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c-Myc regulates transcriptional pause release
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scholarly article
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title
c-Myc regulates transcriptional pause release
(English)
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main subject
Myelocytomatosis oncogene
1 reference
stated in
GOA release 2020-03-11
Cyclin-dependent kinase 9 (CDC2-related kinase)
1 reference
stated in
GOA release 2020-03-11
Max protein
1 reference
stated in
GOA release 2020-03-11
Cyclin T1
1 reference
stated in
GOA release 2020-03-11
author
Ryan Flynn
series ordinal
4
object named as
Ryan A Flynn
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Richard A. Young
series ordinal
8
object named as
Richard A Young
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author name string
Peter B Rahl
series ordinal
1
0 references
Charles Y Lin
series ordinal
2
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Amy C Seila
series ordinal
3
0 references
Scott McCuine
series ordinal
5
0 references
Christopher B Burge
series ordinal
6
0 references
Phillip A Sharp
series ordinal
7
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language of work or name
English
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publication date
30 April 2010
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published in
Cell
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volume
141
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page(s)
432-45
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issue
3
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cites work
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DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs
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c-Myc recruits P-TEFb for transcription, cellular proliferation and apoptosis
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Diversified transcription initiation complexes expand promoter selectivity and tissue-specific gene expression
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7 April 2017
NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation
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7 April 2017
Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
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7 April 2017
5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II
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7 April 2017
The transition from transcriptional initiation to elongation
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The landscape of somatic copy-number alteration across human cancers
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Pre-mRNA processing reaches back to transcription and ahead to translation
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7 April 2017
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7 April 2017
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7 April 2017
Phosphorylation of serine 2 within the RNA polymerase II C-terminal domain couples transcription and 3' end processing
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Reflecting on 25 years with MYC.
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Database for mRNA half-life of 19 977 genes obtained by DNA microarray analysis of pluripotent and differentiating mouse embryonic stem cells
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27 September 2017
Myc's broad reach
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27 September 2017
Poised RNA polymerase II gives pause for thought
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Poised polymerases: on your mark...get set...go!
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Drosophila Pgc protein inhibits P-TEFb recruitment to chromatin in primordial germ cells
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27 September 2017
RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes.
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Improved low molecular weight Myc-Max inhibitors
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27 September 2017
Dissecting Oct3/4-regulated gene networks in embryonic stem cells by expression profiling
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27 September 2017
Tax interacts with P-TEFb in a novel manner to stimulate human T-lymphotropic virus type 1 transcription
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Drosophila Paf1 modulates chromatin structure at actively transcribed genes.
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27 September 2017
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27 September 2017
Low molecular weight inhibitors of Myc-Max interaction and function
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27 September 2017
NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila
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27 September 2017
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27 September 2017
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27 September 2017
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High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation
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RNA polymerase II interacts with the promoter region of the noninduced hsp70 gene in Drosophila melanogaster cells
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27 September 2017
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27 September 2017
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P-TEFb is critical for the maturation of RNA polymerase II into productive elongation in vivo
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30 May 2018
Myc recruits P-TEFb to mediate the final step in the transcriptional activation of the cad promoter
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30 May 2018
NF-kappaB binds P-TEFb to stimulate transcriptional elongation by RNA polymerase II.
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30 May 2018
Transcriptionally repressed germ cells lack a subpopulation of phosphorylated RNA polymerase II in early embryos of Caenorhabditis elegans and Drosophila melanogaster.
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30 May 2018
Purification of P-TEFb, a transcription factor required for the transition into productive elongation.
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30 May 2018
The RNA polymerase II molecule at the 5' end of the uninduced hsp70 gene of D. melanogaster is transcriptionally engaged.
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30 May 2018
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28 November 2018
P-TEFb is a crucial co-factor for Myc transactivation.
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28 November 2018
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28 November 2018
P-TEFb-mediated phosphorylation of hSpt5 C-terminal repeats is critical for processive transcription elongation
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28 November 2018
LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism.
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https://api.crossref.org/works/10.1016%2FJ.CELL.2010.03.030
retrieved
7 January 2021
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inferred from DOI database lookup
Core transcriptional regulatory circuitry in human embryonic stem cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.03.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of developmental regulators by Polycomb in human embryonic stem cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.03.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural rationale for the coupled binding and unfolding of the c-Myc oncoprotein by small molecules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.03.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.03.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.03.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.03.030
retrieved
7 January 2021
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Chromatin immunoprecipitation and microarray-based analysis of protein location
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.03.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Breaking barriers to transcription elongation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.03.030
retrieved
7 January 2021
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MYC-dependent regulation and prognostic role of CIP2A in gastric cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.03.030
retrieved
7 January 2021
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inferred from DOI database lookup
Identification of multiple cyclin subunits of human P-TEFb
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.03.030
retrieved
7 January 2021
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inferred from DOI database lookup
NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.03.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.03.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.03.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional regulation of survivin by c-Myc in BCR/ABL-transformed cells: implications in anti-leukaemic strategy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.03.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-Myc and Rel/NF-kappaB are the two master transcriptional systems activated in the latency III program of Epstein-Barr virus-immortalized B cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.03.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.03.030
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene function in early mouse embryonic stem cell differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.03.030
retrieved
7 January 2021
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Identifiers
DOI
10.1016/J.CELL.2010.03.030
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1044286
OpenCitations bibliographic resource ID
1044286
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1044286
PMCID
2864022
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1044286
PubMed ID
20434984
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1044286
ResearchGate publication ID
43534012
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