(Q22008672)

Journal of Biological Chemistry

GOA release 2020-03-11

S Hunter

1

S

Hunter

1 reference

7 February 2023

E A Burton

series ordinal

2

author given names

E A

author last names

Burton

1 reference

7 February 2023

S C Wu

series ordinal

3

author given names

S C

author last names

Wu

1 reference

7 February 2023

S M Anderson

series ordinal

4

author given names

S M

author last names

Anderson

1 reference

7 February 2023

language of work or name

English

0 references

publication date

22 January 1999

0 references

published in

0 references

volume

274

0 references

page(s)

2097-106

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issue

4

0 references

cites work

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

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Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras

21 January 2018

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Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

21 January 2018

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The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

B cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Interaction between the amino-terminal SH3 domain of CRK and its natural target proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Role of IRS-2 in insulin and cytokine signalling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Mutant of insulin receptor substrate-1 incapable of activating phosphatidylinositol 3-kinase did not mediate insulin-stimulated maturation of Xenopus laevis oocytes.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Phosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

p120cbl is a cytosolic adapter protein that associates with phosphoinositide 3-kinase in response to epidermal growth factor in PC12 and other cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Formation of c-Cbl.phosphatidylinositol 3-kinase complexes on lymphocyte membranes by a p56lck-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

21 January 2018

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The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Interactions of Cbl with Grb2 and phosphatidylinositol 3'-kinase in activated Jurkat cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Identification of the major tyrosine kinase substrate in signaling complexes formed after engagement of Fc gamma receptors

21 January 2018

1 reference

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Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Deficient tyrosine phosphorylation of c-Cbl and associated proteins in phorbol ester-resistant EL4 mouse thymoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

IgM antigen receptor complex contains phosphoprotein products of B29 and mb-1 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Myc and Max proteins possess distinct transcriptional activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Sequential mutations in the interleukin-3 (IL3)/granulocyte-macrophage colony-stimulating factor/IL5 receptor beta-subunit genes are necessary for the complete conversion to growth autonomy mediated by a truncated beta C subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Binding of src-like kinases to the beta-subunit of the interleukin-3 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

SH2 domains recognize specific phosphopeptide sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Identification of a ten-amino acid proline-rich SH3 binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Phage display selection of ligand residues important for Src homology 3 domain binding specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Differential regulation of T cell antigen responsiveness by isoforms of the src-related tyrosine protein kinase p59fyn

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

The C-terminal SH2 domain of p85 accounts for the high affinity and specificity of the binding of phosphatidylinositol 3-kinase to phosphorylated platelet-derived growth factor beta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Function of Stat2 protein in transcriptional activation by alpha interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Prolactin activates the interferon-regulated p91 transcription factor and the Jak2 kinase by tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Receptor to nucleus signaling by prolactin and interleukin 2 via activation of latent DNA-binding factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Interactions among Janus kinases and the prolactin (PRL) receptor in the regulation of a PRL response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

In vivo association of v-Abl with Shc mediated by a non-phosphotyrosine-dependent SH2 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Molecular cloning of a phosphotyrosine-independent ligand of the p56lck SH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Phosphotyrosine-independent binding of a 62-kDa protein to the src homology 2 (SH2) domain of p56lck and its regulation by phosphorylation of Ser-59 in the lck unique N-terminal region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Phosphoinositide 3-kinases: a conserved family of signal transducers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Regulation of the p85/p110 phosphatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Yeast two-hybrid in vivo association of the Src kinase Lyn with the proto-oncogene product Cbl but not with the p85 subunit of PI 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Fyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Coordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Akt is a direct target of the phosphatidylinositol 3-kinase. Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Tyrosine phosphorylation and translocation of the c-cbl protein after activation of tyrosine kinase signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Direct T cell activation by chimeric single chain Fv-Syk promotes Syk-Cbl association and Cbl phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Tyrosine phosphorylation of DNA binding proteins by multiple cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097

Identification of Src, Fyn, Lyn, PI3K and Abl SH3 domain ligands using phage display libraries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.4.2097