(Q28591145)

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Mechanism of small heat shock protein function in vivo: a knock-in mouse model demonstrates that the R49C mutation in alpha A-crystallin enhances protein insolubility and cell death

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PubMed publication ID

31 January 2017

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18056999%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Mechanism of small heat shock protein function in vivo: a knock-in mouse model demonstrates that the R49C mutation in alpha A-crystallin enhances protein insolubility and cell death (English)

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18056999%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Crystallin, alpha B

1 reference

GOA release 2020-03-11

Crystallin, alpha A

1 reference

GOA release 2020-03-11

Major intrinsic protein of lens fiber

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18056999%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18056999%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

author name string

Jing-hua Xi

1

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18056999%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Fang Bai

2

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18056999%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Julia Gross

3

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18056999%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

R Reid Townsend

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18056999%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

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publication date

5 December 2007

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Europe PubMed Central

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29 December 2019

number of pages

14

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

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29 December 2019

283

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PubMed publication ID

31 January 2017

Europe PubMed Central

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29 December 2019

9

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

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29 December 2019

5801-5814

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18056999%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

The human genome encodes 10 alpha-crystallin-related small heat shock proteins: HspB1-10

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Autosomal dominant congenital cataract associated with a missense mutation in the human alpha crystallin gene CRYAA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Cell death triggered by a novel mutation in the alphaA-crystallin gene underlies autosomal dominant cataract linked to chromosome 21q

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

A novel alphaB-crystallin mutation associated with autosomal dominant congenital lamellar cataract

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Lens epithelial cell differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Cell cycle regulation in the developing lens

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Ageing and vision: structure, stability and function of lens crystallins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Alpha-crystallin can function as a molecular chaperone

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Conformational and functional differences between recombinant human lens alphaA- and alphaB-crystallin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Crystallins in the eye: Function and pathology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

The molecular chaperone alphaA-crystallin enhances lens epithelial cell growth and resistance to UVA stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Reduced survival of lens epithelial cells in the alphaA-crystallin-knockout mouse

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Effect of site-directed mutagenesis of methylglyoxal-modifiable arginine residues on the structure and chaperone function of human alphaA-crystallin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Genealogy of the alpha-crystallin--small heat-shock protein superfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Cloning, expression, and chaperone-like activity of human alphaA-crystallin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

The R116C mutation in alpha A-crystallin diminishes its protective ability against stress-induced lens epithelial cell apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

A transgenic mouse model for human autosomal dominant cataract

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Unique and redundant connexin contributions to lens development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Arginine 54 and Tyrosine 118 residues of {alpha}A-crystallin are crucial for lens formation and transparency

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Subregion- and cell type-restricted gene knockout in mouse brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Accurate mass-driven analysis for the characterization of protein phosphorylation. Study of the human Chk2 protein kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

A signaling role for the uncleaved form of alpha 6 integrin in differentiating lens fiber cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Identification of genes responsive to UV-A radiation in human lens epithelial cells using complementary DNA microarrays.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Fluorescence resonance energy transfer study of subunit exchange in human lens crystallins and congenital cataract crystallin mutants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

A positive charge preservation at position 116 of alpha A-crystallin is critical for its structural and functional integrity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Molecular basis of a progressive juvenile-onset hereditary cataract

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Alpha-crystallin expression affects microtubule assembly and prevents their aggregation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Crystallin {gamma}B-I4F mutant protein binds to {alpha}-crystallin and affects lens transparency

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Altered aggregation properties of mutant gamma-crystallins cause inherited cataract

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Alteration of protein-protein interactions of congenital cataract crystallin mutants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Lens differentiation in vertebrates. A review of cellular and molecular features

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Expression and regulation of alpha-, beta-, and gamma-crystallins in mammalian lens epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Caspase-dependent secondary lens fiber cell disintegration in alphaA-/alphaB-crystallin double-knockout mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

bFGF suppresses serum-deprivation-induced apoptosis in a human lens epithelial cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Coordinate signaling by Src and p38 kinases in the induction of cortical cataracts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Mitogen-activated protein kinases in apoptosis regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Suppression of CED-3-independent apoptosis by mitochondrial betaNAC in Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Stress-specific activation and repression of heat shock factors 1 and 2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Structural and functional changes in the alpha A-crystallin R116C mutant in hereditary cataracts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

alpha-Crystallin chaperone-like activity and membrane binding in age-related cataracts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Regulation of cadherin junctions during mouse submandibular gland development.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Loss of alpha3beta1 integrin function results in an altered differentiation program in the mouse submandibular gland

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

N-cadherin function is required for differentiation-dependent cytoskeletal reorganization in lens cells in vitro.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Transparency and non-refractive functions of crystallins--a proposal

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708704200

21 January 2018

Identifiers

10.1074/JBC.M708704200

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18056999%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18056999%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

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