(Q21990150)

Sox 7/17/18, central domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

High mobility group box domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Sox, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

SOX18 directly interacts with MEF2C in endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

protein heterodimerization activity

IPI

1 reference

14 February 2019

Deciphering the Sox-Oct partner code by quantitative cooperativity measurements

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

sequence-specific DNA binding

1 reference

14 February 2019

Trans-activation and DNA-binding properties of the transcription factor, Sox-18

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

21 June 2018

Deciphering the Sox-Oct partner code by quantitative cooperativity measurements

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43680&geneProductId=UniProtKB:P43680

DNA-binding transcription factor activity

4 references

14 February 2019

Mouse mu opioid receptor distal promoter transcriptional regulation by SOX proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

The VCAM-1 gene that encodes the vascular cell adhesion molecule is a target of the Sry-related high mobility group box gene, Sox18

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

Trans-activation and DNA-binding properties of the transcription factor, Sox-18

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

DNA-binding transcription activator activity, RNA polymerase II-specific

4 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43680&geneProductId=UniProtKB:P43680

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43680&geneProductId=UniProtKB:P43680

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

6 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43680&geneProductId=UniProtKB:P43680

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43680&geneProductId=UniProtKB:P43680

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43680&geneProductId=UniProtKB:P43680

21 June 2018

SOX18 directly interacts with MEF2C in endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43680&geneProductId=UniProtKB:P43680

21 June 2018

Sox18 induces development of the lymphatic vasculature in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43680&geneProductId=UniProtKB:P43680

21 June 2018

Mouse mu opioid receptor distal promoter transcriptional regulation by SOX proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43680&geneProductId=UniProtKB:P43680

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

SOX18 directly interacts with MEF2C in endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

Sox18 induces development of the lymphatic vasculature in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

Mouse mu opioid receptor distal promoter transcriptional regulation by SOX proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

in utero embryonic development

IBA

biological process

4 references

14 February 2019

Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

Mice null for sox18 are viable and display a mild coat defect

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

Sox18 induces development of the lymphatic vasculature in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturation

IMP

vasculature development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

1 reference

14 February 2019

Contrasting effects of Sox17- and Sox18-sustained expression at the onset of blood specification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

positive regulation of transcription, DNA-templated

6 references

14 February 2019

SOX18 directly interacts with MEF2C in endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

The VCAM-1 gene that encodes the vascular cell adhesion molecule is a target of the Sry-related high mobility group box gene, Sox18

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

Cloning and functional analysis of the Sry-related HMG box gene, Sox18

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

Sox18 induces development of the lymphatic vasculature in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

Trans-activation and DNA-binding properties of the transcription factor, Sox-18

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

Redundant roles of Sox17 and Sox18 in early cardiovascular development of mouse embryos

endocardium formation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

blood vessel endothelial cell migration

IGI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

negative regulation of transcription, DNA-templated

IEA

1 reference

14 February 2019

Sox18 induces development of the lymphatic vasculature in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

endocardial cell differentiation

1 reference

14 February 2019

Redundant roles of Sox17 and Sox18 in early cardiovascular development of mouse embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

transcription, DNA-templated

IGI

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43680&geneProductId=UniProtKB:P43680

embryonic heart tube development

IEA

1 reference

14 February 2019

Redundant roles of Sox17 and Sox18 in early cardiovascular development of mouse embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

1 reference

21 June 2018

Non-muscle myosins 2A and 2B drive changes in cell morphology that occur as myoblasts align and fuse

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43680&geneProductId=UniProtKB:P43680

lymphatic endothelial cell differentiation

IGI

1 reference

14 February 2019

Sox18 induces development of the lymphatic vasculature in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

regulation of stem cell proliferation

IMP

1 reference

14 February 2019

Contrasting effects of Sox17- and Sox18-sustained expression at the onset of blood specification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

stem cell fate specification

1 reference

14 February 2019

Contrasting effects of Sox17- and Sox18-sustained expression at the onset of blood specification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43680&geneProductId=UniProtKB:P43680

21 June 2018

Sox18 induces development of the lymphatic vasculature in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43680&geneProductId=UniProtKB:P43680

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43680&geneProductId=UniProtKB:P43680

negative regulation of transcription by RNA polymerase II

IEA

3 references

3 references

14 February 2019

Redundant roles of Sox17 and Sox18 in postnatal angiogenesis in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

Sox18 induces development of the lymphatic vasculature in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43680

positive regulation of transcription by RNA polymerase II

IBA

3 references

1 reference

Sox 7/17/18, central domain

1 reference

stated in

High mobility group box domain

1 reference

stated in