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Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor
scientific article
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10490030
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10490030%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
title
Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10490030
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10490030%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
main subject
crystal structure
0 references
ligand binding
1 reference
based on heuristic
inferred from title
author
Christian Wiesmann
series ordinal
1
object named as
C Wiesmann
author given names
C
author last names
Wiesmann
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10490030
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10490030%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
author name string
Ultsch MH
series ordinal
2
author given names
M H
author last names
Ultsch
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10490030
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10490030%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
Bass SH
series ordinal
3
author given names
S H
author last names
Bass
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10490030
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10490030%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
de Vos AM
series ordinal
4
author given names
A M
author last names
de Vos
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10490030
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10490030%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
language of work or name
English
0 references
publication date
1 September 1999
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10490030
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10490030%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
number of pages
5
1 reference
based on heuristic
inferred from page(s)
published in
Nature
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10490030
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10490030%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
volume
401
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10490030
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10490030%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
issue
6749
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10490030
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10490030%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
page(s)
184-188
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10490030
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10490030%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
cites work
Functions of the neurotrophins during nervous system development: what the knockouts are teaching us.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotrophin receptors: mediators of life and death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth Factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An immunoglobulin-like domain determines the specificity of neurotrophin receptors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotrophin receptors: a window into neuronal differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotrophin-6 is a new member of the nerve growth factor family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NGF Binding to the trk Tyrosine Kinase Receptor Requires the Extracellular Immunoglobulin-like Domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structures of the neurotrophin-binding domain of TrkA, TrkB and TrkC
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The binding epitopes of neurotrophin-3 to its receptors trkC and gp75 and the design of a multifunctional human neurotrophin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High resolution mapping of the binding site of TrkA for nerve growth factor and TrkC for neurotrophin-3 on the second immunoglobulin-like domain of the Trk receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotrophin-3 acquires NGF-like activity after exchange to five NGF amino acid residues: molecular analysis of the sites in NGF mediating the specific interaction with the NGF high affinity receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An extended surface of binding to Trk tyrosine kinase receptors in NGF and BDNF allows the engineering of a multifunctional pan-neurotrophin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specificity determinants in neurotrophin-3 and design of nerve growth factor-based trkC agonists by changing central beta-strand bundle residues to their neurotrophin-3 analogs.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nerve growth factor binding site on TrkA mapped to a single 24-amino acid leucine-rich motif.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 bind to a single leucine-rich motif of TrkB.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The neurotrophin receptor p75 binds neurotrophin-3 on sympathetic neurons with high affinity and specificity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of the low affinity receptor-binding site in NGF allows neuronal survival and differentiation by binding to the trk gene product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A second determinant of binding to the p75 neurotrophin receptor revealed by alanine-scanning mutagenesis of a conserved loop in nerve growth factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cystine-knot growth-factor superfamily
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Processing of X-ray diffraction data collected in oscillation mode
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The CCP4 suite: programs for protein crystallography
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Improved methods for building protein models in electron density maps and the location of errors in these models
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystallographic R factor refinement by molecular dynamics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PROCHECK: a program to check the stereochemical quality of protein structures
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F43705
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/43705
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10490030
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10490030%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
Dimensions Publication ID
1009144394
0 references
PubMed publication ID
10490030
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10490030
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10490030%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
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