(Q28975611)

18 October 2017

NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer (English)

1 reference

NLR family, CARD domain containing 3

18 October 2017

1 reference

GOA release 2020-03-11

author

Philip Rosenstiel

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27951586%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Rksubbarao Malireddi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27951586%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Bhesh Raj Sharma

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27951586%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Rajendra Karki

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27951586%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Si Ming Man

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27951586%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Sannula Kesavardhana

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27951586%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Qifan Zhu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27951586%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Xiaopeng Qi

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27951586%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Stephane Pelletier

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27951586%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Peter Vogel

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27951586%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Amanda R Burton

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27951586%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Thirumala-Devi Kanneganti

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27951586%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

language of work or name

English

0 references

publication date

12 December 2016

1 reference

18 October 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27951586%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

540

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27951586%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

issue

7634

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27951586%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

583-587

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27951586%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

7 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5468516/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Converging roles of caspases in inflammasome activation, cell death and innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

Expression profile of innate immune receptors, NLRs and AIM2, in human colorectal cancer: correlation with cancer stages and inflammasome components

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

Mouse genome engineering via CRISPR-Cas9 for study of immune function

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

Cutting edge: STING mediates protection against colorectal tumorigenesis by governing the magnitude of intestinal inflammation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

eIF4F is a nexus of resistance to anti-BRAF and anti-MEK cancer therapies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

Making new contacts: the mTOR network in metabolism and signalling crosstalk

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

An anti-inflammatory NOD-like receptor is required for microglia development

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

NLRs at the intersection of cell death and immunity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

CATERPILLER 16.2 (CLR16.2), a novel NBD/LRR family member that negatively regulates T cell function

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

Differential roles of Toll-like receptors in the elicitation of proinflammatory responses by macrophages.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5468516

The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis.

3 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20597

Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20597

Lipopolysaccharide activates Akt in human alveolar macrophages resulting in nuclear accumulation and transcriptional activity of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20597

Diagnosis and nonsurgical management of osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20597

Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated cytokine expression in mouse macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20597

Molecular signatures of a disturbed nasal barrier function in the primary tissue of Wegener's granulomatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20597

21 January 2018

Identifiers

DOI

10.1038/NATURE20597

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27951586%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27951586%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

27951586

1 reference