(Q21981053)

Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1 reference

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine/threonine-protein kinase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

The murine Dyrk protein maps to chromosome 16, localizes to the nucleus, and can form multimers

protein self-association

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

6 references

8 April 2019

DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

Dyrk1A potentiates steroid hormone-induced transcription via the chromatin remodeling factor Arip4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

Regulation of RCAN1 protein activity by Dyrk1A protein-mediated phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

2 references

protein serine/threonine kinase activity

5 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61214&geneProductId=UniProtKB:Q61214

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61214&geneProductId=UniProtKB:Q61214

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61214&geneProductId=UniProtKB:Q61214

31 October 2017

DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61214&geneProductId=UniProtKB:Q61214

31 October 2017

Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactions

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61214&geneProductId=UniProtKB:Q61214

protein tyrosine kinase activity

identical protein binding

ISS

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

The murine Dyrk protein maps to chromosome 16, localizes to the nucleus, and can form multimers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

Regulation of RCAN1 protein activity by Dyrk1A protein-mediated phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

protein serine/threonine kinase activity

ISO

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

protein tyrosine kinase activity

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

cytoskeletal protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

The murine Dyrk protein maps to chromosome 16, localizes to the nucleus, and can form multimers

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

Form of dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A nonphosphorylated at tyrosine 145 and 147 is enriched in the nuclei of astroglial cells, adult hippocampal progenitors, and some cholinergic axon terminals.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

1 reference

14 January 2019

Form of dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A nonphosphorylated at tyrosine 145 and 147 is enriched in the nuclei of astroglial cells, adult hippocampal progenitors, and some cholinergic axon terminals.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61214&geneProductId=UniProtKB:Q61214

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

Intracellular distribution of differentially phosphorylated dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A).

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

1 reference

8 April 2019

Form of dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A nonphosphorylated at tyrosine 145 and 147 is enriched in the nuclei of astroglial cells, adult hippocampal progenitors, and some cholinergic axon terminals.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

1 reference

8 April 2019

Form of dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A nonphosphorylated at tyrosine 145 and 147 is enriched in the nuclei of astroglial cells, adult hippocampal progenitors, and some cholinergic axon terminals.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

ribonucleoprotein complex

1 reference

8 April 2019

Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

14 February 2019

Form of dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A nonphosphorylated at tyrosine 145 and 147 is enriched in the nuclei of astroglial cells, adult hippocampal progenitors, and some cholinergic axon terminals.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

Form of dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A nonphosphorylated at tyrosine 145 and 147 is enriched in the nuclei of astroglial cells, adult hippocampal progenitors, and some cholinergic axon terminals.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

positive regulation of protein deacetylation

biological process

1 reference

8 April 2019

Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

negative regulation of mRNA splicing, via spliceosome

1 reference

8 April 2019

Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

negative regulation of DNA damage response, signal transduction by p53 class mediator

IMP

1 reference

8 April 2019

Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

1 reference

8 April 2019

DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

peptidyl-tyrosine phosphorylation

IMP

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

peptidyl-threonine phosphorylation

1 reference

31 October 2017

Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactions

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61214&geneProductId=UniProtKB:Q61214

regulation of alternative mRNA splicing, via spliceosome

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61214&geneProductId=UniProtKB:Q61214

protein autophosphorylation

ISS

protein phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

ISS

protein phosphorylation

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

peptidyl-serine phosphorylation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

peptidyl-threonine phosphorylation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

negative regulation of microtubule polymerization

1 reference

8 April 2019

DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

peptidyl-tyrosine autophosphorylation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

Intracellular distribution of differentially phosphorylated dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A).

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

protein autophosphorylation

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214

serine/threonine-protein kinase, active site

has part(s)

1 reference

protein kinase domain

1 reference

protein kinase, ATP binding site

1 reference