(Q28585387)

31 January 2017

title

12R-lipoxygenase deficiency disrupts epidermal barrier function (English)

1 reference

Arachidonate 12-lipoxygenase, 12R type

31 January 2017

main subject

1 reference

GOA release 2020-03-11

Gerhard Liebisch

8

0 references

Gerd Schmitz

object named as

Gerd Schmitz

9

0 references

Peter Krieg

10

object named as

Peter Krieg

1 reference

31 January 2017

Nikolas Epp

1

1 reference

31 January 2017

Gerhard Fürstenberger

2

1 reference

31 January 2017

Karsten Müller

3

1 reference

31 January 2017

Silvia de Juanes

4

1 reference

31 January 2017

Michael Leitges

5

1 reference

31 January 2017

Ingrid Hausser

6

1 reference

31 January 2017

Florian Thieme

7

1 reference

31 January 2017

language of work or name

English

0 references

publication date

9 April 2007

1 reference

31 January 2017

published in

Journal of Cell Biology

1 reference

31 January 2017

volume

177

1 reference

31 January 2017

issue

1

1 reference

31 January 2017

page(s)

173–182

1 reference

Human and mouse eLOX3 have distinct substrate specificities: implications for their linkage with lipoxygenases in skin

31 January 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

The epidermal barrier function is dependent on the serine protease CAP1/Prss8

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Mutations associated with a congenital form of ichthyosis (NCIE) inactivate the epidermal lipoxygenases 12R-LOX and eLOX3

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

The membrane organization of leukotriene synthesis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

The lipoxygenase gene ALOXE3 implicated in skin differentiation encodes a hydroperoxide isomerase

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Barrier function of the skin: "la raison d'être" of the epidermis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Mice with targeted disruption of the fatty acid transport protein 4 (Fatp 4, Slc27a4) gene show features of lethal restrictive dermopathy

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Enzymic characterization of epidermis-derived 12-lipoxygenase isoenzymes

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Lessons from loricrin-deficient mice: compensatory mechanisms maintaining skin barrier function in the absence of a major cornified envelope protein

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Klf4 is a transcription factor required for establishing the barrier function of the skin

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

cDNA cloning, genomic structure, and chromosomal localization of a novel murine epidermis-type lipoxygenase

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Murine 12(R)-lipoxygenase: functional expression, genomic structure and chromosomal localization

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

A 12R-lipoxygenase in human skin: mechanistic evidence, molecular cloning, and expression

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Mutations in a new cytochrome P450 gene in lamellar ichthyosis type 3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Mutation spectrum and functional analysis of epidermis-type lipoxygenases in patients with autosomal recessive congenital ichthyosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Stratum corneum defensive functions: an integrated view

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Functions of peroxisome proliferator-activated receptors (PPAR) in skin homeostasis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Molecular genetics of the ichthyoses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Complex redundancy to build a simple epidermal permeability barrier

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Loss of proteolytically processed filaggrin caused by epidermal deletion of Matriptase/MT-SP1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Lipoxygenase-3 (ALOXE3) and 12(R)-lipoxygenase (ALOX12B) are mutated in non-bullous congenital ichthyosiform erythroderma (NCIE) linked to chromosome 17p13.1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

A gene cluster encoding human epidermis-type lipoxygenases at chromosome 17p13.1: cloning, physical mapping, and expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Sphingolipid activator proteins are required for epidermal permeability barrier formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Human 12(R)-lipoxygenase and the mouse ortholog. Molecular cloning, expression, and gene chromosomal assignment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Identification of two intermediates during processing of profilaggrin to filaggrin in neonatal mouse epidermis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Improved procedure for the separation of major stratum corneum lipids by means of automated multiple development thin-layer chromatography

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene

3 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200612116

Sphingolipid metabolism during epidermal barrier development in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200612116

The epidermal permeability barrier: from the early days at Harvard to emerging concepts

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200612116

Matriptase/MT-SP1 is required for postnatal survival, epidermal barrier function, hair follicle development, and thymic homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200612116

Deficiency of epidermal protein-bound omega-hydroxyceramides in atopic dermatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200612116

Basis for improved permeability barrier homeostasis induced by PPAR and LXR activators: liposensors stimulate lipid synthesis, lamellar body secretion, and post-secretory lipid processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200612116

Stratum corneum moisturization at the molecular level.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200612116

Epidermis-type lipoxygenases.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Patterned acquisition of skin barrier function during development.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064121

Prevalent and Rare Mutations in the Gene Encoding Filaggrin Cause Ichthyosis Vulgaris and Predispose Individuals to Atopic Dermatitis

27 November 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200612116

Ceramide composition of the psoriatic scale

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200612116

Relationship between covalently bound ceramides and transepidermal water loss (TEWL)

21 January 2018

1 reference

12 December 2020

6-Hydroxy-4-sphingenine in human epidermal ceramides

1 reference

12 December 2020

The barrier function of skin: how to keep a tight lid on water loss

1 reference

12 December 2020

Diversity of mouse lipoxygenases: identification of a subfamily of epidermal isozymes exhibiting a differentiation-dependent mRNA expression pattern

1 reference

12 December 2020

Origin of the corneocyte lipid envelope (CLE): observations in harlequin ichthyosis and cultured human keratinocytes

1 reference

12 December 2020

Loss of normal profilaggrin and filaggrin in flaky tail (ft/ft) mice: an animal model for the filaggrin-deficient skin disease ichthyosis vulgaris

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200612116

1 reference

1 reference

1 reference

1 reference