(Q21260401)

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Frequent expression loss of Inter-alpha-trypsin inhibitor heavy chain (ITIH) genes in multiple human solid tumors: a systematic expression analysis

scientific article

Frequent expression loss of Inter-alpha-trypsin inhibitor heavy chain (ITIH) genes in multiple human solid tumors: A systematic expression analysis

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Frequent expression loss of Inter-alpha-trypsin inhibitor heavy chain (ITIH) genes in multiple human solid tumors: a systematic expression analysis (English)

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11

object named as

Edgar Dahl

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Edgar

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Dahl

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Dimensions Publication ID

18 August 2022

Ruth Knüchel-Clarke

10

object named as

Ruth Knuechel

author given names

Ruth

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Knuechel

1 reference

Dimensions Publication ID

18 August 2022

5

author given names

Arndt

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Hartmann

object named as

Arndt Hartmann

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18 August 2022

Glen Kristiansen

7

author given names

Glen

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Kristiansen

object named as

Glen Kristiansen

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18 August 2022

3

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Nuran

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Bektas

object named as

Nuran Bektas

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18 August 2022

6

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Uwe

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Heindrichs

object named as

Uwe Heindrichs

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18 August 2022

author name string

Alexander Hamm

1

author given names

Alexander

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Hamm

1 reference

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18 August 2022

Juergen Veeck

2

author given names

Juergen

author last names

Veeck

1 reference

Dimensions Publication ID

18 August 2022

Peter J Wild

4

author given names

Peter J

author last names

Wild

1 reference

Dimensions Publication ID

18 August 2022

Tamra Werbowetski-Ogilvie

8

author given names

Tamra

author last names

Werbowetski-Ogilvie

1 reference

Dimensions Publication ID

18 August 2022

Rolando Del Maestro

9

author given names

Rolando

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Del Maestro

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18 August 2022

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publication date

2008

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8

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1

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25

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The protease inhibitor bikunin, a novel anti-metastatic agent

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19 March 2017

ITIH4 serum concentration increases during acute-phase processes in human patients and is up-regulated by interleukin-6 in hepatocarcinoma HepG2 cells

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19 March 2017

Human inter-alpha-trypsin inhibitor heavy chain H3 gene. Genomic organization, promoter analysis, and gene linkage

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19 March 2017

Human plasma inter-alpha-trypsin inhibitor is encoded by four genes on three chromosomes

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19 March 2017

Expression levels of the putative zinc transporter LIV-1 are associated with a better outcome of breast cancer patients

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19 March 2017

Systematic identification and molecular characterization of genes differentially expressed in breast and ovarian cancer

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19 March 2017

Inhibition of tumor growth and metastatic spreading by overexpression of inter-alpha-trypsin inhibitor family chains

1 reference

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19 March 2017

Identification of sonic hedgehog-responsive genes using cDNA microarray

1 reference

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19 March 2017

Gene expression of the two heavy chains and one light chain forming the inter-alpha-trypsin-inhibitor in human tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

19 March 2017

A serum-derived hyaluronan-associated protein (SHAP) is the heavy chain of the inter alpha-trypsin inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

19 March 2017

Two out of the three kinds of subunits of inter-alpha-trypsin inhibitor are structurally related

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

19 March 2017

Molecular profiling of laser-microdissected matched tumor and normal breast tissue identifies karyopherin alpha2 as a potential novel prognostic marker in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

Expression analysis of mammaglobin A (SCGB2A2) and lipophilin B (SCGB1D2) in more than 300 human tumors and matching normal tissues reveals their co-expression in gynecologic malignancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

Extracellular matrix integrity: a possible mechanism for differential clinical effects among selective estrogen receptor modulators and estrogens?

1 reference

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12 September 2017

Systematic characterisation of GABRP expression in sporadic breast cancer and normal breast tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

Inter-alpha-inhibitor proteins are endogenous furin inhibitors and provide protection against experimental anthrax intoxication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

The TSG-6 and I alpha I interaction promotes a transesterification cleaving the protein-glycosaminoglycan-protein (PGP) cross-link.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

Inter-alpha-trypsin inhibitor, a covalent protein-glycosaminoglycan-protein complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

A physiological function of serum proteoglycan bikunin: the chondroitin sulfate moiety plays a central role.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

Mononuclear leukocytes bind to specific hyaluronan structures on colon mucosal smooth muscle cells treated with polyinosinic acid:polycytidylic acid: inter-alpha-trypsin inhibitor is crucial to structure and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

Role of plasminogen activator-plasmin system in tumor angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

TSG-6: a multifunctional protein associated with inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

The new human tissue kallikrein gene family: structure, function, and association to disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

Generation of full-length cDNA libraries enriched for differentially expressed genes for functional genomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

Bikunin--not just a plasma proteinase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

Inter-alpha-inhibitor binding to hyaluronan in the cumulus extracellular matrix is required for optimal ovulation and development of mouse oocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

Real-time quantitative RT-PCR after laser-assisted cell picking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

A bifunctional hybrid molecule of the amino-terminal fragment of urokinase and domain II of bikunin efficiently inhibits tumor cell invasion and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

TNF/IL-1-inducible protein TSG-6 potentiates plasmin inhibition by inter-alpha-inhibitor and exerts a strong anti-inflammatory effect in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

Consistent chromosome 3p deletion and loss of heterozygosity in renal cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

Hyaluronan and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

66The inter-α-trypsin inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

12 September 2017

The extracellular matrix protein ITIH5 is a novel prognostic marker in invasive node-negative breast cancer and its aberrant expression is caused by promoter hypermethylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

27 September 2017

Estrogen-regulated gene networks in human breast cancer cells: involvement of E2F1 in the regulation of cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

27 September 2017

Characterization of complexes formed between TSG-6 and inter-alpha-inhibitor that act as intermediates in the covalent transfer of heavy chains onto hyaluronan.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

27 September 2017

Genetic down-regulation of phosphoinositide 3-kinase by bikunin correlates with suppression of invasion and metastasis in human ovarian cancer HRA cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

27 September 2017

Gene expression profiling in RAS oncogene-transformed cell lines and in solid tumors using subtractive suppression hybridization and cDNA arrays.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

27 September 2017

The inter-alpha-inhibitor family: from structure to regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

27 September 2017

Post-translational processing of the inter-α-trypsin inhibitor in the human hepatoma HepG2 cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

27 September 2017

Specificity of the tumor necrosis factor-induced protein 6-mediated heavy chain transfer from inter-alpha-trypsin inhibitor to hyaluronan: implications for the assembly of the cumulus extracellular matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

30 May 2018

Estrogen receptor mediated inhibition of cancer cell invasion and motility: an overview

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

30 May 2018

Inter-alpha-trypsin inhibitor proteoglycan family--a group of proteins binding and stabilizing the extracellular matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

30 May 2018

An estrogen-responsive element derived from the 5' flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268946

30 May 2018

ITIH5, a novel member of the inter-alpha-trypsin inhibitor heavy chain family is downregulated in breast cancer

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-8-25

21 January 2018

Role of tumour necrosis factor stimulated gene 6 (TSG-6) in the coupling of inter-alpha-trypsin inhibitor to hyaluronan in human follicular fluid

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-8-25

21 January 2018

TSG-6 and calcium ions are essential for the coupling of inter-alpha-trypsin inhibitor to hyaluronan in human synovial fluid

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-8-25

21 January 2018

Administration of human inter-alpha-inhibitors maintains hemodynamic stability and improves survival during sepsis

1 reference

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21 January 2018

Correlation between mortality and the levels of inter-alpha inhibitors in the plasma of patients with severe sepsis.

1 reference

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21 January 2018

Isolation of a natural inhibitor of human malignant glial cell invasion: inter alpha-trypsin inhibitor heavy chain 2.

1 reference

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21 January 2018

The New Human Tissue Kallikrein Gene Family: Structure, Function, and Association to Disease1

1 reference

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29 November 2018

Plasminogen activator in synovial fluid from patients with rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18226209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activator dependent pathways in the dissemination of human tumor cells in the chick embryo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18226209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mapping of deletion sites in the short arm of chromosome 3 in human lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18226209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three discrete regions of deletion at 3p in head and neck cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/18226209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effect of a conjugate between human urokinase and urinary trypsin inhibitor on tumor cell invasion in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/18226209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of metastasis of lewis lung carcinoma by urinary trypsin inhibitor in experimental and spontaneous metastasis models

1 reference

https://pubmed.ncbi.nlm.nih.gov/18226209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effect of bikunin on calcium oxalate crystallization in vitro and urinary bikunin decrease in renal stone formers

1 reference

https://pubmed.ncbi.nlm.nih.gov/18226209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Longitudinal studies of inter-alpha inhibitor proteins in severely septic patients: a potential clinical marker and mediator of severe sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18226209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular proteolysis and cancer: meeting summary and future directions

1 reference

https://pubmed.ncbi.nlm.nih.gov/18226209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of urinary trypsin inhibitor on pancreatic enzymes and experimental acute pancreatitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18226209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Recommendation for uniform definition of an immunoreactive score (IRS) for immunohistochemical estrogen receptor detection (ER-ICA) in breast cancer tissue]

1 reference

https://pubmed.ncbi.nlm.nih.gov/18226209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1471-2407-8-25

1 reference

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OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

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1 reference

Consolidated OpenCitations Corpus – April 2017

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1 reference

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