Wikidata

(Q21990370)

English

Recombination signal binding protein for immunoglobulin kappa J region

mammalian protein found in Mus musculus

  • RBP-J kappa
  • Rbpj
  • J-kappa recombination signal binding protein
  • J kappa-recombination signal-binding protein
  • recombining binding protein suppressor of hairless
  • Jkappa recombination signal binding protein
In more languages

Statements

molecular function
protein binding
determination method
IPI
7 references
retrieved
14 February 2019
stated in
p48 subunit of mouse PTF1 binds to RBP-Jkappa/CBF-1, the intracellular mediator of Notch signalling, and is expressed in the neural tube of early stage embryos
GOA
curator
UniProt
UniProt protein ID
P31266
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IPI
retrieved
14 February 2019
stated in
RBP-L, a transcription factor related to RBP-Jkappa
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IPI
retrieved
14 February 2019
stated in
Structure and Function of the CSL-KyoT2 Corepressor Complex: A Negative Regulator of Notch Signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IPI
retrieved
14 February 2019
stated in
Notch1 regulates the fate of cardiac progenitor cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IPI
retrieved
14 February 2019
stated in
Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H)
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IPI
retrieved
14 February 2019
stated in
Pten coordinates retinal neurogenesis by regulating Notch signalling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IPI
retrieved
14 February 2019
stated in
Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IPI
DNA-binding transcription activator activity, RNA polymerase II-specific
determination method
IBA
IDA
IEA
ISO
6 references
retrieved
1 January 2018
stated in
Slug is a direct Notch target required for initiation of cardiac cushion cellularization
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
ISO
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IEA
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IEA
retrieved
1 January 2018
stated in
Notch signaling regulates left-right asymmetry determination by inducing Nodal expression
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IDA
retrieved
1 January 2018
stated in
Notch signaling is essential for ventricular chamber development
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IBA
cell component
nucleus
determination method
IC
IDA
IEA
ISO
ISS
9 references
retrieved
5 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P31266
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
ISS
retrieved
5 June 2018
stated in
HERP1 is a cell type-specific primary target of Notch
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
ISO
retrieved
5 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P31266
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IEA
retrieved
5 June 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IEA
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IEA
retrieved
5 June 2018
stated in
Canonical notch signaling functions as a commitment switch in the epidermal lineage
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IDA
retrieved
5 June 2018
stated in
Conservation of the Notch signalling pathway in mammalian neurogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IDA
retrieved
5 June 2018
stated in
Notch signaling is essential for ventricular chamber development
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IDA
retrieved
5 June 2018
stated in
RBP-L, a transcription factor related to RBP-Jkappa
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IC
nucleus
determination method
IBA
IC
IDA
IEA
ISO
ISS
10 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P31266
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
ISS
retrieved
14 February 2019
stated in
HERP1 is a cell type-specific primary target of Notch
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P31266
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IEA
retrieved
14 February 2019
stated in
Canonical notch signaling functions as a commitment switch in the epidermal lineage
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IDA
retrieved
14 February 2019
stated in
Conservation of the Notch signalling pathway in mammalian neurogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IDA
retrieved
14 February 2019
stated in
Notch signaling is essential for ventricular chamber development
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IDA
retrieved
14 February 2019
stated in
RBP-L, a transcription factor related to RBP-Jkappa
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IC
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IBA
biological process
positive regulation of transcription by RNA polymerase II
determination method
IDA
IEA
IMP
ISO
9 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
ISO
retrieved
14 February 2019
stated in
Monitoring Notch1 activity in development: evidence for a feedback regulatory loop
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IMP
retrieved
14 February 2019
stated in
Notch signaling is essential for ventricular chamber development
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IMP
retrieved
14 February 2019
stated in
Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation.
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IMP
retrieved
14 February 2019
stated in
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IMP
retrieved
14 February 2019
stated in
Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IMP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IEA
retrieved
14 February 2019
stated in
Notch signaling regulates left-right asymmetry determination by inducing Nodal expression
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IDA
retrieved
14 February 2019
stated in
RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genes
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IDA
Notch signaling pathway
determination method
IEA
IGI
IMP
ISO
8 references
retrieved
5 June 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
ISO
retrieved
5 June 2018
stated in
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IMP
retrieved
5 June 2018
stated in
RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IMP
retrieved
5 June 2018
stated in
Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IMP
retrieved
5 June 2018
stated in
Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IMP
retrieved
5 June 2018
stated in
RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IGI
retrieved
5 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P31266
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IEA
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266
determination method
IEA
negative regulation of transcription by RNA polymerase II
determination method
IBA
IEA
IMP
ISO
6 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
ISO
retrieved
14 February 2019
stated in
Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IMP
retrieved
14 February 2019
stated in
Notch signaling is essential for ventricular chamber development
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IMP
retrieved
14 February 2019
stated in
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IMP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IBA
Notch signaling pathway
determination method
IBA
IEA
IGI
IMP
ISO
9 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
ISO
retrieved
14 February 2019
stated in
Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IMP
retrieved
14 February 2019
stated in
RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IMP
retrieved
14 February 2019
stated in
Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IMP
retrieved
14 February 2019
stated in
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IMP
retrieved
14 February 2019
stated in
RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IGI
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P31266
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266
determination method
IBA

Identifiers

 
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