Wikidata

(Q21985507)

English

Intraflagellar transport 88

mammalian protein found in Mus musculus

  • recessive polycystic kidney disease protein Tg737
  • transgene insert site 737, insertional mutation, polycystic kidney disease
  • TPR repeat protein 10
  • intraflagellar transport protein 88 homolog
  • intraflagellar transport 88 homolog
  • tetratricopeptide repeat protein 10
  • tetratricopeptide repeat domain 10
  • Ift88
  • tgN(Imorpk)737Rpw
In more languages
default for all languages
No label defined

No description defined

Statements

molecular function
cell component
intraciliary transport particle B
determination method or standard
IDA
5 references
retrieved
9 May 2019
stated in
TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella
GOA
curator
UniProt
UniProt protein ID
Q61371
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.
GOA
curator
UniProt
UniProt protein ID
Q61371
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
Interaction of mouse TTC30/DYF-1 with multiple intraflagellar transport complex B proteins and KIF17
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
Characterization of mouse IFT complex B
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
ciliary basal body
determination method or standard
IDA
ISO
5 references
retrieved
31 January 2018
stated in
The BBSome controls IFT assembly and turnaround in cilia
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371
determination method or standard
ISO
retrieved
31 January 2018
stated in
Ofd1, a human disease gene, regulates the length and distal structure of centrioles
GOA
curator
UniProt
UniProt protein ID
Q61371
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
31 January 2018
stated in
Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
31 January 2018
stated in
Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
31 January 2018
stated in
Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61371&geneProductId=UniProtKB:Q61371
determination method or standard
IDA
axoneme
determination method or standard
IDA
5 references
retrieved
9 May 2019
stated in
Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
Ciliary proteins link basal body polarization to planar cell polarity regulation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
Intraflagellar transport molecules in ciliary and nonciliary cells of the retina
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
cilium
determination method or standard
IDA
IEA
ISO
TAS
13 references
retrieved
9 May 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
TAS
retrieved
9 May 2019
stated in
The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
ISO
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61371
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IEA
retrieved
9 May 2019
stated in
Ofd1, a human disease gene, regulates the length and distal structure of centrioles
GOA
curator
UniProt
UniProt protein ID
Q61371
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals.
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
Primary cilia control hedgehog signaling during muscle differentiation and are deregulated in rhabdomyosarcoma
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
Characterization of mouse IFT complex B
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components
GOA
curator
Community Assessment of Community Annotation with Ontologies
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
centriole
determination method or standard
IBA
IDA
IEA
ISO
6 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
ISO
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61371
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IEA
retrieved
9 May 2019
stated in
Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages
GOA
curator
UniProt
UniProt protein ID
Q61371
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
Ofd1, a human disease gene, regulates the length and distal structure of centrioles
GOA
curator
UniProt
UniProt protein ID
Q61371
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals.
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IBA
ciliary basal body
determination method or standard
IBA
IDA
ISO
6 references
retrieved
9 May 2019
stated in
The BBSome controls IFT assembly and turnaround in cilia
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
ISO
retrieved
9 May 2019
stated in
Ofd1, a human disease gene, regulates the length and distal structure of centrioles
GOA
curator
UniProt
UniProt protein ID
Q61371
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IBA
biological process
embryonic digit morphogenesis
determination method or standard
IGI
IMP
6 references
retrieved
9 May 2019
stated in
Loss of the Tg737 protein results in skeletal patterning defects
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IMP
retrieved
9 May 2019
stated in
Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IMP
retrieved
9 May 2019
stated in
Analysis of mouse embryonic patterning and morphogenesis by forward genetics
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IMP
retrieved
9 May 2019
stated in
Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IMP
retrieved
9 May 2019
stated in
A crucial role for primary cilia in cortical morphogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IMP
retrieved
9 May 2019
stated in
Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IGI
smoothened signaling pathway
determination method or standard
IGI
IMP
6 references
retrieved
9 May 2019
stated in
Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IMP
retrieved
9 May 2019
stated in
A crucial role for primary cilia in cortical morphogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IMP
retrieved
9 May 2019
stated in
BBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IMP
retrieved
9 May 2019
stated in
Role of epidermal primary cilia in the homeostasis of skin and hair follicles
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IMP
retrieved
9 May 2019
stated in
The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IMP
retrieved
9 May 2019
stated in
Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IGI
non-motile cilium assembly
determination method or standard
IBA
IMP
5 references
retrieved
9 May 2019
stated in
Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IMP
retrieved
9 May 2019
stated in
Primary cilia dynamics instruct tissue patterning and repair of corneal endothelium
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IMP
retrieved
9 May 2019
stated in
Primary cilia control hedgehog signaling during muscle differentiation and are deregulated in rhabdomyosarcoma
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IMP
retrieved
9 May 2019
stated in
A role for the primary cilium in Notch signaling and epidermal differentiation during skin development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IMP
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61371
determination method or standard
IBA

Identifiers

 
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