(Q28505592)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling (English)

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

0 references

0 references

NLR family, pyrin domain containing 12

1 reference

TNF receptor-associated factor 3

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Janelle C Arthur

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

author name string

Monika Schneider

3

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Christian Jobin

11

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Irving C Allen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Justin E Wilson

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

John D Lich

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Reid A Roberts

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Rita-Marie T Woodford

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Beckley K Davis

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Joshua M Uronis

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Hans H Herfarth

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Arlin B Rogers

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Jenny P-Y Ting

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

language of work or name

English

0 references

publication date

12 April 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

volume

36

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

issue

5

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

page(s)

742-754

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

28 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3658309/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasome

19 March 2017

1 reference

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19 March 2017

1 reference

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Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

A role for the human nucleotide-binding domain, leucine-rich repeat-containing family member NLRC5 in antiviral responses

19 March 2017

1 reference

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Mutations in NALP12 cause hereditary periodic fever syndromes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

ATP binding by monarch-1/NLRP12 is critical for its inhibitory function

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

19 March 2017

1 reference

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Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis

7 April 2017

1 reference

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The role of myeloid cells in the promotion of tumour angiogenesis

7 April 2017

1 reference

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IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

Role of CXCL13-CXCR5 crosstalk between malignant neuroblastoma cells and Schwannian stromal cells in neuroblastic tumors.

29 September 2017

1 reference

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Non-canonical NF-κB signaling pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

Classical NF-kappaB activation negatively regulates noncanonical NF-kappaB-dependent CXCL12 expression

29 September 2017

1 reference

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IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation

29 September 2017

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29 September 2017

1 reference

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MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18

29 September 2017

1 reference

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Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

IKKalpha and IKKbeta each function to regulate NF-kappaB activation in the TNF-induced/canonical pathway

29 September 2017

1 reference

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29 September 2017

1 reference

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Constitutive non-canonical NFkappaB signaling in pancreatic cancer cells

29 September 2017

1 reference

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The innate immune receptor Nod1 protects the intestine from inflammation-induced tumorigenesis

29 September 2017

1 reference

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29 September 2017

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DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

29 September 2017

1 reference

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Control of canonical NF-kappaB activation through the NIK-IKK complex pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

NLRX1 is a regulator of mitochondrial antiviral immunity

29 September 2017

1 reference

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29 September 2017

1 reference

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NOD2 transgenic mice exhibit enhanced MDP-mediated down-regulation of TLR2 responses and resistance to colitis induction

29 September 2017

1 reference

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29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

IL-1 beta -converting enzyme (caspase-1) in intestinal inflammation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

Control of Intestinal Homeostasis, Colitis, and Colitis-Associated Colorectal Cancer by the Inflammatory Caspases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

Nod1/RICK and TLR signaling regulate chemokine and antimicrobial innate immune responses in mesothelial cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3658309

Flat Colorectal Cancers Are Genetically Determined and Progress to Invasion without Going through a Polypoid Stage

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22503542

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Adenoviral gene transfer of stromal cell-derived factor-1 to murine tumors induces the accumulation of dendritic cells and suppresses tumor growth

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22503542

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.IMMUNI.2012.03.012

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22503542%20AND%20SRC:MED&resulttype=core&format=json