(Q21428218)

English

Caspase 12

mammalian protein found in Mus musculus

CASP-12
Casp12
caspase-12

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

caspase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08736

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08736

Death-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08736

Peptidase C14, caspase non-catalytic subunit p10, protein family

1 reference

based on heuristic

inferred from protein domain or family

Peptidase family C14A, cysteine active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

CARD domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Peptidase C14, p20 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Peptidase C14A, caspase catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Peptidase family C14A, His active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

protein binding

determination method

2 references

hydrolase activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

peptidase activity

determination method

3 references

14 February 2019

Comparative analysis of apoptosis and inflammation genes of mice and humans

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

14 February 2019

Comparative analysis of apoptosis and inflammation genes of mice and humans

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

cysteine-type endopeptidase activity involved in execution phase of apoptosis

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08736&geneProductId=UniProtKB:O08736

determination method

cysteine-type endopeptidase activity involved in apoptotic process

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

protease binding

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

endopeptidase activity

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

cysteine-type peptidase activity

determination method

3 references

cysteine-type endopeptidase activity

determination method

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

14 February 2019

An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

cysteine-type endopeptidase activity involved in apoptotic signaling pathway

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

NLRP3 inflammasome complex

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08736&geneProductId=UniProtKB:O08736

determination method

AIM2 inflammasome complex

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08736&geneProductId=UniProtKB:O08736

determination method

IPAF inflammasome complex

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08736&geneProductId=UniProtKB:O08736

determination method

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

intracellular membrane-bounded organelle

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

biological process

regulation of apoptotic process

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

self proteolysis

determination method

1 reference

14 February 2019

An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

endoplasmic reticulum unfolded protein response

determination method

1 reference

14 February 2019

Perk is essential for translational regulation and cell survival during the unfolded protein response

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

regulation of inflammatory response

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08736&geneProductId=UniProtKB:O08736

determination method

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

determination method

4 references

14 February 2019

No death without life: vital functions of apoptotic effectors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

14 February 2019

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

14 February 2019

Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

14 February 2019

An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

execution phase of apoptosis

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

determination method

5 references

14 February 2019

Comparative analysis of apoptosis and inflammation genes of mice and humans

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

14 February 2019

Comparative analysis of apoptosis and inflammation genes of mice and humans

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

protein autoprocessing

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

positive regulation of apoptotic process

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

intrinsic apoptotic signaling pathway

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

apoptotic process

determination method

3 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

14 February 2019

Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

activation of cysteine-type endopeptidase activity involved in apoptotic process

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

positive regulation of striated muscle cell apoptotic process

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08736

determination method

Peptidase C14, p20 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08736

Peptidase family C14A, His active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08736

Peptidase family C14A, cysteine active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08736

Peptidase C14A, caspase catalytic domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08736

Peptidase C14, caspase non-catalytic subunit p10

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08736

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O08736

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000027009

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000027009

ENSMUSP00000121565

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000121565

ENSMUSP00000122201

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000122201

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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