(Q21979847)

Histone deacetylase domain superfamily

1 reference

Zinc finger, RING/FYVE/PHD-type

1 reference

Histone deacetylase family

1 reference

inferred from protein domain or family

histone deacetylases

1 reference

based on heuristic

Zinc finger, UBP-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

NAD-dependent histone deacetylase activity (H3-K14 specific)

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

histone deacetylase activity

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

Identification of components of the murine histone deacetylase 6 complex: link between acetylation and ubiquitination signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

Identification of a new family of higher eukaryotic histone deacetylases. Coordinate expression of differentiation-dependent chromatin modifiers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

1 reference

14 February 2019

HDAC6-p97/VCP controlled polyubiquitin chain turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

5 references

14 February 2019

CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

A novel GRK2/HDAC6 interaction modulates cell spreading and motility

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

tubulin deacetylase activity

IPI

4 references

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2V5&geneProductId=UniProtKB:Q9Z2V5

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2V5&geneProductId=UniProtKB:Q9Z2V5

16 September 2017

CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2V5&geneProductId=UniProtKB:Q9Z2V5

16 September 2017

HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2V5&geneProductId=UniProtKB:Q9Z2V5

1 reference

14 February 2019

HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

misfolded protein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

protein deacetylase activity

ISO

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2V5&geneProductId=UniProtKB:Q9Z2V5

tubulin deacetylase activity

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

Tau--an inhibitor of deacetylase HDAC6 function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

AMP Kinase Activation Alters Oxidant-Induced Stress Granule Assembly by Modulating Cell Signaling and Microtubule Organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

acetylspermidine deacetylase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

1 reference

14 February 2019

Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

1 reference

14 February 2019

CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo

cytoplasmic microtubule

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

1 reference

14 February 2019

Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

3 references

14 February 2019

In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

Identification of components of the murine histone deacetylase 6 complex: link between acetylation and ubiquitination signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

Microtubule deacetylases, SirT2 and HDAC6, in the nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

protein-containing complex

1 reference

14 February 2019

HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

3 references

regulation of transcription, DNA-templated

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2V5&geneProductId=UniProtKB:Q9Z2V5

mitochondrion localization

1 reference

14 February 2019

Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

protein polyubiquitination

1 reference

14 February 2019

Identification of components of the murine histone deacetylase 6 complex: link between acetylation and ubiquitination signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

regulation of fat cell differentiation

1 reference

14 February 2019

Regulation of adipogenesis by cytoskeleton remodelling is facilitated by acetyltransferase MEC-17-dependent acetylation of α-tubulin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

transcription, DNA-templated

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z2V5&geneProductId=UniProtKB:Q9Z2V5

negative regulation of microtubule depolymerization

protein deacetylation

3 references

1 reference

14 February 2019

In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

dendritic spine morphogenesis

1 reference

14 February 2019

Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

tubulin deacetylation

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

HDAC6-p97/VCP controlled polyubiquitin chain turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

regulation of establishment of protein localization

1 reference

14 February 2019

The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

1 reference

14 February 2019

HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

1 reference

14 February 2019

Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

histone H3 deacetylation

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

cellular response to misfolded protein

1 reference

14 February 2019

HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

positive regulation of mitophagy in response to mitochondrial depolarization

1 reference

14 February 2019

Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

IGI

chromatin organization

1 reference

14 February 2019

protein-containing complex disassembly

1 reference

14 February 2019

HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

positive regulation of peptidyl-serine phosphorylation

IGI

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

peptidyl-lysine deacetylation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

polyamine deacetylation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z2V5

ISS

spermidine deacetylation

1 reference

14 February 2019

ISS

has part(s)

Zinc finger, UBP-type

1 reference

Histone deacetylase domain

1 reference