(Q21985060)

Winged helix-like DNA-binding domain superfamily

1 reference

Winged helix DNA-binding domain superfamily

1 reference

Vertebrate heat shock transcription factor, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Heat shock factor (HSF)-type, DNA-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

DNA-binding transcription factor activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38532&geneProductId=UniProtKB:P38532

1 reference

14 February 2019

Identification of heat shock factor 1 molecular and cellular targets during embryonic and adult female meiosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

DNA-binding transcription repressor activity, RNA polymerase II-specific

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38532&geneProductId=UniProtKB:P38532

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38532&geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

Heat shock factor 2 is activated during mouse heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

heat shock protein binding

3 references

identical protein binding

3 references

protein self-association

3 references

chromatin DNA binding

3 references

sequence-specific DNA binding

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38532&geneProductId=UniProtKB:P38532

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38532&geneProductId=UniProtKB:P38532

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38532&geneProductId=UniProtKB:P38532

24 April 2018

Analysis of HSF4 binding regions reveals its necessity for gene regulation during development and heat shock response in mouse lenses

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38532&geneProductId=UniProtKB:P38532

protein heterodimerization activity

3 references

Hsp90 protein binding

3 references

translation elongation factor binding

3 references

promoter-specific chromatin binding

3 references

RNA polymerase II cis-regulatory region sequence-specific DNA binding

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38532&geneProductId=UniProtKB:P38532

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38532&geneProductId=UniProtKB:P38532

24 April 2018

Interaction of HSF1 and HSF2 with the Hspa1b promoter in mouse epididymal spermatozoa

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38532&geneProductId=UniProtKB:P38532

RNA polymerase II cis-regulatory region sequence-specific DNA binding

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

Interaction of HSF1 and HSF2 with the Hspa1b promoter in mouse epididymal spermatozoa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

sequence-specific DNA binding

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

Analysis of HSF4 binding regions reveals its necessity for gene regulation during development and heat shock response in mouse lenses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

Heat shock factor 2 is activated during mouse heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

Early transcriptional activation of the hsp70.1 gene by osmotic stress in one-cell embryos of the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

1 reference

14 February 2019

Early transcriptional activation of the hsp70.1 gene by osmotic stress in one-cell embryos of the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

chromosome, centromeric region

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

6 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38532&geneProductId=UniProtKB:P38532

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38532&geneProductId=UniProtKB:P38532

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38532&geneProductId=UniProtKB:P38532

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38532&geneProductId=UniProtKB:P38532

24 April 2018

Interaction of HSF1 and HSF2 with the Hspa1b promoter in mouse epididymal spermatozoa

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38532&geneProductId=UniProtKB:P38532

24 April 2018

Heat shock factor 2 is activated during mouse heart development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38532&geneProductId=UniProtKB:P38532

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

microtubule organizing center

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

3 references

nuclear stress granule

3 references

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

perinuclear region of cytoplasm

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

3 references

ribonucleoprotein complex

3 references

protein-containing complex

1 reference

14 February 2019

HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

Heat shock factor 2 is activated during mouse heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

Interaction of HSF1 and HSF2 with the Hspa1b promoter in mouse epididymal spermatozoa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

cellular response to heat

biological process

regulation of transcription, DNA-templated

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

embryonic placenta development

1 reference

14 February 2019

HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

in utero embryonic development

1 reference

14 February 2019

HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

female meiotic nuclear division

1 reference

14 February 2019

Identification of heat shock factor 1 molecular and cellular targets during embryonic and adult female meiosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38532&geneProductId=UniProtKB:P38532

embryonic process involved in female pregnancy

1 reference

14 February 2019

HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

Analysis of HSF4 binding regions reveals its necessity for gene regulation during development and heat shock response in mouse lenses

protein phosphorylation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

response to lipopolysaccharide

1 reference

14 February 2019

HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

1 reference

14 February 2019

Essential requirement for both hsf1 and hsf2 transcriptional activity in spermatogenesis and male fertility

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

positive regulation of multicellular organism growth

IGI

1 reference

14 February 2019

HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

negative regulation of tumor necrosis factor production

1 reference

14 February 2019

HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

negative regulation of cell population proliferation

1 reference

14 February 2019

HSF4 is required for normal cell growth and differentiation during mouse lens development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

cellular response to nitroglycerin

IGI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

cellular response to L-glutamine

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

cellular response to potassium ion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

response to hypobaric hypoxia

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

response to organonitrogen compound

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

response to psychosocial stress

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

response to amino acid

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

response to organic cyclic compound

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

cellular response to lipopolysaccharide

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

negative regulation of transcription by RNA polymerase II

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

cellular response to DNA damage stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

positive regulation of transcription by RNA polymerase II

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

protein homooligomerization

3 references

positive regulation of transcription from RNA polymerase II promoter in response to heat stress

protein homotrimerization

3 references

cellular response to cadmium ion

3 references

positive regulation of mRNA polyadenylation

3 references

3 references

positive regulation of cell population proliferation

3 references

Unfolded Protein Response

3 references

regulation of protein heterodimerization activity

3 references

positive regulation of mitotic cell cycle

3 references

cellular response to copper ion

3 references

cellular response to gamma radiation

3 references

cellular response to diamide

3 references

regulation of cellular response to heat

3 references

cellular response to sodium arsenite

3 references

negative regulation of double-strand break repair via nonhomologous end joining

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

cellular response to heat

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

positive regulation of transcription from RNA polymerase II promoter in response to heat stress

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

positive regulation of cold-induced thermogenesis

1 reference

14 February 2019

Celastrol Protects against Obesity and Metabolic Dysfunction through Activation of a HSF1-PGC1α Transcriptional Axis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38532

Heat shock factor (HSF)-type, DNA-binding

has part(s)

1 reference

Vertebrate heat shock transcription factor, C-terminal domain

1 reference