(Q21423349)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

1 reference

14 February 2019

LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

transforming growth factor beta binding

IPI

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

14 February 2019

Molecular characterization and in situ localization of murine endoglin reveal that it is a transforming growth factor-beta binding protein of endothelial and stromal cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

transforming growth factor beta-activated receptor activity

IDA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

integral component of membrane

cell component

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

endothelial microparticle

IEA

1 reference

14 February 2019

CD36 participates in a signaling pathway that regulates ROS formation in murine VSMCs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

cell migration involved in endocardial cushion formation

biological process

1 reference

14 February 2019

Endoglin is dispensable for angiogenesis, but required for endocardial cushion formation in the midgestation mouse embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

venous blood vessel morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

14 February 2019

A murine model of hereditary hemorrhagic telangiectasia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

regulation of transforming growth factor beta receptor signaling pathway

IEA

3 references

14 February 2019

Endoglin, an ancillary TGFbeta receptor, is required for extraembryonic angiogenesis and plays a key role in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

3 references

14 February 2019

Endoglin, an ancillary TGFbeta receptor, is required for extraembryonic angiogenesis and plays a key role in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

14 February 2019

Loss of distinct arterial and venous boundaries in mice lacking endoglin, a vascular-specific TGFbeta coreceptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

smooth muscle tissue development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

branching involved in blood vessel morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

transforming growth factor beta receptor signaling pathway

1 reference

14 February 2019

Molecular characterization and in situ localization of murine endoglin reveal that it is a transforming growth factor-beta binding protein of endothelial and stromal cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

vascular associated smooth muscle cell development

IC

1 reference

14 February 2019

Endoglin is required for myogenic differentiation potential of neural crest stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

dorsal aorta morphogenesis

1 reference

14 February 2019

Loss of distinct arterial and venous boundaries in mice lacking endoglin, a vascular-specific TGFbeta coreceptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

regulation of cardiac muscle cell apoptotic process

1 reference

14 February 2019

Endoglin is required for myogenic differentiation potential of neural crest stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

epithelial to mesenchymal transition involved in endocardial cushion formation

1 reference

14 February 2019

Endoglin is dispensable for angiogenesis, but required for endocardial cushion formation in the midgestation mouse embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

1 reference

14 February 2019

Endoglin is dispensable for angiogenesis, but required for endocardial cushion formation in the midgestation mouse embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

atrial cardiac muscle tissue morphogenesis

1 reference

14 February 2019

Endoglin is required for myogenic differentiation potential of neural crest stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

endocardial cushion to mesenchymal transition

1 reference

14 February 2019

Loss of distinct arterial and venous boundaries in mice lacking endoglin, a vascular-specific TGFbeta coreceptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

endocardial cushion morphogenesis

negative regulation of gene expression

1 reference

14 February 2019

Loss of distinct arterial and venous boundaries in mice lacking endoglin, a vascular-specific TGFbeta coreceptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

outflow tract septum morphogenesis

1 reference

14 February 2019

Endoglin is required for myogenic differentiation potential of neural crest stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

positive regulation of vascular associated smooth muscle cell differentiation

IGI

1 reference

14 February 2019

Endoglin is required for myogenic differentiation potential of neural crest stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

cardiac atrium morphogenesis

1 reference

14 February 2019

Endoglin is dispensable for angiogenesis, but required for endocardial cushion formation in the midgestation mouse embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

ventricular trabecula myocardium morphogenesis

1 reference

14 February 2019

Endoglin is dispensable for angiogenesis, but required for endocardial cushion formation in the midgestation mouse embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

regulation of cell proliferation involved in heart morphogenesis

1 reference

14 February 2019

Endoglin is required for myogenic differentiation potential of neural crest stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

Endoglin is dispensable for angiogenesis, but required for endocardial cushion formation in the midgestation mouse embryo

sprouting angiogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

cardiac jelly development

1 reference

14 February 2019

Endoglin is dispensable for angiogenesis, but required for endocardial cushion formation in the midgestation mouse embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

atrioventricular canal morphogenesis

1 reference

14 February 2019

Endoglin is dispensable for angiogenesis, but required for endocardial cushion formation in the midgestation mouse embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

cardiac ventricle morphogenesis

1 reference

14 February 2019

Endoglin is dispensable for angiogenesis, but required for endocardial cushion formation in the midgestation mouse embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

negative regulation of transcription by RNA polymerase II

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

negative regulation of endothelial cell proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

positive regulation of systemic arterial blood pressure

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

extracellular matrix disassembly

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

negative regulation of nitric-oxide synthase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

negative regulation of pathway-restricted SMAD protein phosphorylation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis

1 reference

14 February 2019

Endoglin is required for myogenic differentiation potential of neural crest stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

positive regulation of gene expression

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

positive regulation of collagen biosynthetic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

extracellular matrix constituent secretion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63961

has part(s)

Zona pellucida domain

1 reference

stated in

InterPro Release 71.0