(Q21985890)

Leucine-rich repeat domain superfamily

1 reference

stated in

NACHT nucleoside triphosphatase family

1 reference

based on heuristic

inferred from protein domain or family

Leucine-rich repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

1 reference

14 February 2019

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

phosphatidylinositol 3-kinase regulatory subunit binding

IEA

1 reference

14 February 2019

NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

3 references

16 July 2018

CATERPILLER 16.2 (CLR16.2), a novel NBD/LRR family member that negatively regulates T cell function

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5DU56&geneProductId=UniProtKB:Q5DU56

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5DU56&geneProductId=UniProtKB:Q5DU56

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5DU56&geneProductId=UniProtKB:Q5DU56

microtubule organizing center

IEA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5DU56&geneProductId=UniProtKB:Q5DU56

perinuclear region of cytoplasm

ISO

2 references

4 references

14 February 2019

CATERPILLER 16.2 (CLR16.2), a novel NBD/LRR family member that negatively regulates T cell function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

negative regulation of interleukin-6 production

IBA

biological process

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

14 February 2019

NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

14 February 2019

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

regulation of protein ubiquitination

2 references

14 February 2019

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

14 February 2019

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

negative regulation of interleukin-1 beta production

IDA

1 reference

14 February 2019

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

response to lipopolysaccharide

1 reference

14 February 2019

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

1 reference

14 February 2019

CATERPILLER 16.2 (CLR16.2), a novel NBD/LRR family member that negatively regulates T cell function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

negative regulation of I-kappaB kinase/NF-kappaB signaling

ISS

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5DU56&geneProductId=UniProtKB:Q5DU56

16 July 2018

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5DU56&geneProductId=UniProtKB:Q5DU56

16 July 2018

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5DU56&geneProductId=UniProtKB:Q5DU56

negative regulation of interleukin-12 production

IGI

1 reference

14 February 2019

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

negative regulation of phosphatidylinositol 3-kinase signaling

1 reference

14 February 2019

NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

negative regulation of interferon-alpha production

1 reference

14 February 2019

NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

negative regulation of interferon-beta production

1 reference

14 February 2019

NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

negative regulation of innate immune response

1 reference

14 February 2019

NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

negative regulation of fibroblast proliferation

1 reference

14 February 2019

NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

negative regulation of epithelial cell proliferation

1 reference

14 February 2019

NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

negative regulation of cytokine production involved in inflammatory response

1 reference

14 February 2019

NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

negative regulation of inflammatory response

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

14 February 2019

NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

intracellular signal transduction

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

negative regulation of I-kappaB kinase/NF-kappaB signaling

IBA

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

14 February 2019

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

14 February 2019

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DU56

1 reference

NACHT nucleoside triphosphatase domain

1 reference

stated in