(Q28594740)

English

The AF-1 domain of the orphan nuclear receptor NOR-1 mediates trans-activation, coactivator recruitment, and activation by the purine anti-metabolite 6-mercaptopurine

scientific journal article

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scholarly article

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709428%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

The AF-1 domain of the orphan nuclear receptor NOR-1 mediates trans-activation, coactivator recruitment, and activation by the purine anti-metabolite 6-mercaptopurine (English)

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709428%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Nuclear receptor coactivator 3

1 reference

GOA release 2020-03-11

Nuclear receptor coactivator 1

1 reference

GOA release 2020-03-11

Mediator complex subunit 1

1 reference

GOA release 2020-03-11

K(lysine) acetyltransferase 2B

1 reference

GOA release 2020-03-11

E1A binding protein p300

1 reference

GOA release 2020-03-11

Nuclear receptor coactivator 2

1 reference

GOA release 2020-03-11

Nuclear receptor subfamily 4, group A, member 3

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

Jonathan Harris

2

1 reference

Europe PubMed Central

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2 November 2019

5

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2 November 2019

author name string

Grace Yan

3

2 references

31 January 2017

Europe PubMed Central

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2 November 2019

Peter Ordentlich

4

2 references

31 January 2017

Europe PubMed Central

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2 November 2019

K D Senali Abayratna Wansa

1

1 reference

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2 November 2019

language of work or name

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publication date

22 April 2003

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2 November 2019

Journal of Biological Chemistry

2 references

31 January 2017

Europe PubMed Central

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2 November 2019

278

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31 January 2017

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2 November 2019

27

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31 January 2017

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2 November 2019

24776-24790

1 reference

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2 November 2019

Binding of ligands and activation of transcription by nuclear receptors.

1 reference

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21 January 2018

Nuclear receptors and lipid physiology: opening the X-files

1 reference

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21 January 2018

The orphan receptors NGFI-B and steroidogenic factor 1 establish monomer binding as a third paradigm of nuclear receptor-DNA interaction

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21 January 2018

Identification of the DNA binding site for NGFI-B by genetic selection in yeast

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21 January 2018

Unique response pathways are established by allosteric interactions among nuclear hormone receptors

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21 January 2018

A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1

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21 January 2018

A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily

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21 January 2018

Activation of the inducible orphan receptor gene nur77 by serum growth factors: dissociation of immediate-early and delayed-early responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Nur77 is differentially modified in PC12 cells upon membrane depolarization and growth factor treatment

1 reference

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21 January 2018

A human early response gene homologous to murine nur77 and rat NGFI-B, and related to the nuclear receptor superfamily

1 reference

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21 January 2018

Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Regulation of the Nur77 orphan steroid receptor in activation-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Nigrostriatal innervation is preserved in Nurr1-null mice, although dopaminergic neuron precursors are arrested from terminal differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Characterization of the 5'-flanking region of the human dopamine transporter gene

1 reference

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21 January 2018

4.5 kb of the rat tyrosine hydroxylase 5' flanking sequence directs tissue specific expression during development and contains consensus sites for multiple transcription factors

1 reference

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21 January 2018

Mutation analysis of the retinoid X receptor beta, nuclear-related receptor 1, and peroxisome proliferator-activated receptor alpha genes in schizophrenia and alcohol dependence: possible haplotype association of nuclear-related receptor 1 gene to a

1 reference

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21 January 2018

Mutation analysis of the human NR4A2 gene, an essential gene for midbrain dopaminergic neurogenesis, in schizophrenic patients

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Involvement of the nuclear orphan receptor NURR1 in the regulation of corticotropin-releasing hormone expression and actions in human inflammatory arthritis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Vitamin A and apoptosis in prostate cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Dual roles of Nur77 in selective regulation of apoptosis and cell cycle by TPA and ATRA in gastric cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Induction of apoptosis by TPA and VP-16 is through translocation of TR3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Transcriptional induction of Nur77 by indomethacin that results in apoptosis of colon cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Early induction of the orphan nuclear receptor NOR-1 during cell death of the human breast cancer cell line MCF-7.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines.

1 reference

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21 January 2018

Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Nuclear receptors Nor1 and NGFI-B/Nur77 play similar, albeit distinct, roles in the hypothalamo-pituitary-adrenal axis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Endocrine and neurogenic regulation of the orphan nuclear receptors Nur77 and Nurr-1 in the adrenal glands

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

The orphan nuclear receptor NGFI-B regulates expression of the gene encoding steroid 21-hydroxylase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Activation of nuclear orphan receptor NURR1 transcription by NF-kappa B and cyclic adenosine 5'-monophosphate response element-binding protein in rheumatoid arthritis synovial tissue

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Molecular basis of mature T-cell leukemia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Nuclear hormone receptors in T lymphocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

The AF2 domain of the orphan nuclear receptor TEC is essential for the transcriptional activity of the oncogenic fusion protein EWS/TEC.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Atherosclerosis — An Inflammatory Disease

1 reference

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21 January 2018

Inflammatory bio-markers and cardiovascular risk prediction

1 reference

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21 January 2018

Heterodimerization between members of the Nur subfamily of orphan nuclear receptors as a novel mechanism for gene activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

The coactivator-associated arginine methyltransferase is necessary for muscle differentiation: CARM1 coactivates myocyte enhancer factor-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

A dynamic role for HDAC7 in MEF2-mediated muscle differentiation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Identification and characterization of a novel corepressor interaction region in RVR and Rev-erbA alpha

1 reference

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21 January 2018

Characterization of the AB (AF-1) region in the muscle-specific retinoid X receptor-gamma: evidence that the AF-1 region functions in a cell-specific manner

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

An amino-terminal c-myc domain required for neoplastic transformation activates transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

1 reference

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21 January 2018

Transcription activation by the adenovirus E1a protein

1 reference

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21 January 2018

Protein docking using spherical polar Fourier correlations.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Structure, mapping and expression of a human NOR-1 gene, the third member of the Nur77/NGFI-B family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Alternative splicing generates isoforms of human neuron-derived orphan receptor-1 (NOR-1) mRNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor and cell-specific.

1 reference

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21 January 2018

The activation function-1 domain of Nur77/NR4A1 mediates trans-activation, cell specificity, and coactivator recruitment

1 reference

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21 January 2018

X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation.

1 reference

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21 January 2018

Synergy between estrogen receptor alpha activation functions AF1 and AF2 mediated by transcription intermediary factor TIF2.

1 reference

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21 January 2018

Nuclear receptor and apoptosis initiator NGFI-B is a substrate for kinase ERK2.

1 reference

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21 January 2018

Activity of the Nurr1 Carboxyl-terminal Domain Depends on Cell Type and Integrity of the Activation Function 2

1 reference

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21 January 2018

Single-agent therapy with oral mercaptopurine for nonlymphoid blast crisis of chronic myeloid leukemia.

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21 January 2018

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21 January 2018

The interaction of 6-mercaptopurine (6-MP) and methotrexate (MTX).

1 reference

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21 January 2018

Activation and induction of NUR77/NURR1 in corticotrophs by CRH/cAMP: involvement of calcium, protein kinase A, and MAPK pathways

1 reference

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21 January 2018

Differential regulation of primary response gene expression in skeletal muscle cells through multiple signal transduction pathways

1 reference

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21 January 2018

Akt phosphorylates and regulates the orphan nuclear receptor Nur77

1 reference

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21 January 2018

Akt inhibits the orphan nuclear receptor Nur77 and T-cell apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

Transcriptional regulation of nuclear orphan receptor, NOR-1, by Ca(2+)/calmodulin-dependent protein kinase cascade.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300088200

21 January 2018

p300 Mediates Functional Synergism between AF-1 and AF-2 of Estrogen Receptor α and β by Interacting Directly with the N-terminal A/B Domains

1 reference

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21 January 2018

Induction of Mitogen-Inducible Nuclear Orphan Receptor by Interleukin 1 in Human Synovial and Gingival Fibroblasts

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21 January 2018

Identifiers

10.1074/JBC.M300088200

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709428%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709428%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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