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Impaired degradation of inhibitory subunit of NF-kappa B (I kappa B) and beta-catenin as a result of targeted disruption of the beta-TrCP1 gene
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
12843402
retrieved
24 January 2017
title
Impaired degradation of inhibitory subunit of NF-kappa B (I kappa B) and beta-catenin as a result of targeted disruption of the beta-TrCP1 gene
(English)
1 reference
stated in
PubMed
PubMed ID
12843402
retrieved
24 January 2017
main subject
Beta-transducin repeat containing protein
1 reference
stated in
GOA release 2020-03-11
NF-κB
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based on heuristic
inferred from title
author name string
Keiko Nakayama
series ordinal
1
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stated in
PubMed
PubMed ID
12843402
retrieved
24 January 2017
Shigetsugu Hatakeyama
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
12843402
retrieved
24 January 2017
Shun-ichiro Maruyama
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
12843402
retrieved
24 January 2017
Akira Kikuchi
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
12843402
retrieved
24 January 2017
Kazunori Onoé
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
12843402
retrieved
24 January 2017
Robert A. Good
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
12843402
retrieved
24 January 2017
Keiichi I. Nakayama
series ordinal
7
1 reference
stated in
PubMed
PubMed ID
12843402
retrieved
24 January 2017
language of work or name
English
0 references
publication date
22 July 2003
1 reference
stated in
PubMed
PubMed ID
12843402
retrieved
24 January 2017
published in
Proceedings of the National Academy of Sciences of the United States of America
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stated in
PubMed
PubMed ID
12843402
retrieved
24 January 2017
volume
100
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stated in
PubMed
PubMed ID
12843402
retrieved
24 January 2017
page(s)
8752–8757
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stated in
PubMed
PubMed ID
12843402
retrieved
24 January 2017
issue
15
1 reference
stated in
PubMed
PubMed ID
12843402
retrieved
24 January 2017
cites work
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Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses
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Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication
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19 March 2017
beta-TrCP mediates the signal-induced ubiquitination of IkappaBbeta
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PubMed Central
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19 March 2017
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Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34
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ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity
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19 March 2017
Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha
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19 March 2017
An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin
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19 March 2017
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase
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19 March 2017
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
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19 March 2017
The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.
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Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP
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19 March 2017
The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro
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19 March 2017
Identification of the receptor component of the IkappaBalpha-ubiquitin ligase
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The ubiquitin system
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PubMed Central
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19 March 2017
Identification of c-MYC as a target of the APC pathway
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A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p
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19 March 2017
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19 March 2017
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19 March 2017
SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box
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19 March 2017
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The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
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PubMed Central
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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
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Ubiquitin-mediated proteolysis: biological regulation via destruction
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Molecular dissection of the interactions among IkappaBalpha, FWD1, and Skp1 required for ubiquitin-mediated proteolysis of IkappaBalpha
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166385
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29 September 2017
Common pathway for the ubiquitination of IkappaBalpha, IkappaBbeta, and IkappaBepsilon mediated by the F-box protein FWD1.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166385
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29 September 2017
Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166385
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29 September 2017
The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166385
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29 September 2017
Cytoskeletal reorganization by soluble Wnt-3a protein signalling
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29 September 2017
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29 September 2017
Signal transduction through NF-kappa B.
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2 June 2018
Fission yeast WD-repeat protein pop1 regulates genome ploidy through ubiquitin-proteasome-mediated degradation of the CDK inhibitor Rum1 and the S-phase initiator Cdc18.
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PubMed Central
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2 June 2018
Inducible degradation of IkappaBalpha by the proteasome requires interaction with the F-box protein h-betaTrCP.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1073%2FPNAS.1133216100
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21 January 2018
Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb.
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21 January 2018
p25rum1 orders S phase and mitosis by acting as an inhibitor of the p34cdc2 mitotic kinase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12843402
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
In vivo and in vitro recruitment of an IkappaBalpha-ubiquitin ligase to IkappaBalpha phosphorylated by IKK, leading to ubiquitination
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12843402
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.1133216100
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ADS bibcode
2003PNAS..100.8752N
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PMCID
166385
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PubMed ID
12843402
1 reference
stated in
PubMed
PubMed ID
12843402
retrieved
24 January 2017
ResearchGate publication ID
10677046
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