(Q22010253)

English

The human apM-1, an adipocyte-specific gene linked to the family of TNF's and to genes expressed in activated T cells, is mapped to chromosome 1q21.3-q23, a susceptibility locus identified for familial combined hyperlipidaemia (FCH)

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The human apM-1, an adipocyte-specific gene linked to the family of TNF's and to genes expressed in activated T cells, is mapped to chromosome 1q21.3-q23, a susceptibility locus identified for familial combined hyperlipidaemia (FCH) (English)

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GOA release 2020-03-11

susceptibility locus

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object named as

G Schmitz

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G

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Schmitz

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PubMed publication ID

7 February 2023

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A Schäffler

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Schäffler

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PubMed publication ID

7 February 2023

E Orsó

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Orsó

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PubMed publication ID

7 February 2023

K D Palitzsch

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K D

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Palitzsch

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7 February 2023

C Büchler

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Büchler

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7 February 2023

W Drobnik

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Drobnik

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7 February 2023

A Fürst

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Fürst

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7 February 2023

J Schölmerich

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Schölmerich

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PubMed publication ID

7 February 2023

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publication date

5 July 1999

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Biochemical and Biophysical Research Communications

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260

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2

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416-25

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Genomic structure and PCR-SSCP analysis of the human CD40 ligand gene: its application to prenatal screening for X-linked hyper-IgM syndrome

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A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation

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The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death

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Mannose binding protein (MBP) enhances mononuclear phagocyte function via a receptor that contains the 126,000 Mr component of the Clq receptor

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Identification and characterization of the human adipocyte apM-1 promoter

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https://api.crossref.org/works/10.1006%2FBBRC.1999.0865

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Analysis of an expression profile of genes in the human adipose tissue

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Characterization of a novel TNF-like ligand and recently described TNF ligand and TNF receptor superfamily genes and their constitutive and inducible expression in hematopoietic and non-hematopoietic cells

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A role for leptin and its cognate receptor in hematopoiesis

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The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor

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Adipsin/acylation stimulating protein system in human adipocytes: regulation of triacylglycerol synthesis

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Structure of tumour necrosis factor

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Positional cloning of the mouse obese gene and its human homologue

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Anchored reference loci for comparative genome mapping in mammals.

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Linkage of familial combined hyperlipidaemia to chromosome 1q21-q23

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Mapping a gene for combined hyperlipidaemia in a mutant mouse strain.

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A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2.

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Novel B219/OB receptor isoforms: possible role of leptin in hematopoiesis and reproduction

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Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators

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Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells.

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A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes

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https://api.crossref.org/works/10.1006%2FBBRC.1999.0865

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AdipoQ is a novel adipose-specific gene dysregulated in obesity

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A susceptibility locus for early-onset non-insulin dependent (type 2) diabetes mellitus maps to chromosome 20q, proximal to the phosphoenolpyruvate carboxykinase gene

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The genes for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) are tandemly arranged on chromosome 17 of the mouse.

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https://api.crossref.org/works/10.1006%2FBBRC.1999.0865

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Is familial combined hyperlipidaemia a genetic disorder of adipose tissue?

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Scavenging, signalling and adhesion coupling in macrophages: implications for atherogenesis.

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https://api.crossref.org/works/10.1006%2FBBRC.1999.0865

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Defects of lipoprotein metabolism in familial combined hyperlipidaemia

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https://api.crossref.org/works/10.1006%2FBBRC.1999.0865

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Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

1 reference

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Peripheral blood mononuclear phagocyte subpopulations as cellular markers in hypercholesterolemia

1 reference

https://api.crossref.org/works/10.1006%2FBBRC.1999.0865

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Tumor necrosis factor alpha: a key component of the obesity-diabetes link

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10.1006/BBRC.1999.0865

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