(Q21499352)

Alpha crystallin/Heat shock protein

1 reference

Alpha-crystallin, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Alpha crystallin/Hsp20 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Alpha-crystallin B chain, ACD domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

4 references

8 April 2019

Mechanism of small heat shock protein function in vivo: a knock-in mouse model demonstrates that the R49C mutation in alpha A-crystallin enhances protein insolubility and cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

8 April 2019

Bioinformatics and cellular signaling

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

8 April 2019

Sinomenine activates astrocytic dopamine D2 receptors and alleviates neuroinflammatory injury via the CRYAB/STAT3 pathway after ischemic stroke in mice

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

8 April 2019

Cataract-linked γD-crystallin mutants have weak affinity to lens chaperones α-crystallins

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

structural constituent of eye lens

IPI

TAS

protein homodimerization activity

3 references

1 reference

8 April 2019

Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

1 reference

7 November 2018

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23927&geneProductId=UniProtKB:P23927

1 reference

8 April 2019

Cytoskeletal disruption and small heat shock protein translocation immediately after lengthening contractions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

1 reference

8 April 2019

Cytoskeletal disruption and small heat shock protein translocation immediately after lengthening contractions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

1 reference

8 April 2019

Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

1 reference

8 April 2019

Cytoskeletal disruption and small heat shock protein translocation immediately after lengthening contractions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

1 reference

8 April 2019

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

protein-containing complex

HDA

protein-containing complex

ISS

2 references

tubulin complex assembly

1 reference

8 April 2019

Alpha-crystallin expression affects microtubule assembly and prevents their aggregation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

IMP

1 reference

8 April 2019

Caspase-dependent secondary lens fiber cell disintegration in alphaA-/alphaB-crystallin double-knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

1 reference

8 April 2019

Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

apoptotic process involved in morphogenesis

IMP

1 reference

8 April 2019

Caspase-dependent secondary lens fiber cell disintegration in alphaA-/alphaB-crystallin double-knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

AlphaB-crystallin in lens development and muscle integrity: a gene knockout approach

IGI

muscle organ development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

negative regulation of gene expression

IGI

1 reference

8 April 2019

Up-regulation of tau, a brain microtubule-associated protein, in lens cortical fractions of aged alphaA-, alphaB-, and alphaA/B-crystallin knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

lens development in camera-type eye

IMP

1 reference

8 April 2019

Caspase-dependent secondary lens fiber cell disintegration in alphaA-/alphaB-crystallin double-knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

camera-type eye development

IGI

1 reference

8 April 2019

Morphological characterization of the Alpha A- and Alpha B-crystallin double knockout mouse lens

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

response to estradiol

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

negative regulation of apoptotic process

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

8 April 2019

Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

multicellular organism aging

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23927

negative regulation of transcription, DNA-templated

Alpha crystallin/Hsp20 domain

1 reference

Alpha-crystallin, N-terminal

1 reference

Alpha-crystallin B chain, ACD domain

1 reference