(Q21495664)

WD40-repeat-containing domain superfamily

1 reference

F-box-like domain superfamily

1 reference

F-box protein

1 reference

D domain of beta-TrCP, protein family

1 reference

WD40 repeat, protein family

1 reference

WD40 repeat, conserved site, protein family

1 reference

G-protein beta WD-40 repeat, protein family

1 reference

protein dimerization activity

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

protein phosphorylated amino acid binding

1 reference

14 February 2019

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

7 references

14 February 2019

Dual regulation of the transcriptional activity of Nrf1 by β-TrCP- and Hrd1-dependent degradation mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

14 February 2019

Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

14 February 2019

The role of {beta}-TrCP1 and {beta}-TrCP2 in circadian rhythm generation by mediating degradation of clock protein PER2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

14 February 2019

Multiple isoforms of beta-TrCP display differential activities in the regulation of Wnt signaling

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

14 February 2019

Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

14 February 2019

Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

14 February 2019

TAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

ubiquitin-protein transferase activity

IPI

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3ULA2&geneProductId=UniProtKB:Q3ULA2

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3ULA2&geneProductId=UniProtKB:Q3ULA2

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3ULA2&geneProductId=UniProtKB:Q3ULA2

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q3ULA2&geneProductId=UniProtKB:Q3ULA2

3 references

ubiquitin protein ligase activity

3 references

ubiquitin-protein transferase activity

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

SCF ubiquitin ligase complex

TAS

3 references

regulation of proteasomal protein catabolic process

1 reference

14 February 2019

Inhibition of microtubule assembly in osteoblasts stimulates bone morphogenetic protein 2 expression and bone formation through transcription factor Gli2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

mammary gland epithelial cell proliferation

1 reference

14 February 2019

Role of F-box protein betaTrcp1 in mammary gland development and tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

branching involved in mammary gland duct morphogenesis

1 reference

14 February 2019

Role of F-box protein betaTrcp1 in mammary gland development and tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

regulation of canonical Wnt signaling pathway

1 reference

14 February 2019

Multiple isoforms of beta-TrCP display differential activities in the regulation of Wnt signaling

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

cellular response to organic cyclic compound

1 reference

14 February 2019

Inhibition of microtubule assembly in osteoblasts stimulates bone morphogenetic protein 2 expression and bone formation through transcription factor Gli2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

protein dephosphorylation

1 reference

14 February 2019

The role of {beta}-TrCP1 and {beta}-TrCP2 in circadian rhythm generation by mediating degradation of clock protein PER2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

Wnt signaling pathway

1 reference

14 February 2019

Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo

regulation of cell cycle

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

positive regulation of transcription, DNA-templated

1 reference

14 February 2019

The role of {beta}-TrCP1 and {beta}-TrCP2 in circadian rhythm generation by mediating degradation of clock protein PER2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

protein catabolic process

1 reference

14 February 2019

Impaired degradation of inhibitory subunit of NF-kappa B (I kappa B) and beta-catenin as a result of targeted disruption of the beta-TrCP1 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

positive regulation of circadian rhythm

1 reference

14 February 2019

The role of {beta}-TrCP1 and {beta}-TrCP2 in circadian rhythm generation by mediating degradation of clock protein PER2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

regulation of I-kappaB kinase/NF-kappaB signaling

1 reference

14 February 2019

Impaired degradation of inhibitory subunit of NF-kappa B (I kappa B) and beta-catenin as a result of targeted disruption of the beta-TrCP1 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

negative regulation of transcription, DNA-templated

protein destabilization

3 references

3 references

regulation of circadian rhythm

3 references

protein ubiquitination

ISO

ubiquitin-dependent protein catabolic process

3 references

3 references

proteasome-mediated ubiquitin-dependent protein catabolic process

3 references

positive regulation of proteolysis

3 references

protein polyubiquitination

3 references

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

1 reference

14 February 2019

Dual regulation of the transcriptional activity of Nrf1 by β-TrCP- and Hrd1-dependent degradation mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q3ULA2

has part(s)

D domain of beta-TrCP

1 reference

WD40 repeat

1 reference

G-protein beta WD-40 repeat

1 reference

WD40 repeat, conserved site

1 reference

F-box domain

1 reference