(Q21989670)

DNA topoisomerase, type IIA-like domain superfamily

1 reference

DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta

1 reference

Ribosomal protein S5 domain 2-type fold

1 reference

DNA topoisomerase, type IIA, subunit B, C-terminal

1 reference

Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily

1 reference

DNA topoisomerase II, eukaryotic-type

1 reference

Ribosomal protein S5 domain 2-type fold, subgroup

1 reference

C-terminal associated domain of TOPRIM, protein family

1 reference

DNA topoisomerase, type IIA, subunit B, domain 2, protein family

1 reference

DNA topoisomerase 2, TOPRIM domain, protein family

1 reference

DNA topoisomerase, type IIA, subunit A/C-terminal domain, protein family

1 reference

DTHCT, protein family

1 reference

Histidine kinase/HSP90-like ATPase family

1 reference

TOPRIM domain, protein family

1 reference

DNA topoisomerase, type IIA, conserved site, protein family

1 reference

DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity

1 reference

25 May 2022

1 reference

25 May 2022

9 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

Mutant isolation of mouse DNA topoisomerase II alpha in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

Analysis of expression and function of topoisomerase I and II during meiosis in male mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

Modulation of topoisomerase activities by tumor necrosis factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

3 references

magnesium ion binding

3 references

1 reference

14 February 2019

BAF complexes facilitate decatenation of DNA by topoisomerase IIα

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity

IPI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

DNA topoisomerase activity

2 references

3 references

sequence-specific DNA binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

6 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01320&geneProductId=UniProtKB:Q01320

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01320&geneProductId=UniProtKB:Q01320

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01320&geneProductId=UniProtKB:Q01320

21 June 2018

Condensin confers the longitudinal rigidity of chromosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01320&geneProductId=UniProtKB:Q01320

21 June 2018

Cellular distribution of mammalian DNA topoisomerase II is determined by its catalytically dispensable C-terminal domain

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01320&geneProductId=UniProtKB:Q01320

21 June 2018

Analysis of expression and function of topoisomerase I and II during meiosis in male mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01320&geneProductId=UniProtKB:Q01320

ribonucleoprotein complex

3 references

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

Cellular distribution of mammalian DNA topoisomerase II is determined by its catalytically dispensable C-terminal domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

Analysis of expression and function of topoisomerase I and II during meiosis in male mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

Condensin confers the longitudinal rigidity of chromosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

viral integration complex

IBA

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01320&geneProductId=UniProtKB:Q01320

resolution of meiotic recombination intermediates

biological process

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

1 reference

14 February 2019

DNA topoisomerase II is essential for preimplantation mouse development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

chromosome segregation

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

DNA topoisomerase II is essential for preimplantation mouse development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

Modulation of topoisomerase activities by tumor necrosis factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

IDA

DNA metabolic process

1 reference

14 February 2019

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

DNA topoisomerase II is essential for preimplantation mouse development

chromosome condensation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

regulation of circadian rhythm

1 reference

14 February 2019

Shikonin shortens the circadian period: possible involvement of Top2 inhibition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

hematopoietic progenitor cell differentiation

1 reference

14 February 2019

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

mitotic DNA integrity checkpoint signaling

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

sister chromatid segregation

IBA

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

IBA

DNA topological change

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

Cellular distribution of mammalian DNA topoisomerase II is determined by its catalytically dispensable C-terminal domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

14 February 2019

Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

positive regulation of transcription by RNA polymerase II

IDA

1 reference

14 February 2019

Possible role of DNA topoisomerase II on transcription of the homeobox gene Hox-2.1 in F9 embryonal carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

apoptotic chromosome condensation

3 references

negative regulation of DNA duplex unwinding

3 references

female meiotic nuclear division

1 reference

14 February 2019

Condensin confers the longitudinal rigidity of chromosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

female meiosis chromosome separation

1 reference

14 February 2019

Condensin confers the longitudinal rigidity of chromosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320

positive regulation of viral genome replication

TAS

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01320&geneProductId=UniProtKB:Q01320

physically interacts with

ISO

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

6843

language of work or name

English

retrieved

17 August 2016

has part(s)

DNA topoisomerase, type IIA, conserved site

1 reference

DNA topoisomerase, type IIA, subunit B, domain 2

1 reference

TOPRIM domain

1 reference

DTHCT

1 reference

DNA topoisomerase, type IIA, subunit A/C-terminal

1 reference

Histidine kinase/HSP90-like ATPase domain

1 reference

C-terminal associated domain of TOPRIM

1 reference

DNA topoisomerase 2, TOPRIM domain

1 reference