(Q21494878)

http://www.ebi.ac.uk/interpro/protein/Q60875

PH-like domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q60875

pleckstrin homology domain, protein family

1 reference

Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, protein family

1 reference

ARHGEF2, PH domain, protein family

1 reference

Dbl homology (DH) domain, protein family

1 reference

guanyl-nucleotide exchange factor activity

1 reference

25 May 2022

1 reference

25 May 2022

2 references

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

4 references

14 February 2019

Calpain-6, a microtubule-stabilizing protein, regulates Rac1 activity and cell motility through interaction with GEF-H1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

GEFH1 binds ASAP1 and regulates podosome formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

bicellular tight junction

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

1 reference

14 February 2019

The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

1 reference

14 February 2019

The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

1 reference

14 February 2019

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

1 reference

14 February 2019

GEFH1 binds ASAP1 and regulates podosome formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

protein-containing complex

IDA

3 references

glutamatergic synapse

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60875&geneProductId=UniProtKB:Q60875

postsynaptic density, intracellular component

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60875&geneProductId=UniProtKB:Q60875

intracellular signal transduction

biological process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

actin filament organization

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

immune system process

1 reference

14 February 2019

negative regulation of neurogenesis

1 reference

14 February 2019

Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

cellular response to muramyl dipeptide

3 references

negative regulation of microtubule depolymerization

3 references

positive regulation of NF-kappaB transcription factor activity

3 references

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

establishment of mitotic spindle orientation

IDA

1 reference

14 February 2019

Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

positive regulation of interleukin-6 production

IMP

3 references

positive regulation of tumor necrosis factor production

3 references

positive regulation of peptidyl-tyrosine phosphorylation

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

innate immune response

1 reference

14 February 2019

positive regulation of transcription by RNA polymerase II

3 references

negative regulation of podosome assembly

1 reference

14 February 2019

GEFH1 binds ASAP1 and regulates podosome formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

positive regulation of neuron migration

IMP

1 reference

14 February 2019

Homozygous ARHGEF2 mutation causes intellectual disability and midbrain-hindbrain malformation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

multicellular organism development

IMP

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

nervous system development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

positive regulation of neuron differentiation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

Homozygous ARHGEF2 mutation causes intellectual disability and midbrain-hindbrain malformation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

asymmetric neuroblast division

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

Homozygous ARHGEF2 mutation causes intellectual disability and midbrain-hindbrain malformation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60875