(Q21261427)

English

A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E epsilon4 allele

scientific article

A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E ε4 allele

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scholarly article

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/PMC/2396156

A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E epsilon4 allele (English)

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/PMC/2396156

Alzheimer's disease

1 reference

based on heuristic

inferred from title

Robert D. Schnabel

2

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/PMC/2408608

John L. Williams

14

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/PMC/2408608

author name string

Ryan J Haasl

1

author given names

Ryan J

author last names

Haasl

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/PMC/2396156

Sivan Vadakkadath Meethal

3

author given names

Sivan Vadakkadath

author last names

Meethal

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/PMC/2396156

Carey E Gleason

4

author given names

Carey E

author last names

Gleason

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/PMC/2396156

Sterling C Johnson

5

author given names

Sterling C

author last names

Johnson

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/PMC/2396156

Sanjay Asthana

6

author given names

Sanjay

author last names

Asthana

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/PMC/2396156

Richard L Bowen

7

author given names

Richard L

author last names

Bowen

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/PMC/2396156

Craig S Atwood

8

author given names

Craig S

author last names

Atwood

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/PMC/2396156

M Reza Ahmadi

author given names

M Reza

author last names

Ahmadi

2

1 reference

17 August 2022

language of work or name

0 references

publication date

25 April 2008

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/PMC/2396156

BMC Medical Genetics

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/PMC/2396156

9

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/PMC/2396156

1

0 references

37

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/PMC/2396156

https://scigraph.springernature.com/pub.10.1186/1471-2350-9-37

0 references

Intronic microRNA (miRNA)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

6 April 2017

An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene interactions on risk of myocardial infarction: the importance of model validation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

19 March 2017

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

19 March 2017

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

19 March 2017

Structure of the human luteinizing hormone-choriogonadotropin receptor gene: unusual promoter and 5' non-coding regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

19 March 2017

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

19 March 2017

Luteinizing hormone receptor mediates neuronal pregnenolone production via up-regulation of steroidogenic acute regulatory protein expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

19 March 2017

Understanding alternative splicing: towards a cellular code

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

7 April 2017

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

7 April 2017

Lipoprotein receptors in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

Intronic variants in the dopa decarboxylase (DDC) gene are associated with smoking behavior in European-Americans and African-Americans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

The impact of our genes: consequences of the apolipoprotein E polymorphism in Alzheimer disease and multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

Method of predicting splice sites based on signal interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

Normal and abnormal mechanisms of gene splicing and relevance to inherited skin diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

The gonadotropin connection in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

Mutations in human gonadotropin and gonadotropin-receptor genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

Estrogens, progestins, menopause and neurodegeneration: basic and clinical studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

Low free testosterone is an independent risk factor for Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

Genetics, statistics and human disease: analytical retooling for complexity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

The current status of Alzheimer's disease genetics: what do we tell the patients?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

The Ubiquitous Nature of Epistasis in Determining Susceptibility to Common Human Diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

PyPop: a software framework for population genomics: analyzing large-scale multi-locus genotype data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

New strategies for identifying gene-gene interactions in hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

The number of trait loci in late-onset Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

A simulation study of the number of events per variable in logistic regression analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

Gender difference in apolipoprotein E-associated risk for familial Alzheimer disease: a possible clue to the higher incidence of Alzheimer disease in women.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

Novel presence of luteinizing hormone/human chorionic gonadotropin (hCG) receptors and the down-regulating action of hCG on gonadotropin-releasing hormone gene expression in immortalized hypothalamic GT1-7 neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

12 September 2017

A novel Ala(-3)Thr mutation in the signal peptide of human luteinizing hormone beta-subunit: potentiation of the inositol phosphate signalling pathway and attenuation of the adenylate cyclase pathway by recombinant variant hormone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

27 September 2017

The effect of reduction in cross-validation intervals on the performance of multifactor dimensionality reduction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

30 May 2018

Association study of the vascular endothelial growth factor gene with the risk of developing Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-9-37

21 January 2018

Lack of association of 5 SNPs in the vicinity of the insulin-degrading enzyme (IDE) gene with late-onset Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-9-37

21 January 2018

Association study and meta-analysis of low-density lipoprotein receptor related protein in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-9-37

21 January 2018

Estrogen receptor beta gene variants are associated with increased risk of Alzheimer's disease in women.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-9-37

21 January 2018

An association of elevated serum gonadotropin concentrations and Alzheimer disease?

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-9-37

21 January 2018

Peripheral and intracerebroventricular administration of human chorionic gonadotropin alters several hippocampus-associated behaviors in cycling female rats.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-9-37

21 January 2018

Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-9-37

21 January 2018

Absence of exon 10 of the human luteinizing hormone (LH) receptor impairs LH, but not human chorionic gonadotropin action.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-9-37

21 January 2018

An analysis paradigm for investigating multi-locus effects in complex disease: examination of three GABA receptor subunit genes on 15q11-q13 as risk factors for autistic disorder.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-9-37

21 January 2018

Gender and age modify the association between APOE and AD-related neuropathology.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-9-37

21 January 2018

Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-9-37

21 January 2018

ERCC4Associated with Breast Cancer Risk: A Two-Stage Case-Control Study Using High-throughput Genotyping

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-9-37

21 January 2018

Association of estrogen receptor alpha gene with Alzheimer's disease: a case-control study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

29 November 2018

Luteinizing hormone modulates cognition and amyloid-beta deposition in Alzheimer APP transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

29 November 2018

Estrogen replacement and risk of Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

29 November 2018

Elevated gonadotropin levels in patients with Alzheimer disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396156

29 November 2018

Leydig cell hypoplasia: cases with new mutations, new polymorphisms and cases without mutations in the luteinizing hormone receptor gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/18439297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular events involved in hormonal control of receptor-mediated endocytosis: regulation occurs at multiple sites in the low density lipoprotein pathway, including steps beyond the receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18439297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pituitary response to luteinizing hormone-releasing hormone in women with variant luteinizing hormone

1 reference

https://pubmed.ncbi.nlm.nih.gov/18439297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An apolipoprotein E synthetic peptide selectively modulates the transcription of the gene for rat ovarian theca and interstitial cell P450 17alpha-hydroxylase, C17-20 lyase

1 reference

https://pubmed.ncbi.nlm.nih.gov/18439297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of the androgen receptor CAG repeat polymorphism with Alzheimer's disease in men

1 reference

https://pubmed.ncbi.nlm.nih.gov/18439297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A limited repertoire of mutations of the luteinizing hormone (LH) receptor gene in familial and sporadic patients with male LH-independent precocious puberty

1 reference

https://pubmed.ncbi.nlm.nih.gov/18439297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of two point mutations in the gene coding luteinizing hormone (LH) beta-subunit, associated with immunologically anomalous LH variants

1 reference

https://pubmed.ncbi.nlm.nih.gov/18439297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combinations of variations in multiple genes are associated with hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/18439297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inpatients at risk of contact vaccinia from immunized health care workers

1 reference

https://api.crossref.org/works/10.1186%2F1471-2350-9-37

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1186/1471-2350-9-37

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/PMC/2396156

Dimensions Publication ID

0 references

release_ylondko2h5bdfmlj3zvkazrfl4

0 references

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/PMC/2396156

1 reference

Europe PubMed Central

23 December 2017

http://europepmc.org/abstract/PMC/2396156

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