(Q21986509)

http://www.ebi.ac.uk/interpro/protein/O70582

PLAT/LH2 domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O70582

Lipoxygenase, mammalian

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O70582

Lipoxygenase, C-terminal domain, protein family

1 reference

Lipoxygenase, iron binding site, protein family

1 reference

PLAT/LH2 domain, protein family

1 reference

Lipoxygenase, conserved site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

8 April 2019

arachidonate 12(S)-lipoxygenase activity

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

8 April 2019

Sequence determinants for the reaction specificity of murine (12R)-lipoxygenase: targeted substrate modification and site-directed mutagenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

8 April 2019

Murine 12(R)-lipoxygenase: functional expression, genomic structure and chromosomal localization

GOA

curator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

1 reference

8 April 2019

cDNA cloning, genomic structure, and chromosomal localization of a novel murine epidermis-type lipoxygenase

GOA

curator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

oxidoreductase activity

1 reference

8 April 2019

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

linoleate 9S-lipoxygenase activity

ISO

1 reference

8 April 2019

Sequence determinants for the reaction specificity of murine (12R)-lipoxygenase: targeted substrate modification and site-directed mutagenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

arachidonate 12(S)-lipoxygenase activity

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

14 February 2019

Sequence determinants for the reaction specificity of murine (12R)-lipoxygenase: targeted substrate modification and site-directed mutagenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

14 February 2019

Murine 12(R)-lipoxygenase: functional expression, genomic structure and chromosomal localization

GOA

curator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

linoleic acid metabolic process

biological process

1 reference

8 April 2019

Sequence determinants for the reaction specificity of murine (12R)-lipoxygenase: targeted substrate modification and site-directed mutagenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

establishment of skin barrier

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

ceramide biosynthetic process

1 reference

8 April 2019

12R-lipoxygenase deficiency disrupts epidermal barrier function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

fatty acid metabolic process

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

positive regulation of gene expression

bicellular tight junction assembly

1 reference

8 April 2019

12R-lipoxygenase deficiency disrupts epidermal barrier function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

1 reference

8 April 2019

Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

positive regulation of mucus secretion

IMP

arachidonic acid metabolic process

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

8 April 2019

Sequence determinants for the reaction specificity of murine (12R)-lipoxygenase: targeted substrate modification and site-directed mutagenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

sphingolipid metabolic process

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70582