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Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
10790373
retrieved
24 January 2017
title
Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication
(English)
1 reference
stated in
PubMed
PubMed ID
10790373
retrieved
24 January 2017
main subject
S-phase kinase-associated protein 2
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GOA release 2020-03-11
author name string
K. Nakayama
series ordinal
1
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PubMed
PubMed ID
10790373
retrieved
24 January 2017
H. Nagahama
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2
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PubMed
PubMed ID
10790373
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24 January 2017
Y. A. Minamishima
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3
1 reference
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PubMed
PubMed ID
10790373
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24 January 2017
M. Matsumoto
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4
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PubMed
PubMed ID
10790373
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24 January 2017
I. Nakamichi
series ordinal
5
1 reference
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PubMed
PubMed ID
10790373
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24 January 2017
K. Kitagawa
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6
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PubMed
PubMed ID
10790373
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24 January 2017
M. Shirane
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7
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PubMed
PubMed ID
10790373
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24 January 2017
R. Tsunematsu
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8
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PubMed
PubMed ID
10790373
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24 January 2017
T. Tsukiyama
series ordinal
9
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PubMed
PubMed ID
10790373
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24 January 2017
N. Ishida
series ordinal
10
1 reference
stated in
PubMed
PubMed ID
10790373
retrieved
24 January 2017
M. Kitagawa
series ordinal
11
1 reference
stated in
PubMed
PubMed ID
10790373
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24 January 2017
K. Nakayama
series ordinal
12
1 reference
stated in
PubMed
PubMed ID
10790373
retrieved
24 January 2017
S. Hatakeyama
series ordinal
13
1 reference
stated in
PubMed
PubMed ID
10790373
retrieved
24 January 2017
language of work or name
English
0 references
publication date
2 May 2000
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stated in
PubMed
PubMed ID
10790373
retrieved
24 January 2017
published in
The EMBO Journal
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stated in
PubMed
PubMed ID
10790373
retrieved
24 January 2017
volume
19
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stated in
PubMed
PubMed ID
10790373
retrieved
24 January 2017
page(s)
2069–2081
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PubMed
PubMed ID
10790373
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24 January 2017
issue
9
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PubMed
PubMed ID
10790373
retrieved
24 January 2017
cites work
SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
19 March 2017
Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
19 March 2017
Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
19 March 2017
Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
19 March 2017
Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
19 March 2017
p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
19 March 2017
Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
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19 March 2017
The ubiquitin system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
19 March 2017
Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
19 March 2017
A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
19 March 2017
F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
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19 March 2017
Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
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19 March 2017
Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
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19 March 2017
SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
19 March 2017
Chromosomal mapping of the genes for the human CDK2/cyclin A-associated proteins p19 (SKP1A and SKP1B) and p45 (SKP2)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
19 March 2017
Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
19 March 2017
The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
19 March 2017
p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
19 March 2017
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
7 April 2017
Whose end is destruction: cell division and the anaphase-promoting complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
7 April 2017
Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
7 April 2017
A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
7 April 2017
Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
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7 April 2017
A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
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7 April 2017
Structure and expression of the gene encoding mouse F-box protein, Fwd2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
29 September 2017
p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
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29 September 2017
Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
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29 September 2017
Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
29 September 2017
Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
29 September 2017
Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
29 September 2017
Deregulated cyclin E induces chromosome instability.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
2 June 2018
The role of cyclin E in cell proliferation, development and cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
2 June 2018
Fission yeast WD-repeat protein pop1 regulates genome ploidy through ubiquitin-proteasome-mediated degradation of the CDK inhibitor Rum1 and the S-phase initiator Cdc18.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
2 June 2018
Regulating protein degradation by ubiquitination.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
2 June 2018
Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305685
retrieved
2 June 2018
Identifiers
DOI
10.1093/EMBOJ/19.9.2069
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3886724
OpenCitations bibliographic resource ID
3886724
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3886724
PMCID
305685
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3886724
PubMed ID
10790373
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3886724
ResearchGate publication ID
232796418
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