Wikidata

(Q21985771)

English

Mediator complex subunit 1

mammalian protein found in Mus musculus

  • thyroid hormone receptor-associated protein complex 220 kDa component
  • TR-interacting protein 2
  • PPAR-binding protein
  • Med1
  • PBP
  • peroxisome proliferator-activated receptor-binding protein
  • Ppar binding protein
  • thyroid receptor-interacting protein 2
  • Trap220
  • TRIP-2
  • mediator of RNA polymerase II transcription subunit 1
In more languages

Statements

molecular function
protein binding
determination method
IPI
5 references
retrieved
8 April 2019
stated in
Distinct roles of the steroid receptor coactivator 1 and of MED1 in retinoid-induced transcription and cellular differentiation
GOA
curator
UniProt
UniProt protein ID
Q925J9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
IPI
retrieved
8 April 2019
stated in
The AF-1 domain of the orphan nuclear receptor NOR-1 mediates trans-activation, coactivator recruitment, and activation by the purine anti-metabolite 6-mercaptopurine
GOA
curator
UniProt
UniProt protein ID
Q925J9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
IPI
retrieved
8 April 2019
stated in
Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor
GOA
curator
UniProt
UniProt protein ID
Q925J9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
IPI
retrieved
8 April 2019
stated in
A positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machinery
GOA
curator
UniProt
UniProt protein ID
Q925J9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
IPI
retrieved
8 April 2019
stated in
The Med1 subunit of transcriptional mediator plays a central role in regulating CCAAT/enhancer-binding protein-beta-driven transcription in response to interferon-gamma
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
IPI
transcription coactivator activity
determination method
IDA
TAS
IEA
ISO
8 references
retrieved
8 April 2019
stated in
Deletion of PBP/PPARBP, the gene for nuclear receptor coactivator peroxisome proliferator-activated receptor-binding protein, results in embryonic lethality
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
TAS
retrieved
8 April 2019
stated in
Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
TAS
retrieved
8 April 2019
stated in
Differential expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) and its coactivators steroid receptor coactivator-1 and PPAR-binding protein PBP in the brown fat, urinary bladder, colon, and breast of the mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
ISO
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
IEA
retrieved
8 April 2019
stated in
Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
IDA
retrieved
8 April 2019
stated in
Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
IDA
retrieved
8 April 2019
stated in
Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
IDA
transcription coregulator activity
determination method
IBA
ISS
IEA
ISO
10 references
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q925J9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q925J9&geneProductId=UniProtKB:Q925J9
determination method
ISS
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q925J9&geneProductId=UniProtKB:Q925J9
determination method
ISO
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q925J9&geneProductId=UniProtKB:Q925J9
determination method
IEA
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q925J9&geneProductId=UniProtKB:Q925J9
determination method
IEA
retrieved
24 April 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q925J9&geneProductId=UniProtKB:Q925J9
determination method
IBA
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q925J9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
ISO
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
IBA
cell component
mediator complex
determination method
IDA
IEA
ISO
6 references
retrieved
16 July 2018
stated in
A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q925J9&geneProductId=UniProtKB:Q925J9
determination method
ISO
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q925J9&geneProductId=UniProtKB:Q925J9
determination method
IEA
retrieved
16 July 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q925J9&geneProductId=UniProtKB:Q925J9
determination method
IEA
retrieved
16 July 2018
stated in
ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q925J9&geneProductId=UniProtKB:Q925J9
determination method
IDA
retrieved
16 July 2018
stated in
The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q925J9&geneProductId=UniProtKB:Q925J9
determination method
IDA
retrieved
16 July 2018
stated in
Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q925J9&geneProductId=UniProtKB:Q925J9
determination method
IDA
mediator complex
determination method
IBA
IDA
IEA
ISO
6 references
retrieved
8 April 2019
stated in
A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
ISO
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
IEA
retrieved
8 April 2019
stated in
Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
IDA
retrieved
8 April 2019
stated in
The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q925J9
determination method
IBA
biological process
regulation of transcription, DNA-templated
determination method
IDA
TAS
IMP
IEA
5 references
retrieved
16 July 2018
stated in
Deletion of PBP/PPARBP, the gene for nuclear receptor coactivator peroxisome proliferator-activated receptor-binding protein, results in embryonic lethality
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q925J9&geneProductId=UniProtKB:Q925J9
determination method
TAS
retrieved
16 July 2018
stated in
Differential expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) and its coactivators steroid receptor coactivator-1 and PPAR-binding protein PBP in the brown fat, urinary bladder, colon, and breast of the mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q925J9&geneProductId=UniProtKB:Q925J9
determination method
TAS
retrieved
16 July 2018
stated in
Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q925J9&geneProductId=UniProtKB:Q925J9
determination method
IMP
retrieved
16 July 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q925J9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q925J9&geneProductId=UniProtKB:Q925J9
determination method
IEA
retrieved
16 July 2018
stated in
Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q925J9&geneProductId=UniProtKB:Q925J9
determination method
IDA

Identifiers

 
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