(Q21202226)

http://www.ebi.ac.uk/interpro/protein/Q9NZ71

P-loop containing nucleoside triphosphate hydrolase

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9NZ71

ATP-dependent helicase, C-terminal domain, protein family

1 reference

DEAD2, protein family

1 reference

Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type, protein family

1 reference

Helicase-like, DEXD box c2 type, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

3 references

8 April 2019

IOP1 protein is an external component of the human cytosolic iron-sulfur cluster assembly (CIA) machinery and functions in the MMS19 protein-dependent CIA pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal-Hreidarsson syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

3 references

16 July 2018

RTEL1 maintains genomic stability by suppressing homologous recombination

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZ71&geneProductId=UniProtKB:Q9NZ71

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZ71&geneProductId=UniProtKB:Q9NZ71

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZ71&geneProductId=UniProtKB:Q9NZ71

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

2 references

iron-sulfur cluster binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

4 iron, 4 sulfur cluster binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZ71&geneProductId=UniProtKB:Q9NZ71

DNA helicase activity

5 references

16 July 2018

16 July 2018

RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZ71&geneProductId=UniProtKB:Q9NZ71

16 July 2018

RTEL1 maintains genomic stability by suppressing homologous recombination

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZ71&geneProductId=UniProtKB:Q9NZ71

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZ71&geneProductId=UniProtKB:Q9NZ71

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZ71&geneProductId=UniProtKB:Q9NZ71

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

DNA helicase activity

6 references

8 April 2019

8 April 2019

RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

RTEL1 maintains genomic stability by suppressing homologous recombination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

4 references

8 April 2019

RTEL1 maintains genomic stability by suppressing homologous recombination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

DNA polymerase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

IOP1 protein is an external component of the human cytosolic iron-sulfur cluster assembly (CIA) machinery and functions in the MMS19 protein-dependent CIA pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

1 reference

16 July 2018

RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZ71&geneProductId=UniProtKB:Q9NZ71

positive regulation of telomeric loop disassembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

nucleobase-containing compound metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

positive regulation of telomere capping

1 reference

8 April 2019

Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal-Hreidarsson syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

negative regulation of telomere maintenance in response to DNA damage

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

positive regulation of telomere maintenance

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

mitotic telomere maintenance via semi-conservative replication

1 reference

8 April 2019

RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

cellular response to DNA damage stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

telomere maintenance in response to DNA damage

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

replication fork processing

1 reference

8 April 2019

RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

positive regulation of telomere maintenance via telomere lengthening

1 reference

8 April 2019

Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal-Hreidarsson syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

Constitutional mutations in RTEL1 cause severe dyskeratosis congenita

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

2 references

regulation of double-strand break repair via homologous recombination

1 reference

27 March 2018

RTEL1 maintains genomic stability by suppressing homologous recombination

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZ71&geneProductId=UniProtKB:Q9NZ71

negative regulation of DNA recombination

IMP

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZ71&geneProductId=UniProtKB:Q9NZ71

negative regulation of t-circle formation

3 references

16 July 2018

RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZ71&geneProductId=UniProtKB:Q9NZ71

16 July 2018

RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZ71&geneProductId=UniProtKB:Q9NZ71

16 July 2018

TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZ71&geneProductId=UniProtKB:Q9NZ71

regulation of double-strand break repair via homologous recombination

IMP

3 references

8 April 2019

RTEL1 maintains genomic stability by suppressing homologous recombination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

telomeric loop disassembly

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

negative regulation of t-circle formation

4 references

8 April 2019

RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ71