1 reference

8 April 2019

phosphatidylethanolamine acyl-chain remodeling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

1 reference

8 April 2019

lysophospholipid transport

1 reference

8 April 2019

Secretory phospholipases A2 induce neurite outgrowth in PC12 cells through lysophosphatidylcholine generation and activation of G2A receptor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

lipid metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

1 reference

8 April 2019

positive regulation of lipid storage

1 reference

8 April 2019

Macrophage secretory phospholipase A2 group X enhances anti-inflammatory responses, promotes lipid accumulation, and contributes to aberrant lung pathology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

phosphatidylinositol acyl-chain remodeling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

1 reference

8 April 2019

axon guidance

1 reference

8 April 2019

Secretory phospholipases A2 induce neurite outgrowth in PC12 cells through lysophosphatidylcholine generation and activation of G2A receptor

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

positive regulation of prostaglandin secretion

1 reference

8 April 2019

Macrophage secretory phospholipase A2 group X enhances anti-inflammatory responses, promotes lipid accumulation, and contributes to aberrant lung pathology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

positive regulation of macrophage derived foam cell differentiation

IC

1 reference

8 April 2019

Macrophage secretory phospholipase A2 group X enhances anti-inflammatory responses, promotes lipid accumulation, and contributes to aberrant lung pathology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

phosphatidylglycerol acyl-chain remodeling

IC

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

1 reference

8 April 2019

arachidonic acid metabolic process

NAS

1 reference

8 April 2019

Macrophage secretory phospholipase A2 group X enhances anti-inflammatory responses, promotes lipid accumulation, and contributes to aberrant lung pathology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

phosphatidylcholine acyl-chain remodeling

NAS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

1 reference

8 April 2019

regulation of macrophage activation

1 reference

8 April 2019

Macrophage secretory phospholipase A2 group X enhances anti-inflammatory responses, promotes lipid accumulation, and contributes to aberrant lung pathology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

phospholipid metabolic process

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15496&geneProductId=UniProtKB:O15496

1 reference

27 March 2018

arachidonic acid secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

1 reference

8 April 2019

cellular response to leukemia inhibitory factor

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

axon guidance

positive regulation of lipid storage

positive regulation of protein metabolic process

positive regulation of prostaglandin secretion

cholesterol homeostasis

Group X Secretory Phospholipase A 2 Negatively Regulates ABCA1 and ABCG1 Expression and Cholesterol Efflux in Macrophages

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

regulation of macrophage activation

negative regulation of DNA-binding transcription factor activity

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

8 April 2019

Group X Secretory Phospholipase A 2 Negatively Regulates ABCA1 and ABCG1 Expression and Cholesterol Efflux in Macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

lysophospholipid transport

positive regulation of arachidonic acid secretion

Group X Secretory Phospholipase A 2 Negatively Regulates ABCA1 and ABCG1 Expression and Cholesterol Efflux in Macrophages

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

negative regulation of cholesterol efflux

Group X Secretory Phospholipase A 2 Negatively Regulates ABCA1 and ABCG1 Expression and Cholesterol Efflux in Macrophages

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15496

Phospholipase A2, aspartic acid active site

has part(s)

1 reference

Phospholipase A2, histidine active site

1 reference

Phospholipase A2 domain

1 reference

D08.811.277.352.100.680.750.937.750.887

Identifiers

MeSH descriptor ID

D054509

subject named as

Group X Phospholipases A2

0 references

MeSH tree code

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

4 August 2016

language of work or name

1 reference

4 August 2016

language of work or name

1 reference

4 August 2016

language of work or name

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023