(Q21494983)

Helix-loop-helix DNA-binding domain superfamily

English

part of

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28574

Protein max

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28574

Myc-type, basic helix-loop-helix (bHLH) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

4 references

14 February 2019

c-Myc regulates transcriptional pause release

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

The C. elegans MDL-1 and MXL-1 proteins can functionally substitute for vertebrate MAD and MAX

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

A novel role for cardiac ankyrin repeat protein Ankrd1/CARP as a co-activator of the p53 tumor suppressor protein

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

protein dimerization activity

IPI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

protein homodimerization activity

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

DNA-binding transcription repressor activity, RNA polymerase II-specific

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

DNA-binding transcription factor activity

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

sequence-specific DNA binding

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

protein-containing complex binding

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

protein heterodimerization activity

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

14 February 2019

Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

RNA polymerase II general transcription initiation factor activity

1 reference

5 June 2018

Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

RNA polymerase II transcription regulatory region sequence-specific DNA binding

3 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

RNA polymerase II general transcription initiation factor activity

4 references

10 September 2018

Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

7 November 2018

Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

DNA-binding transcription repressor activity, RNA polymerase II-specific

8 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

DNA-binding transcription repressor activity, RNA polymerase II-specific

3 references

DNA-binding transcription factor activity

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

5 June 2018

The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

3 references

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

RNA polymerase II transcription regulator complex

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

transcription, DNA-templated

biological process

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

positive regulation of transcription by RNA polymerase II

1 reference

5 June 2018

Mga, a dual-specificity transcription factor that interacts with Max and contains a T-domain DNA-binding motif

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

negative regulation of transcription by RNA polymerase II

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

regulation of transcription, DNA-templated

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

negative regulation of gene expression

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

protein-containing complex assembly

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

cellular response to starvation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

response to organonitrogen compound

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

positive regulation of transcription by RNA polymerase II

response to axon injury

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

neuron apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

retina development in camera-type eye

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

cellular response to peptide hormone stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28574

transcription by RNA polymerase II

1 reference

7 November 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28574&geneProductId=UniProtKB:P28574

Myc-type, basic helix-loop-helix (bHLH) domain

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28574

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

1 reference

1 reference

20 March 2016

1 reference

20 March 2016

1 reference

20 March 2016