(Q28588583)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1905072

atrioventricular canal morphogenesis

1 reference

Gene Ontology release 2020-05-02

1 reference

GOA release 2020-03-11

1 reference

Aya Nomura-Kitabayashi

1

1 reference

31 January 2017

Gregory A. Anderson

2

1 reference

31 January 2017

Gillian Sleep

3

1 reference

31 January 2017

Jenny Mena

4

1 reference

31 January 2017

Amna Karabegovic

5

1 reference

31 January 2017

Sharon Karamath

6

1 reference

31 January 2017

Michelle Letarte

7

1 reference

31 January 2017

Mira C. Puri

Hereditary haemorrhagic telangiectasia: current views on genetics and mechanisms of disease

8

1 reference

31 January 2017

language of work or name

English

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publication date

1 November 2009

1 reference

31 January 2017

Developmental Biology

1 reference

31 January 2017

335

1 reference

31 January 2017

1

1 reference

31 January 2017

66–77

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31 January 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Generation of a floxed allele of the mouse Endoglin gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Heart valve development: endothelial cell signaling and differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Endoglin, an ancillary TGFbeta receptor, is required for extraembryonic angiogenesis and plays a key role in heart development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Double-outlet right ventricle and overriding tricuspid valve reflect disturbances of looping, myocardialization, endocardial cushion differentiation, and apoptosis in TGF-beta(2)-knockout mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

A murine model of hereditary hemorrhagic telangiectasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Endoglin-deficient mice, a unique model to study hereditary hemorrhagic telangiectasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Potential role of modifier genes influencing transforming growth factor-beta1 levels in the development of vascular defects in endoglin heterozygous mice with hereditary hemorrhagic telangiectasia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Temporal and distinct TGFbeta ligand requirements during mouse and avian endocardial cushion morphogenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Defective paracrine signalling by TGFbeta in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Compensatory signalling induced in the yolk sac vasculature by deletion of TGFbeta receptors in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

A field of myocardial-endocardial NFAT signaling underlies heart valve morphogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Chamber formation and morphogenesis in the developing mammalian heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Tgfbeta2 -/- Tgfbeta3 -/- double knockout mice display severe midline fusion defects and early embryonic lethality.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Primitive erythropoiesis from mesodermal precursors expressing VE-cadherin, PECAM-1, Tie2, endoglin, and CD34 in the mouse embryo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Tbx2 is essential for patterning the atrioventricular canal and for morphogenesis of the outflow tract during heart development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Gene-trap expression screening to identify endothelial-specific genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Endocardium is necessary for cardiomyocyte movement during heart tube assembly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Haemangioblast commitment is initiated in the primitive streak of the mouse embryo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Endoglin regulates nitric oxide-dependent vasodilatation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Reduced angiogenic responses in adult Endoglin heterozygous mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Tgfbeta signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Endoglin expression in early development is associated with vasculogenesis and angiogenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Specification of multipotential cardiovascular progenitor cells during embryonic stem cell differentiation and embryonic development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Hesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Essential role of developmentally activated hypoxia-inducible factor 1alpha for cardiac morphogenesis and function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Endoglin modulates cellular responses to TGF-beta 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Flow regulates arterial-venous differentiation in the chick embryo yolk sac.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Defective angiogenesis in mice lacking endoglin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Vascular remodeling of the mouse yolk sac requires hemodynamic force

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

A Titin mutation defines roles for circulation in endothelial morphogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Endoglin and Alk5 regulate epithelial-mesenchymal transformation during cardiac valve formation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Slug is a direct Notch target required for initiation of cardiac cushion cellularization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Endoglin null endothelial cells proliferate faster and are more responsive to transforming growth factor beta1 with higher affinity receptors and an activated Alk1 pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Endoglin is required for hemangioblast and early hematopoietic development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Cell biology of cardiac cushion development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Epithelial-mesenchymal cell transformation in the embryonic heart can be mediated, in part, by transforming growth factor beta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Transforming growth factor-beta 3 is required for secondary palate fusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Requirement for the TIE family of receptor tyrosine kinases in adult but not fetal hematopoiesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Distribution of endoglin in early human development reveals high levels on endocardial cushion tissue mesenchyme during valve formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Early fetal hypoxia leads to growth restriction and myocardial thinning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Bmp2 instructs cardiac progenitors to form the heart-valve-inducing field

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Invasion of mesenchyme into three-dimensional collagen gels: a regional and temporal analysis of interaction in embryonic heart tissue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Essential functions of Alk3 during AV cushion morphogenesis in mouse embryonic hearts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Loss of distinct arterial and venous boundaries in mice lacking endoglin, a vascular-specific TGFbeta coreceptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Signaling via the Tgf-beta type I receptor Alk5 in heart development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Bone morphogenetic protein-2 can mediate myocardial regulation of atrioventricular cushion mesenchymal cell formation in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

A role for endoglin in coupling eNOS activity and regulating vascular tone revealed in hereditary hemorrhagic telangiectasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Targeted disruption of Na+/Ca2+ exchanger gene leads to cardiomyocyte apoptosis and defects in heartbeat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Non-injection methods for the production of embryonic stem cell-embryo chimaeras

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016

Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.08.016