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The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
22689656
retrieved
24 January 2017
title
The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking
(English)
1 reference
stated in
PubMed
PubMed ID
22689656
retrieved
24 January 2017
main subject
protein structure
0 references
Smoothened, frizzled class receptor
1 reference
stated in
GOA release 2020-03-11
Dynein cytoplasmic 2 heavy chain 1
1 reference
stated in
GOA release 2020-03-11
ADP-ribosylation factor-like 13B
1 reference
stated in
GOA release 2020-03-11
Intraflagellar transport 88
1 reference
stated in
GOA release 2020-03-11
WD repeat domain 19
1 reference
stated in
GOA release 2020-03-11
Intraflagellar transport 122
1 reference
stated in
GOA release 2020-03-11
GLI-Kruppel family member GLI2
1 reference
stated in
GOA release 2020-03-11
membrane protein
1 reference
based on heuristic
inferred from title
author
Carol Wicking
object named as
Carol Wicking
series ordinal
7
0 references
Jennifer L. Moran
object named as
Jennifer Moran
series ordinal
5
0 references
Kathryn V. Anderson
series ordinal
8
object named as
Kathryn V. Anderson
1 reference
stated in
PubMed
PubMed ID
22689656
retrieved
24 January 2017
author name string
Karel F. Liem
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
22689656
retrieved
24 January 2017
Alyson Ashe
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
22689656
retrieved
24 January 2017
Mu He
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
22689656
retrieved
24 January 2017
Peter Satir
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
22689656
retrieved
24 January 2017
David Beier
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
22689656
retrieved
24 January 2017
language of work or name
English
0 references
publication date
11 June 2012
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stated in
PubMed
PubMed ID
22689656
retrieved
24 January 2017
published in
Journal of Cell Biology
1 reference
stated in
PubMed
PubMed ID
22689656
retrieved
24 January 2017
volume
197
1 reference
stated in
PubMed
PubMed ID
22689656
retrieved
24 January 2017
issue
6
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stated in
PubMed
PubMed ID
22689656
retrieved
24 January 2017
page(s)
789–800
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stated in
PubMed
PubMed ID
22689656
retrieved
24 January 2017
cites work
Mainzer-Saldino syndrome is a ciliopathy caused by IFT140 mutations
1 reference
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PubMed Central
reference URL
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19 March 2017
Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies
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PubMed Central
reference URL
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19 March 2017
Subunit interactions and organization of the Chlamydomonas reinhardtii intraflagellar transport complex A proteins
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PubMed Central
reference URL
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19 March 2017
Ciliopathies with skeletal anomalies and renal insufficiency due to mutations in the IFT-A gene WDR19
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PubMed Central
reference URL
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19 March 2017
Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube
1 reference
stated in
PubMed Central
reference URL
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19 March 2017
Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
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19 March 2017
A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition
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PubMed Central
reference URL
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19 March 2017
Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases
1 reference
stated in
PubMed Central
reference URL
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19 March 2017
A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus
1 reference
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PubMed Central
reference URL
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19 March 2017
Complex interactions between genes controlling trafficking in primary cilia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
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19 March 2017
Mechanisms and functions of Hedgehog signalling across the metazoa
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
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19 March 2017
Human and mouse mutations in WDR35 cause short-rib polydactyly syndromes due to abnormal ciliogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
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19 March 2017
C14ORF179 encoding IFT43 is mutated in Sensenbrenner syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
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19 March 2017
Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
Exome sequencing identifies WDR35 variants involved in Sensenbrenner syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
The ciliary membrane
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in Caenorhabditis elegans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
Electron-tomographic analysis of intraflagellar transport particle trains in situ
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
Retrograde intraflagellar transport mutants identify complex A proteins with multiple genetic interactions in Chlamydomonas reinhardtii
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
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19 March 2017
Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
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19 March 2017
Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
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19 March 2017
Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
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19 March 2017
Making a grade: Sonic Hedgehog signalling and the control of neural cell fate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
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19 March 2017
Intraflagellar transport (IFT) role in ciliary assembly, resorption and signalling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
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19 March 2017
Intraflagellar transport, cilia, and mammalian Hedgehog signaling: analysis in mouse embryonic fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
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19 March 2017
THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
The graded response to Sonic Hedgehog depends on cilia architecture
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
Caenorhabditis elegans DYF-2, an orthologue of human WDR19, is a component of the intraflagellar transport machinery in sensory cilia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
Cilia and Hedgehog responsiveness in the mouse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
Analysis of mouse embryonic patterning and morphogenesis by forward genetics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
All mouse ventral spinal cord patterning by hedgehog is Gli dependent and involves an activator function of Gli3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
Hedgehog signalling in the mouse requires intraflagellar transport proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
The intraflagellar transport machinery of Chlamydomonas reinhardtii
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
An autosomal recessive polycystic kidney disease gene homolog is involved in intraflagellar transport in C. elegans ciliated sensory neurons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
Protein particles in Chlamydomonas flagella undergo a transport cycle consisting of four phases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
Altered neural cell fates and medulloblastoma in mouse patched mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
Tulp3 is a critical repressor of mouse hedgehog signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
19 March 2017
The primary cilium: a signalling centre during vertebrate development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
7 April 2017
Centrioles and the formation of rudimentary cilia by fibroblasts and smooth muscle cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
7 April 2017
TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
29 September 2017
Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
29 September 2017
IFT80, which encodes a conserved intraflagellar transport protein, is mutated in Jeune asphyxiating thoracic dystrophy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
29 September 2017
Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
29 September 2017
The DHC1b (DHC2) isoform of cytoplasmic dynein is required for flagellar assembly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
29 September 2017
Sonic-hedgehog-mediated proliferation requires the localization of PKA to the cilium base.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3373400
retrieved
2 June 2018
Type III adenylyl cyclase localizes to primary cilia throughout the adult mouse brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1083%2FJCB.201110049
retrieved
21 January 2018
Mouse Dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1083%2FJCB.201110049
retrieved
21 January 2018
Dissecting the Molecular Mechanisms of Intraflagellar Transport in Chlamydomonas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1083%2FJCB.201110049
retrieved
21 January 2018
Identifiers
DOI
10.1083/JCB.201110049
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1469353
OpenCitations bibliographic resource ID
1469353
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1469353
PMCID
3373400
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1469353
PubMed ID
22689656
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1469353
ResearchGate publication ID
225293464
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