(Q21986156)

English

NLR family, pyrin domain containing 12

mammalian protein found in Mus musculus

monarch-1
PYPAF7
NACHT, LRR and PYD domains-containing protein 12
PYRIN-containing APAF1-like protein 7
Nlrp12
NACHT, LRR and PYD containing protein 12

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Statements

1 reference

25 May 2022

1 reference

19 January 2017

Death-like domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/E9Q5R7

P-loop containing nucleoside triphosphate hydrolase

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/E9Q5R7

Leucine-rich repeat domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/E9Q5R7

NACHT-associated domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

NACHT nucleoside triphosphatase family

1 reference

based on heuristic

inferred from protein domain or family

DAPIN domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Leucine-rich repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q5R7

1 reference

14 February 2019

NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q5R7

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q5R7

3 references

1 reference

14 February 2019

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q5R7

determination method

ISO

biological process

cellular response to cytokine stimulus

1 reference

27 March 2018

Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=E9Q5R7&geneProductId=UniProtKB:E9Q5R7

determination method

IMP

dendritic cell migration

1 reference

14 February 2019

Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q5R7

determination method

IMP

negative regulation of NIK/NF-kappaB signaling

1 reference

14 February 2019

NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q5R7

determination method

IMP

negative regulation of ERK1 and ERK2 cascade

1 reference

14 February 2019

NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E9Q5R7

determination method

IMP

negative regulation of I-kappaB kinase/NF-kappaB signaling

3 references

regulation of cysteine-type endopeptidase activity involved in apoptotic process

3 references

positive regulation of MHC class I biosynthetic process

3 references

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

(Q21986156)

NLR family, pyrin domain containing 12

Statements

Identifiers

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