(Q21986047)

Protein kinase-like domain superfamily

1 reference

Death-like domain superfamily

1 reference

Death domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

protein serine/threonine kinase activity

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

27 March 2018

Identification and characterization of murine IRAK-M

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

Identification and characterization of murine IRAK-M

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

protein serine/threonine kinase activity

magnesium ion binding

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

Identification and characterization of murine IRAK-M

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

27 March 2018

Differential regulation and role of interleukin-1 receptor associated kinase-M in innate immunity signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

27 March 2018

Differential regulation and role of interleukin-1 receptor associated kinase-M in innate immunity signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

Differential regulation and role of interleukin-1 receptor associated kinase-M in innate immunity signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

Differential regulation and role of interleukin-1 receptor associated kinase-M in innate immunity signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

regulation of apoptotic process

biological process

1 reference

1 January 2018

Comparative analysis of apoptosis and inflammation genes of mice and humans

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

positive regulation of macrophage tolerance induction

RCA

1 reference

14 February 2019

IRAK-M is a negative regulator of Toll-like receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

negative regulation of protein catabolic process

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

Differential regulation and role of interleukin-1 receptor associated kinase-M in innate immunity signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

response to exogenous dsRNA

1 reference

14 February 2019

IRAK-M is a negative regulator of Toll-like receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

cytokine-mediated signaling pathway

1 reference

27 March 2018

Identification and characterization of murine IRAK-M

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

negative regulation of interleukin-6 production

1 reference

14 February 2019

IRAK-M is a negative regulator of Toll-like receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

negative regulation of cytokine-mediated signaling pathway

IC

1 reference

14 February 2019

IRAK-M is a negative regulator of Toll-like receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

regulation of protein-containing complex disassembly

IC

1 reference

14 February 2019

Identification and characterization of murine IRAK-M

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

interleukin-1-mediated signaling pathway

3 references

protein phosphorylation

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

Identification and characterization of murine IRAK-M

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

response to lipopolysaccharide

1 reference

14 February 2019

IRAK-M is a negative regulator of Toll-like receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

positive regulation of NF-kappaB transcription factor activity

3 references

negative regulation of MAP kinase activity

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

27 March 2018

Differential regulation and role of interleukin-1 receptor associated kinase-M in innate immunity signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

response to peptidoglycan

1 reference

14 February 2019

IRAK-M is a negative regulator of Toll-like receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

protein autophosphorylation

1 reference

14 February 2019

Identification and characterization of murine IRAK-M

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

negative regulation of macrophage cytokine production

1 reference

14 February 2019

IRAK-M is a negative regulator of Toll-like receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

negative regulation of tumor necrosis factor production

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

10 September 2018

IRAK-M is a negative regulator of Toll-like receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

negative regulation of interleukin-12 production

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

10 September 2018

IRAK-M is a negative regulator of Toll-like receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

1 reference

1 January 2018

Comparative analysis of apoptosis and inflammation genes of mice and humans

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K4B2&geneProductId=UniProtKB:Q8K4B2

MyD88-dependent toll-like receptor signaling pathway

RCA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

intracellular signal transduction

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

negative regulation of MAP kinase activity

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

Differential regulation and role of interleukin-1 receptor associated kinase-M in innate immunity signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

positive regulation of NF-kappaB transcription factor activity

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

Identification and characterization of murine IRAK-M

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

interleukin-1-mediated signaling pathway

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

Identification and characterization of murine IRAK-M

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

negative regulation of interleukin-12 production

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

IRAK-M is a negative regulator of Toll-like receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

negative regulation of tumor necrosis factor production

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

IRAK-M is a negative regulator of Toll-like receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K4B2

1 reference

protein kinase domain

1 reference