(Q21498232)

Sox 7/17/18, central domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

High mobility group box domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Sox, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

sequence-specific DNA binding

1 reference

14 February 2019

Identification of two Sox17 messenger RNA isoforms, with and without the high mobility group box region, and their differential expression in mouse spermatogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

DNA-binding transcription factor activity

1 reference

14 February 2019

Sox7 and Sox17 are strain-specific modifiers of the lymphangiogenic defects caused by Sox18 dysfunction in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

DNA-binding transcription activator activity, RNA polymerase II-specific

1 reference

16 July 2018

A regulatory network controls nephrocan expression and midgut patterning

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

transcription coactivator activity

1 reference

14 February 2019

Identification of two Sox17 messenger RNA isoforms, with and without the high mobility group box region, and their differential expression in mouse spermatogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

protein heterodimerization activity

1 reference

14 February 2019

Deciphering the Sox-Oct partner code by quantitative cooperativity measurements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

1 reference

10 September 2018

SOX7 and SOX17 regulate the parietal endoderm-specific enhancer activity of mouse laminin alpha1 gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

16 July 2018

Deciphering the Sox-Oct partner code by quantitative cooperativity measurements

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

DNA-binding transcription factor activity, RNA polymerase II-specific

3 references

14 February 2019

Deciphering the Sox-Oct partner code by quantitative cooperativity measurements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

SOX7 and SOX17 regulate the parietal endoderm-specific enhancer activity of mouse laminin alpha1 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

9 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

16 July 2018

Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

16 July 2018

The primitive endoderm lineage of the mouse blastocyst: sequential transcription factor activation and regulation of differentiation by Sox17.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

16 July 2018

Sox17 influences the differentiation of respiratory epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

16 July 2018

Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

16 July 2018

Identification of two Sox17 messenger RNA isoforms, with and without the high mobility group box region, and their differential expression in mouse spermatogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

16 July 2018

Temporal reduction of LATS kinases in the early preimplantation embryo prevents ICM lineage differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

10 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

Identification of two Sox17 messenger RNA isoforms, with and without the high mobility group box region, and their differential expression in mouse spermatogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

Sox17 influences the differentiation of respiratory epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

Temporal reduction of LATS kinases in the early preimplantation embryo prevents ICM lineage differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

The primitive endoderm lineage of the mouse blastocyst: sequential transcription factor activation and regulation of differentiation by Sox17.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

3 references

14 February 2019

Depletion of definitive gut endoderm in Sox17-null mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

Expression and function of mouse Sox17 gene in the specification of gallbladder/bile-duct progenitors during early foregut morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

The primitive endoderm lineage of the mouse blastocyst: sequential transcription factor activation and regulation of differentiation by Sox17.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

regulation of embryonic development

1 reference

14 February 2019

Depletion of definitive gut endoderm in Sox17-null mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

positive regulation of protein catabolic process

1 reference

14 February 2019

Sox17 modulates Wnt3A/beta-catenin-mediated transcriptional activation of the Lef-1 promoter.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

stem cell fate specification

1 reference

14 February 2019

Contrasting effects of Sox17- and Sox18-sustained expression at the onset of blood specification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

positive regulation of skeletal muscle tissue development

1 reference

14 February 2019

Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

embryonic foregut morphogenesis

3 references

14 February 2019

ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

Sox17 regulates organ lineage segregation of ventral foregut progenitor cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

Sox17-dependent gene expression and early heart and gut development in Sox17-deficient mouse embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

embryonic organ development

1 reference

14 February 2019

Expression and function of mouse Sox17 gene in the specification of gallbladder/bile-duct progenitors during early foregut morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

endodermal digestive tract morphogenesis

1 reference

14 February 2019

Sox17-dependent gene expression and early heart and gut development in Sox17-deficient mouse embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

negative regulation of mesodermal cell fate specification

1 reference

14 February 2019

Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

inner cell mass cellular morphogenesis

1 reference

14 February 2019

The primitive endoderm lineage of the mouse blastocyst: sequential transcription factor activation and regulation of differentiation by Sox17.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

negative regulation of Wnt signaling pathway

Redundant roles of Sox17 and Sox18 in early cardiovascular development of mouse embryos

endocardium formation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

outflow tract morphogenesis

1 reference

14 February 2019

Redundant roles of Sox17 and Sox18 in early cardiovascular development of mouse embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

signal transduction involved in regulation of gene expression

1 reference

14 February 2019

ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

endodermal cell fate determination

1 reference

14 February 2019

Origin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

regulation of mesodermal cell fate specification

1 reference

14 February 2019

Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

negative regulation of transcription by RNA polymerase II

1 reference

16 July 2018

Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

Wnt signaling pathway

1 reference

14 February 2019

endocardial cell differentiation

IEA

1 reference

14 February 2019

Redundant roles of Sox17 and Sox18 in early cardiovascular development of mouse embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

regulation of cardiac cell fate specification

1 reference

14 February 2019

Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

transcription, DNA-templated

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

stem cell differentiation

IEA

1 reference

14 February 2019

Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

embryonic heart tube development

1 reference

14 February 2019

Redundant roles of Sox17 and Sox18 in early cardiovascular development of mouse embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

1 reference

16 July 2018

Redundant roles of Sox17 and Sox18 in postnatal angiogenesis in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

positive regulation of transcription, DNA-templated

3 references

14 February 2019

Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

Redundant roles of Sox17 and Sox18 in early cardiovascular development of mouse embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

Redundant roles of Sox17 and Sox18 in early cardiovascular development of mouse embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

common bile duct development

1 reference

14 February 2019

Expression and function of mouse Sox17 gene in the specification of gallbladder/bile-duct progenitors during early foregut morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

negative regulation of Wnt signaling pathway involved in heart development

1 reference

14 February 2019

Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

rostrocaudal neural tube patterning

1 reference

14 February 2019

Expression and function of mouse Sox17 gene in the specification of gallbladder/bile-duct progenitors during early foregut morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

positive regulation of gene expression

cardiogenic plate morphogenesis

1 reference

14 February 2019

Sox17-dependent gene expression and early heart and gut development in Sox17-deficient mouse embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

1 reference

14 February 2019

Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

embryonic heart tube morphogenesis

1 reference

14 February 2019

Sox17-dependent gene expression and early heart and gut development in Sox17-deficient mouse embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

1 reference

16 July 2018

Redundant roles of Sox17 and Sox18 in postnatal angiogenesis in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

1 reference

14 February 2019

Identification of two Sox17 messenger RNA isoforms, with and without the high mobility group box region, and their differential expression in mouse spermatogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

positive regulation of cell differentiation

regulation of stem cell division

1 reference

14 February 2019

Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

Expression and function of mouse Sox17 gene in the specification of gallbladder/bile-duct progenitors during early foregut morphogenesis

gall bladder development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

canonical Wnt signaling pathway

1 reference

14 February 2019

Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

regulation of cell differentiation

1 reference

14 February 2019

The primitive endoderm lineage of the mouse blastocyst: sequential transcription factor activation and regulation of differentiation by Sox17.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

cell migration involved in gastrulation

1 reference

14 February 2019

The primitive endoderm lineage of the mouse blastocyst: sequential transcription factor activation and regulation of differentiation by Sox17.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

regulation of stem cell proliferation

1 reference

14 February 2019

Contrasting effects of Sox17- and Sox18-sustained expression at the onset of blood specification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

positive regulation of transcription by RNA polymerase II

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

16 July 2018

Identification of two Sox17 messenger RNA isoforms, with and without the high mobility group box region, and their differential expression in mouse spermatogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

16 July 2018

Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61473&geneProductId=UniProtKB:Q61473

cellular response to leukemia inhibitory factor

1 reference

14 February 2019

miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

negative regulation of Wnt signaling pathway

1 reference

14 February 2019

Sox17 modulates Wnt3A/beta-catenin-mediated transcriptional activation of the Lef-1 promoter.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

negative regulation of canonical Wnt signaling pathway

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

positive regulation of transcription by RNA polymerase II

IBA

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

Identification of two Sox17 messenger RNA isoforms, with and without the high mobility group box region, and their differential expression in mouse spermatogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61473

1 reference

Sox 7/17/18, central domain

1 reference

stated in

High mobility group box domain

1 reference

stated in