(Q38969978)

8 September 2017

eIF4F is a nexus of resistance to anti-BRAF and anti-MEK cancer therapies (English)

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8 September 2017

15

Alexander M Eggermont

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Caroline Robert

17

object named as

Caroline Robert

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author name string

Lise Boussemart

1

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8 September 2017

Hélène Malka-Mahieu

2

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8 September 2017

Isabelle Girault

3

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8 September 2017

Delphine Allard

4

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8 September 2017

Oskar Hemmingsson

5

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8 September 2017

Gorana Tomasic

6

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8 September 2017

Marina Thomas

7

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8 September 2017

Christine Basmadjian

8

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8 September 2017

Nigel Ribeiro

9

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8 September 2017

Frédéric Thuaud

10

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8 September 2017

Christina Mateus

11

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8 September 2017

Emilie Routier

12

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8 September 2017

Nyam Kamsu-Kom

13

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8 September 2017

Sandrine Agoussi

14

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8 September 2017

Alexander M Eggermont

15

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8 September 2017

Laurent Désaubry

16

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8 September 2017

Stéphan Vagner

18

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8 September 2017

language of work or name

English

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publication date

27 July 2014

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8 September 2017

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8 September 2017

513

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8 September 2017

7516

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8 September 2017

105-109

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https://scigraph.springernature.com/pub.10.1038/nature13572

8 September 2017

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cites work

Identification of direct transcriptional targets of (V600E)BRAF/MEK signalling in melanoma

1 reference

12 December 2020

Synthetic analogue of rocaglaol displays a potent and selective cytotoxicity in cancer cells: involvement of apoptosis inducing factor and caspase-12.

1 reference

12 December 2020

Resistance to the translation initiation inhibitor silvestrol is mediated by ABCB1/P-glycoprotein overexpression in acute lymphoblastic leukemia cells

1 reference

12 December 2020

Tumor adaptation and resistance to RAF inhibitors

1 reference

12 December 2020

Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF-mutant thyroid carcinomas.

1 reference

12 December 2020

Evidence for a functionally relevant rocaglamide binding site on the eIF4A-RNA complex

1 reference

12 December 2020

The biological and therapeutic relevance of mRNA translation in cancer

1 reference

12 December 2020

The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments

1 reference

12 December 2020

BH3-only protein silencing contributes to acquired resistance to PLX4720 in human melanoma

1 reference

12 December 2020

Challenging resistance mechanisms to therapies for metastatic melanoma.

1 reference

12 December 2020

Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors

1 reference

12 December 2020

Selective BRAFV600E inhibitor PLX4720, requires TRAIL assistance to overcome oncogenic PIK3CA resistance

1 reference

12 December 2020

(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway

1 reference

12 December 2020

Translational control in cancer.

1 reference

12 December 2020

A unifying model for mTORC1-mediated regulation of mRNA translation.

1 reference

12 December 2020

Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G

1 reference

12 December 2020

Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy

1 reference

12 December 2020

Synergistic effect of inhibiting translation initiation in combination with cytotoxic agents in acute myelogenous leukemia cells

1 reference

12 December 2020

Inhibitors of translation targeting eukaryotic translation initiation factor 4A.

1 reference

12 December 2020

Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.

1 reference

12 December 2020

Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model

1 reference

12 December 2020

Identifiers

DOI

10.1038/NATURE13572

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Dimensions Publication ID

8 September 2017

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1 reference