Wikidata

(Q21986568)

English

Myosin, heavy polypeptide 6, cardiac muscle, alpha

mammalian protein found in Mus musculus

  • myosin heavy chain 6
  • myHC-alpha
  • cardiac myosin heavy chain alpha isoform
  • Myosin heavy chain, cardiac muscle alpha isoform
  • Myh6
  • myosin heavy chain, cardiac muscle, adult
  • myosin-6
  • alpha cardiac MHC
  • alpha myosin
  • cardiomyopathy, hypertrophic 1
  • Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha)
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No label defined

No description defined

Statements

molecular function
cell component
biological process
regulation of heart contraction
determination method or standard
IMP
7 references
retrieved
14 February 2019
stated in
Altered crossbridge kinetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
Electrophysiological abnormalities and arrhythmias in alpha MHC mutant familial hypertrophic cardiomyopathy mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
Altered cardiac excitation-contraction coupling in mutant mice with familial hypertrophic cardiomyopathy
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
Ablation of the murine alpha myosin heavy chain gene leads to dosage effects and functional deficits in the heart
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
A mouse model of familial hypertrophic cardiomyopathy
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
QT dispersion in alpha-myosin heavy-chain familial hypertrophic cardiomyopathy mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the alpha cardiac myosin heavy chain gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
striated muscle contraction
determination method or standard
IEA
IMP
ISO
11 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
ISO
retrieved
14 February 2019
stated in
Altered crossbridge kinetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
Diastolic dysfunction and altered energetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function.
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
Electrophysiological abnormalities and arrhythmias in alpha MHC mutant familial hypertrophic cardiomyopathy mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
Altered cardiac excitation-contraction coupling in mutant mice with familial hypertrophic cardiomyopathy
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
Ablation of the murine alpha myosin heavy chain gene leads to dosage effects and functional deficits in the heart
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
A mouse model of familial hypertrophic cardiomyopathy
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the alpha cardiac myosin heavy chain gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
Differential cross-bridge kinetics of FHC myosin mutations R403Q and R453C in heterozygous mouse myocardium
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IEA
adult heart development
determination method or standard
IEA
IMP
ISO
7 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
ISO
retrieved
14 February 2019
stated in
Altered crossbridge kinetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function.
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
Ablation of the murine alpha myosin heavy chain gene leads to dosage effects and functional deficits in the heart
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the alpha cardiac myosin heavy chain gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
Differential cross-bridge kinetics of FHC myosin mutations R403Q and R453C in heterozygous mouse myocardium
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IMP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02566
determination method or standard
IEA

Identifiers

 
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